Ophthalmology And Visual Sciences

Young H. Kwon, MD, PhD

Portrait

Clifford M. and Ruth M. Altermatt Professor of Glaucoma
Professor of Ophthalmology and Visual Sciences

Contact Information

Primary Office: 11190B  PFP
Iowa City, IA 52242
Primary Office Phone: 319-356-3938

Email: young-kwon@uiowa.edu

Education

BS, Biology, Massachusetts Institute of Technology
MD, Yale University School of Medicine
PhD, Neuroscience, Massachusetts Institute of Technology

Internship, Internal Medicine, Mt Auburn Hospital, Harvard Medical School
Residency, Ophthalmology, Massachusetts Eye & Ear Infirmary
Fellowship, Glaucoma, Yale University School of Medicine

Licensure and Certifications

State of Iowa Medical License, Iowa Board of Medicine
Connecticut Medical License- Permanent (inactive)
Temporary Massachusetts Medical License (inactive)
ABO Certification, American Board of Ophthalmology
NBME Diplomate, National Board of Medical Examinars

Research Summary

Glaucoma is the second leading cause of blindness in the United States, but can be managed if diagnosed early and treated appropriately. Adequate diagnosis and treatment depends on measurement of changes in the optic nerve cupping. We have developed a novel computer software method to automatically measure the optic nerve changes from digital stereo optic nerve photographs. This image processing alogorithm is based on pixel feature classification algorithm, which has previously been developed for the purpose of evaluating diabetic retinopathy in digital fundus photographs. We have utilized novel, biologically plausible pixel feature classification algorithm to automatically segment the optic disc into cup and rim, and compared its performance to the reference standard, i.e., computer-assisted planimetry by human glaucoma experts. The early results are promising. We hope to eventually develop and refine the algorithm to objectively diagnose and detect progression of glaucomatous optic nerve cupping from serial digital stereo fundus photographs. Dr. Kwon is also interested in the education of public regarding glaucoma through free on- line publications. See www.medrounds.org/glaucoma-guide.

Center, Program and Institute Affiliations

Institute for Vision Research
Iowa Institute for Biomedical Imaging

Selected Publications

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Miri M, Lee K, Niemeijer M, Abramoff M, Kwon Y, Garvin M.  Multimodal segmentation of the optic disc and cup from stereo fundus and SD-OCT images .  Proceedings of SPIE Medical Imaging, Imaging Processing.  2013 February. 8669:8669-23.

Miri M, Abramoff M, Lee K, Niemeijer M, Wahle A, Kwon Y, Garvin M.  A multimodal Machine-Learning-Based Approach for Segmenting the Optic Disc and Cup in Fundus and SD-OCT Images.  Invest. Ophthalmol. Vis. Sci. Abstr..  2013. 

Lee K, Kwon Y, Abramoff M, Garvin M, Sonka M.  Correction of the retinal angle in SD-OCT of glaucomaatous eyes provides better reproducibility of optic nerve head parameters.  Invest. Ophthalmol. Vis. Sci. Abstr..  2013. 

Seo S, Sullivan-Timpe F, Roos B, Robin A, Stone E, Kwon Y, Alward W, Fingert J.  Identification of proteins that interact with Tank Binding Kinase 1 (TBK1) and testing for mutations associated with glaucoma.  Current Eye Res.  2013. 38(2):310-315.
[Link]

Risma J, Alward W, Fingert J, Kwon Y.  Diaton Transpalpebral tonometry in patients with glaucoma and glaucoma drainage devices - A preliminary study for its use in keratoprosthesis patients.  Resident/Fellow Research Day, Department of Ophthalmology and Visual Sciences, University of Iowa.  2012 April. 

Tienor B, Abramoff M, Johnson C, Kwon Y.  Optic disc size in glaucoma patients with high myopia.  Resident/Fellow Research Day, Department of Ophthalmology and Visual Sciences, University of Iowa.  2012 April. 

Gauger E, Kwon Y, Mahajan V.  The effect of pars plana vitrectomy in patients with glaucoma.  Resident/Fellow Research Day, Department of Ophthalmology and Visual Sciences, University of Iowa.  2012 April. 

Wandling G, Rauen M, Goins K, Kitzmann A, Sutphin J, Kwon Y, Alward W, Wagoner M.  Glaucoma therapy escalation in eyes with pseudophakic corneal edema after penetrating keratoplasty and Descemet's stripping automated endothelial keratoplasty..  International ophthalmology.  2012 February. 32(1):14-Sep.
[PubMed]

Garvin M, Abramoff M, Lee K, Niemeijer M, Sonka M, Kwon Y.  2-D pattern of nerve fiber bundles in glaucoma emerging from spectral-domain optical coherence tomography.  Invest Ophthalmol Vis Sci.  2012. 53(1):483-9.
[PubMed]

Fingert J, Roos B, Sullivan-Timpe F, Miller K, Oetting T, Wang K, Kwon Y, Scheetz T, Stone E, Alward W.  Analysis of ASB10 variants in open angle glaucoma. .  Human Molecular Genetics.  2012. 21(20):4543-4548.
[PubMed]

Date Last Modified: 08/22/2013 - 14:08:40