Obstetrics and Gynecology

Stephen K. Hunter, MD, PhD


Professor of Obstetrics and Gynecology  - Maternal/Fetal Medicine
Professor of Biomedical Engineering

Contact Information

Primary Office: 31312 Pomerantz Family Pavilion
Iowa City, IA 52242

Phone: 319-356-1929

Email: stephen-hunter@uiowa.edu
Web: Physician Profile


BS, University of Utah
PhD, University of Utah
MD, University of Utah

Residency, Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Fellowship, Maternal-Fetal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa

Licensure and Certifications

DEA Controlled Substance
Iowa Controlled Substance
Maternal-Fetal Medicine Subspecialty, American Board of Obstetrics and Gynecology
Obstetrics and Gynecology, American Board of Obstetrics and Gynecology

Education/Training Program Affiliations

Biosciences Graduate Program
Interdisciplinary Graduate Program in Translational Biomedicine

Research Summary

Diabetes in pregnancy; Bioartificial Pancreas (BAP); Fetal Therapy; Neovascularization around hollow Fiber Based Bioartificial Organs Using Biologically Active Substances

All Publications

Adams A, Hubb A, Santillan M, Nishimura T, Rubac R, Gravatt L, Higdon E, Schroeder K, Conklin J, Bender R, Hunter S, Santillan D.  Adherence to the updated guidelines for the prevention of perinatal Group B streptococcal disease.  Proc Obstet Gynecol.  2015 February. 4(3):2 p.

Santillan M, Pelham C, Ketsawatsomkron P, Santillan D, Davis D, Devor E, Gibson-Corley K, Scroggins S, Grobe J, Yang B, Hunter S, Sigmund C.  Pregnant mice lacking indoleamine 2,3-dioxygenase exhibit preeclampsia phenotypes.  Physiol Rep.  2015 January 19. 3(1):pii: e12257.

Santillan M, Santillan D, Scroggins S, Minn J, Leslie K, Hunter S, Zamba G, Gibson-Corley K, Grobe J.  Vasopressin secretion in human pregnancy predicts the development of preeclampsia as early as the sixth week of gestation .  Pregnancy Hypertens.  2015 January. 5(1):25-6.

Mhyre J, D'Oria R, Hameed A, Lappen J, Holley S, Hunter S, Jones R, King J, D'Alton  M.  The maternal early warning criteria: a proposal from the national partnership for maternal safety.  J Obstet Gynecol Neonatal Nurs.  2014 November. 43(6):771-9.

Mhyre J, D'Oria R, Hammed A, Lappen J, Holley S, Hunter S, Jones R, King J, D'Alton  M.  The maternal early warning criteria: a proposal from the national partnership for maternal safety.  Obstet. Gynecol..  2014 October. 124(4):782-6.

Santillan M, Leslie K, Hamilton  W, Boese B, Ahuja M, Hunter S, Santillan  D.  Collection of a lifetime: a practical approach to developing a longitudinal collection of women's healthcare biological samples..  Eur J Obstet Gynecol Reprod Biol.  2014 August. 179:94-9.

Santillan  M, Santillan D, Scroggins S, Min J, Sandgren J, Pearson  N, Leslie  K, Hunter S, Zamba  G, Gibson-Corley K, Grobe  J,  .  Vasopressin in Preeclampsia: A Novel Very Early Human Pregnancy Biomarker and Clinically Relevant Mouse Model.  Hypertension.  2014 July 7. 

Santillan  M, Kowalski J, Santillan D, Fleener  D, Netz R, Hunter S, Haynes W.  Determinants of Changes in Flow Mediated Dilation and Pulse Wave Analysis Throughout All Trimesters of Normal Pregnancies.  2014. 

Santillan M, Ramachandram S, Santillan D, Hunter S, Leslie K, Devor E.  Setting the Tone: Human Placenta microRNA expression is Established in Gestation.  Submitted to Am J Obstet Gynecol.  2014. 

Kowalski J, Santillan D, Netz R, Sinkey C, Fleener D, Hunter S, Santillan M.  Flow mediated vasodilation predicts the development of gestational diabetes mellitus.  Proc Obstet Gynecol.  2013 December. 3(3):2 p.

Taylor J, Conklin J, Hunter S, Empey R, Tyler E, Christensen A, Talcott K, Ballas Z, Santillan D, Santillan M.  Defining normal IgG changes throughout pregnancy.  Proc Obstet Gynecol.  2013 July. 3(2):8.

