Ophthalmology And Visual Sciences

Matthew M. Harper, PhD

Portrait

Assistant Professor of Ophthalmology and Visual Sciences

Contact Information

Office: Bldg 42 VAMC
Iowa City, IA 52242
Office Phone: 319-338-0581

Email: matthew-harper@uiowa.edu

Education

BS, Biology, Iowa State University
PhD, Neuroscience Graduate Program, Iowa State University

Center, Program and Institute Affiliations

Stephen A. Wynn Institute for Vision Research

All Publications

Harper M, Kecova H, Kardon R, Sakaguchi D.  Functional characterization of the visual parameters of Monodelphis domestica using ERG, computerized PLR, and tonometry.  Vet Ophthalmol.  2013. 

Mohan K, Harper M, Kecova H, Ye E, Lazic T, Sakaguchi D, Kardon R, Grozdanic S.  Characterization of structure and function of the mouse retina using pattern electroretinography, pupil light reflex, and optical coherence tomography.  Vet Ophthalmol.  2012 September. 15 Suppl. 2.
[PubMed]

Mohan K, Kecova H, Hernandez-Merino  E, Kardon R, Harper M.  Retinal ganglion cell damage in an experimental rodent model of blast-mediated traumatic brain injury.  Invest Ophthalmol Vis Sci.  2012 May 15. 54(5):3340-50.
[PubMed]

Mohan K, Lazik T, Kardon R, Harper M, Grozdanic S.  Effect Of Age On Blast-Induced Retinal And Optic Nerve Dysfunction In A Mouse Model Of Traumatic Brain Injury.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 8-10, 2012.  2012 May 8. 

Wang Q, Grozdanic S, Harper M, Hamouche N, Kecova H, Lazic T, Yu C.  Exploring Raman spectroscopy for the evaluation of glaucomatous retinal changes.  J Biomed Opt.  2011 October. 16(10):107006.
[PubMed]

Harper M, Grozdanic S, Blits B, Kuehn M, Zamzow D, Buss J, Kardon R, Sakaguchi D.  Transplantation of BDNF-secreting mesenchymal stem cells provides neuroprotection in chronically hypertensive rat eyes.  Invest Ophthalmol Vis Sci.  2011 June 23. 52(7):4506-15.
[Link]

Mohan K, Lazik T, Harper M, Larson S, Noble J, Kardon R, Grozdanic S.  Retinal Axonal Injury And Oxidative Stress Are Acute Characteristics Of Experimental Traumatic Blast Injury.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 1-5, 2011.  2011 May 5. 

Harper M, Mohan K, Lazik T, Grozdanic S, Kardon R.  Retinal Ganglion Cell and Optic Nerve Functional and Structural loss in a Rodent Model of Blast-Induced Traumatic Brain Injury.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 1-5, 2011.  2011 May 5. 

Grozdanic S, Harper M, Gallup J, Jacobson S, Kecova H, Soltek S, Umansky V, Eichmueller S, Kardon R, Lazic T.  Immunological Characterization of Non-paraneoplastic Auto-immune Retinopathy (npAIR) and Cancer Associated Retinopathy (CAR).  ARVO Annual Meeting, Ft. Lauderdale, FL, May 1-5, 2011.  2011 May 4. 

Hernandez-Merino E, Kecova H, Jacobson S, Harper M, Lazik T, Kardon R, Grozdanic S.  Analysis Of Retinal Nerve Fiber Layer Thickness And Retinal Ganglion Cell Function During Acute Elevation Of Intraocular Pressure And Its Relationship With Ocular Perfusion Pressure In The Canine Eye.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 1-5, 2011.  2011 May 2. 

Kecova H, Hernandez-Merino E, Jacobson S, Crumpton A, Pryde M, Hamouche K, Kardon R, Harper M, Grozdanic S.  Effect of Cholinergic Drugs on Optic Nerve Structure and Function in Glaucoma.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 1-5, 2011.  2011 May 2. 

Jiang B, Harper M, Kecova H, Adamus G, Kardon R, Grozdanic S, Kuehn M.  Neuroinflammation in advanced canine glaucoma.  Mol Vis.  2010 October 15. 16:2092-108.
[Link]

Grozdanic S, Lazic T, Kuehn M, Harper M, Kardon R, Kwon Y, Lavik E, Sakaguchi D.  Exogenous modulation of intrinsic optic nerve neuroprotective activity.  Graefes Arch Clin Exp Ophthalmol.  2010 August. 248(8):1105-16.
[PubMed]

Mohan K, Harper M, Schipull K, Ghosh A, Kanthasamy A, Kanthasamy A, Kardon R, Grozdanic S.  Functional Retinal Ganglion Cell PERG Deficits in an Acute and Chronic Mouse Model of Parkinson’s Disease.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 2-6-2010.  2010 May 6. 

Nzokwe R, Kecova H, Kardon R, Park S, Hamouche K, Jacobson S, Alward E, Harper M, Grozdanic S.  Early Functional and Structural Optic Nerve Deficits in a Canine Model of Compressive Optic Neuropathy.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 2-6-2010.  2010 May 5. 

Grozdanic S, Kecova H, Harper M, Kuehn M, Lavik E, Kardon R.  BDNF Mediated Functional and Structural Optic Nerve Protection in Canine Hypertensive Eyes.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 2-6-2010.  2010 May 4. 

