William Talman, MD


Specialty: Autonomic Disorders
Director, VA Medical Center Program, Neurology
Professor of Neurology

Contact Information

Primary Office: S209 GH
Iowa City, IA 52242
Phone: 319-356-8750

Web: Neurobiology and Circulatory Control Laboratory


BA, Virginia Military Institute
MD, University of Virginia School of Medicine

Fellowship, Neurology, Cornell University
Internship, Internal Medicine, Case Western Reserve University
Residency, Internal Medicine, Case Western Reserve University
Residency, Neurology, Cornell University

Licensure and Certifications

State of New Jersey
State of New York
State of Iowa
State of Virginia License

Education/Training Program Affiliations

Biosciences Graduate Program
Interdisciplinary Graduate Program in Neuroscience

Research Summary

Cardiovascular regulation by the CNS. pharmacology, neuroanatomy, immunohistochemistry, physiology, baroreflex, dominant negative, neurotransmitter, cerebral blood flow, neurogenic hypertension, glutamate, nitric oxide, cardiovascular Our laboratory research focuses on central cardiovascular and circulatory control. We study the role played by excitatory amino acids and nitric oxide as possible neurotransmitters in central cardiovascular reflex signal transduction. Current studies investigate the link between activation of excitatory amino acid receptors and release of nitric oxide in specific nuclei of the brain stem. In separate studies we investigate the role played by arterial baroreceptor reflexes in cerebrovascular control. Those studies focus on the role played by nitroxidergic parasympathetic nerves in cerebrovascular control and on the preganglionic central pathways that regulate those nerves.

Selected Publications

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Talman W, Lin L.  Sudden death following selective neuronal lesions in the rat nucleus tractus solitarii..  Autonomic neuroscience : basic & clinical.  2012 December. 

Talman W.  Back to Basics.  Huffington Post Science.  2012 October 30. 

Talman W, Dragon D, Jones S, Moore S, Lin L.  Sudden death and myocardial lesions after damage to catecholamine neurons of the nucleus tractus solitarii in rat..  Cellular and molecular neurobiology.  2012 October. 32(7):1119-26.

Talman W.  What Will I Be When I Grow Up?.  Huffington Post Science;  2012.  Available from:

Talman W.  The Benefits of Studying Chimpanzees.  Huffington Post Science;  2012.  Available from:

Lin L, Nitschke Dragon D, Jin J, Tian X, Chu Y, Sigmund C, Talman W.  Decreased expression of neuronal nitric oxide synthase in the nucleus tractus solitarii inhibits sympathetically mediated baroreflex responses in rat..  The Journal of physiology.  2012 August. 590(Pt 15):3545-59.

Talman W.  Views of Translational Research from a Somewhat Translational Scientist.  J. Investigative Medicine.  2012 August. 60:863-8.

Talman W, Lin L, Nitschke Dragon D, Jin J, Tian X, Chu Y, Sigmund C.  Decreased Expression of Neuronal Nitric oxide Synthase in the Nucleus Tractus Solitarii Inhibits Sympathetically Mediated Baroreflex Responses in Rat.  J Physiol..  2012 August 1. 590(15):3545-59.

Talman W, Hobin J, Deschamps A, Bockman R, Cohen S, Dechow P, Eng C, Galey W, Morris M, Prabhakar S, Raj U, Rubenstein P, Smith J, Stover P, Sung N, Galbraith R.  Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles.  J Transl Med. .  2012 April 13. 10(1):72.

Spencer S, Talman W.  Centrally administered bombesin modulates gastric motility..  Peptides.  8(5):887-91.

Date Last Modified: 08/04/2015 - 09:28:35