Santillan D, Hamilton W, Christenson A, Talcott K, Gravatt L, Santillan M, Hunter S.  The Effects of Preeclampsia on Signaling to Hematopoietic Progenitor Cells.  Proc Obstet Gynecol.  2013 March. 3(1):3.

Kyser K, Lu X, Santillan D, Santillan M, Hunter S, Cahill A, Cram P.  The Association Between Hospital Obstetrical Volume and Maternal Postpartum Complications (Editor's Choice).  Am J Obstet Gynecol.  2012 July. 207:42.e1-17 .

Empey R, Santillan D, Santillan M, Tyler E, Hunter S, Smith E, Stegmann B.  The influence of fetal sex on patterns of change in anti-Mullerian hormone during pregnancy.  Proc Obstet Gynecol.  2012 May. 2(3):Article 4 [2 pages].

Santillan M, Santillan D, Fleener D, Stegmann B, Zamba G, Hunter S, Yankowitz J.  Single umbilical artery: does side matter?.  Fetal Diagn Ther.  2012. 32(3):201-208.

Santillan D, Rai K, Santillan M, Krishnamachari Y, Salem A, Hunter S.  Efficacy of Polymeric Encapsulated C5a peptidase-based Group B Streptococcus Vaccines in a Murine Model..  Am J Obstet Gynecol.  2011 September. 205(3):249.e1-8.

Zhao A, Hunter S, Rodgers V.  Theoretical Prediction of Induction Period from Transient Pore Evolvement in Polyester-Based Microparticles.  J Pharma Sci.  2010 November. 99(11):4477-4487.

Santillan M, Santillan D, Sigmund C, Hunter S.  From molecules to medicine: a future cure for preeclampsia?.  Drug News Perspect.  2009 November. 22(9):531-41.

Santillan M, Santillan D, Sigmund C, Hunter S.  From molecules to medicine: A future cure for preeclampsia?.  Drug News Perspect.  2009 November. 22(9):531-541.

Santillan D, Santillan M, Hunter S.  Cell encapsulation as a potential nondietary therapy for maternal phenylketonuria.  Am J Obstet Gynecol.  2009 September. 201(3):289.e1-289.e6.

Santillan M, Hunter S.  Preeclampsia/Eclampsia: An Immediate and Long Term Problem.  The Iowa Perinatal Letter.  2008. 29(4).

Hunter S.  The Rising Pre-term Delivery Rate in Iowa - Three things We Can Do Now.  The Iowa Perinatal Letter.  2008. 29(1).

Santillan D, Andracki M, Hunter S.  Protective Immunization in Mice Against group B Streptococci Using Encapsulated C5a Peptidase.  Am J Obstet Gynecol.  2008 January. 198(1):114e1-114e6.

Tilakaratne H, Yang B, Hunter S, Andracki M, Rodgers V.  Can myoglobin expression in pancreatic beta cells improve insulin secretion under hypoxia? An exploratory study with transgenic porcine islets.  Artif Organs.  2007 July. 31(7):521-531.

Hunter S.  Obstetrical High Risk Legal Situations.  The Iowa Perinatal Letter.  2007. 28(4).

Tilakaratne H, Hunter S, Andracki M, Benda J, Rodgers V.  Characterizing short-term release and neovascularization potential of multi-protein growth supplement delivered via alginate hollow fiber devices..  Biomaterials.  2007 January. 28(1):89-98.

Facer S, Zaharias R, Andracki M, Lafoon J, Hunter S, Schneider G.  Rotary Culture Enhances Pre-osteoblast Aggregation and Mineralization..  J Dent Res.  2005 June. 84(6):542-547.

Goldner W, Kraus V, Sivitz W, Hunter S, Dillon J.  Cyclic Changes in Glycemia Assessed By Continuous Glucose Monitoring System During Multiple Complete Menstrual Cycles in Women with Type I Diabetes.  Diabetes Technol Ther.  2004 August. 6(4):473-480.

Tran N, Hunter S, Yankowitz J.  Oral hypoglycemic agents in pregnancy.  Obstet Gynecol Surv.  2004 June. 59(6):456-63.

Tran N, Hunter S, Yankowitz J.  Oral Hypoglycemic Agents in Pregnancy.  Obstetrical & Gynecological Survey.  2004 June. 59(6):456-463.

Tilakaratne H, Hunter S, Rodgers V.  Mathematical Modeling of Myoglobin Facilitated Transport of Oxygen in Devices Containing Myoglobin-Expressing Cells.  Math Biosci.  2002 April. 176(2):253-267.

Hansen W, Fretz P, Hunter S, Yankowitz J.  Leukemia in pregnancy and fetal response to multiagent chemotherapy.  Obstet Gynecol.  2001 May. 97(5 (Part 2)):809-812.