Kecova H, Kardon R, Lavik E, Park S, Jacobson S, Hamouche K, Alward E, Harper M, Grozdanic S.  Treatment of Laser-Induced Retinal Injury and Visual Loss Using Sustained Release of Intra-Vitreal Neurotrophic Growth Factors.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 2-6-2010.  2010 May 4. 

Harper M, Eggers L, Kuehn M, Sakaguchi D, Kardon R, Grozdanic S.  Quantification and Correlation of Neurotrophic Factor Expression With Medical Histories in Healthy and Glaucomatous Tissue.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 2-6-2010.  2010 May 3. 

Mohan K, Harper M, Ghosh A, Kanthasamy A, Kanthasamy A, Kardon R, Grozdanic S.  Protein kinase C delta mediates retinal ganglion cell function loss following MPTP treatment in mice.  Invest Ophthalmol Vis Sci.  2010. 

Grozdanic S, Kecova H, Harper M, Nilaweera W, Kuehn M, Kardon R.  Functional and structural changes in a canine model of hereditary primary angle-closure glaucoma.  Invest Ophthalmol Vis Sci.  2010 January. 51(1):255-63.
[PubMed]

Harper M, Adamson L, Blits B, Bunge M, Grozdanic S, Sakaguchi D.  Brain-derived neurotrophic factor released from engineered mesenchymal stem cells attenuates glutamate- and hydrogen peroxide-mediated death of staurosporine-differentiated RGC-5 cells.  Exp Eye Res.  2009 October. 89(4):538-48.
[PubMed]

Kecova H, Harper M, Kardon R, Adamus G, Grozdanic S.  Systemic and Intraocular IVIg Therapy for Auto-immune Retinopathies.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 3-7,2009.  2009 May 7. 

Grozdanic S, Kecova H, Harper M, Nilaweera W, Kuehn M, Kardon R.  Cholinergic Drug Induced Reversal of Early Functional Deficits in Glaucoma.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 3-7,2009.  2009 May 5. 

Harper M, Sakaguchi D, Kuehn M, Kwon Y, Kardon R, Bemelmans A, Kostic C, Arsenijevic Y, Grozdanic S.  Comparison of Visual Preservation After Transplantation of BDNF or GDNF Secreting Mesenchymal Stem Cells in Glaucomatous Rat Eyes.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 3-7,2009.  2009 May 5. 

Harper M, Ye E, Blong E, Jacobson M, Sakaguchi D.  Integrins contribute to initial morphological development and process outgrowth in rat adult hippocampal progenitor cells.  J Mol Neurosci.  2009 March. 40(3):269-83.
[PubMed]

Harper M, Eggers L, Holland E, Boll A, Sterner N, Kuehn M, Sakaguchi D, Kardon R, Grozdanic S.  Quantification of Neurotrophic Factor Expression in Human and Canine Glaucomatous and Normal Retinas.  ARVO Annual Meeting, Ft. Lauderdale, FL, April 27-May 1, 2008.  2008 May 1. 

Harper M, Eggers L, Holland E, Boll A, Sterner N, Kuehn M, Sakaguchi D, Kardon R, Grozdanic S.  Quantification of Neurotrophic Factor Expression in Human and Canine Glaucomatous and Normal Retinas.  ARVO Annual Meeting, Ft. Lauderdale, FL, May 1-7, 2008.  2008 May 1. 

Sakaguchi D, Harper M, Adamson L, Blits B, Bunge M, Grozdanic S.  Brain-derived neutrotrophic Factor (BDNF) released from engineered mesenchymal stem cells (MSCs) attenuates glutamate- and hydrogen peroxide-mediated death of staurosporine differentiated RGC-5 cells.  ARVO Annual Meeting, Ft. Lauderdale, FL, April 27-May 1, 2008.  2008 April 28. 

Grozdanic S, Harper M, Kecova H, Nilaweera W, Boll A, Kuehn M, Sakaguchi D, Kardon R.  Antibody Mediated Retinopathy – New Mechanisms and Treatment Strategies.  ARVO Annual Meeting, Ft. Lauderdale, FL, April 27-May 1, 2008.  2008 April 27. 

Grozdanic S, Harper M, Kecova H.  Antibody-mediated retinopathies in canine patients: mechanism, diagnosis, and treatment modalities.  Vet Clin North Am Small Anim Pract.  2008 March. 38(2):361-87.
[PubMed]

Sakaguchi D, Hoffelen S, Greenlee M, Harper M, Au D.  Cell birth and death in the developing retina of the Brazilian opossum, Monodelphis domestica.  Brain Res.  2008 February 21. 1195:28-42.
[PubMed]

Sakaguchi D, Harper M, Grozdanic S, Blits B, Kuehn M, Kwon Y, Reger R, Prockop D, Bunge M, Kardon R.  Preservation of Visual Function after Intraocular Transplantation of BDNF Secreting Mesenchymal Stem Cells in Glaucomatous Rat Eyes.  ARVO Annual Meeting, Ft. Lauderdale, Fl, May 6-10, 2007.  2007 May 8. 

Sakaguchi D, Van Hoffelen S, Theusch E, Parker E, Orasky J, Harper M, Benediktsson A, Young M.  Transplantation of neural progenitor cells into the developing retina of the Brazilian opossum: an in vivo system for studying stem/progenitor cell plasticity.  Dev Neurosci.  2004. 26(5-6):336-45.
[PubMed]

Date Last Modified: 06/07/2014 - 21:56:23