Hunter S, Krieg A, Andracki M.  Biodegradable Microspheres Containing Group B Streptococcus (GBS) Vaccine: Immune Response in Mice.  Am J Obstet Gynecol.  2001. 185(5):1174-1179.

Hunter S.  Gestational Diabetes: Questions and Answers.  The Iowa Perinatal Letter.  2001. 12(4):14-16.

Guthmiller J, Hassebroek-Johnson J, Weenig D, Johnson G, Kirchner H, Kohout F, Hunter S.  Periodontal disease in pregnancy complicated by type 1 diabetes mellitus.  J Periodontal.  2001. 72(11):1485-1490.

Andrews J, Diekema D, Hunter S, Rhomberg P, Pfaller M, Jones R, Doern G.  Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere.  Am J Obstet Gynecol.  2000 October. 183(4):859-62.

Hunter S.  Present and future perspectives on the use of free or encapsulated pancreatic islet cell transplantation as a treatment of pregnancy complicated by type I diabetes.  J Matern Fetal Med.  2000 January. 9(1):46-51.

Kao J, Rose R, M Y, Hunter S, Rodgers V.  In-vivo Biocompatibility Evaluation of Cibacron Blue-Agarose.  J Biomed Mater Res.  1999 December. 47(4):537-542.

Peleg D, Hunter S.  Perinatal management of women with immune thrombocytopenic purpura: survey of United States perinatologists..  Am J Obstet Gynecol.  1999 March. 180(3 Pt 1):645-9.

Hunter S, Kao J, Wang Y, Benda J, Rodgers V.  Promotion of neovascularization around hollow fiber bioartificial organs using biologically active substances.  ASAIO J.  1999. 45(1):37-40.

Hunter S, Wang Y, Rodgers V.  Bioartificial pancreas (BAP) use in diabetic pregnancy.  Am Soc Artif Int Organs.  1999 January. 45(1):13-17.

Peleg D, Kennedy C, Hunter S.  Intrauterine growth restriction: identification and management.  Am Fam Physician.  1998 August. 58(2):453-60, 466-7.

Peleg D, Kennedy C, Hunter S.  Intrauterine growth restriction: Identification and management..  Am Family Physician.  1998 August. 58(2):453-460, 446-447.

Hunter S, Wang Y, Weiner C, Niebyl J.  Encapsulated beta-islet cells as a bioartificial pancreas to treat insulin-dependent diabetes during pregnancy.  Am J Obstet Gynecol.  1997 October. 177(4):746-52.

Hunter S.  Asthma in Pregnancy.  The Iowa Perinatal Letter.  1997. 18(1).

Hunter S, Yankowitz J.  Medical Fetal Therapy.  Mosby Yearbook Inc.  1996. 

Hunter S, Weiner C.  Obstetric Hemorrhage.  Churchill Livingstone.  1996. 

Hunter S.  Random blood glucose, glucose tolerance, "postprandial glucose" and urine glucose tests.  WB Saunders.  1996. 

Hunter S, Martin M, Benda J, Zlatnik F.  Liver transplant after massive spontaneous hepatic rupture in pregnancy complicated by preeclampsia.  Obstet Gynecol.  1995 May. 85(5 Pt 2):819-22.

Merrill D, Hunter S.  Use of oxytocin for induction and augmentation of labor.  Postgraduate Obstetrics & Gynecology.  1995. 15(18):1-7.

Hunter S, Neeld J, Scott J, Olsen D, Urry R, Cichocki T.  Developing an artificial fallopian tube: successful in vitro trials in mice.  Fertil Steril.  1990 June. 53(6):1083-6.

Hunter S, Scott J, Hull D, Urry R.  The gamete and embryo compatibility of various synthetic polymers.  Fertil Steril.  1989. 50:110-116.

Gregonis D, Buerger D, Van Wagenen R, Hunter S, Andrade J.  Poly (ethylene glycol) surfaces to minimize protein absorption.  Abst 2nd World Cong Biomat.  1984. 

Hunter S, Gregonis D, Coleman D, Hanover B, Stephan R, Jacobsen S.  Surface modification of polyurethane to promote long-term patency of peritoneal access devices.  Trans Am Soc Artif Intern Organs.  1983. 29:250-254.

Hunter S, Gregonis D, Coleman D, Andrade J, Kessler T.  Molecular weight characterization of pre-and post-implant artificial heart polyurethane materials.  Trans Am Soc Artif Intern Organs.  1982. 28:473-7.

Date Last Modified: 08/04/2015 - 09:28:35