Neurology

Andrew Russo, PhD

Portrait

Professor of Molecular Physiology and Biophysics
Professor of Neurology

Contact Information

Email: andrew-russo@uiowa.edu
Web: Departmental Profile

Education

BA, Biology (concentrations in biochemistry and microbiology), University of California
PhD, Biochemistry, University of California

Post Doctoral, Molecular Neurobiology, Dept. Medicine, UCSD

Education/Training Program Affiliations

Biosciences Graduate Program
Department of Molecular Physiology and Biophysics PhD
Interdisciplinary Graduate Program in Genetics
Interdisciplinary Graduate Program in Molecular and Cellular Biology
Interdisciplinary Graduate Program in Neuroscience
Interdisciplinary Graduate Program in Translational Biomedicine
Medical Scientist Training Program

Research Summary

My research interest is to understand how neurons respond to changes in their environment. We have focused on regulation of CGRP and its actions in the context of trigeminal-mediated disorders, especially migraine. A recent focus of the lab is a CGRP-sensitized transgenic mouse model we generated based on clinical reports that injection of CGRP is able to induce a migraine, but not in people who do not suffer from migraine. These sensitized mice overexpress the RAMP1 subunit of the CGRP receptor in the nervous system. The RAMP1 mice have elevated CGRP-induced neurogenic inflammation, mechanical allodynia, and light aversion analogous to photophobia. In collaborative projects, the lab is also studying the beneficial effects of CGRP and RAMP1 against hypertension and obesity, with overall goals to develop effective diagnostic and therapeutic strategies for neurovascular disorders.

All Publications

Russo A, Kaiser  E, Kuburas  A, Recober  A.  Modulation of CGRP-induced light aversion in wildtype mice by a 5HT1B/D agonist.  J Neurosci .  2012. 

Russo A, Ferrari M, VanDenBrink  A.  Scholarship Review.  2011 June. 51(6):1047-1048.

Russo A, Raddant A.  CGRP in migraine: Intersection of peripheral inflammation and central modulation.  2011. 13(36).
[PubMed]

Russo A, Xie  W, Fisher  J, Lynch  T, Luo  M, Evans  T, Neff  T, Zhou  W, Zhang  Y, Ou  Y, Bunnett  N, Goodheart  M, Parekh  K, Liu  X, Engelhardt  J.  CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice.  J Clin Invest.  2011. 121:3144-3158.
[PubMed]

Russo A, Park  K, Fletcher  J, Raddant  A.  Epigenetic regulation of the calcitonin gene-related peptide gene in trigeminal glial.  2011. 31:614-624.
[PubMed]

Russo A, Zhang  Z, Liu  X, Morgan  D, Kuburas  A, Thedens  D, Rahmouni  K.  Neuronal receptor activity-modifying protein 1 promotes energy expenditure in mice.  2011. 60:1063-1071.
[PubMed]

Russo A, Sabharwal R, Abboud F, Chapleau M.  Transgenic expression of CGRP receptor subunit RAMP1 in nervous system improves autonomic regulation and prevents angiotensin II hypertension.  FASEB J.  2011. 

Russo A, Raddant A, Kuburas A, Recober A.  A physiological trigger of light aversion in a mouse model of migraine.  2010. 696.

Russo A, Peotta V, Weiss R, Zimmerman K, Lu Y, Abboud F, Chapleau M.  Consequences of enhanced CGRP receptor signaling on cardiac function and mortality post-myocardial infarction.  FASEB J.  2010. 24(1037).

Russo A, Raddant A, Park K, Fletcher J.  Epigenetic regulation of CALCA gene expression in trigeminal glia.  2010. 

Russo A, Fletcher J, Park K, Zhang Z.  Epigenetic regulation of the CALCA gene.  2010. 646.

Russo A, Kaiser E, Kuburas A, Recober A, Marquez dePrado  B.  Factors influencing light aversion in a migraine mouse model.  2010. 80.

Russo A, Park  K.  Genetic regulation of CGRP and its actions.  Springer.  2010. 

Russo A, Recober  A, Kaiser  E, Kuburas  A.  Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP.  Neuropharmacology.  2010. 58:156-165.
[PubMed]

Russo A, Thompson  S, Recober  A, Vogel  T, Kuburas  A, Owens  J, Sheffield  V, Stone  E.  Light-aversion in mice depends on nonimage-forming irradiance detection.  2010. 124:821-827.
[PubMed]

Russo A, Kaiser E.  Photophobia-like behavior in a preclinical model.  2010. 

Russo A, Wang J, Zhang Z, Saadi I, Fu X, Engel J, Kuburas A, Amendt B.  PIAS1 and PIASy Regulate PITX2 Activity During Tooth Development.  2010. 

Russo A, Chrissobolis  S, Zhang  Z, Kinzenbaw  D, Lynch  C, Faraci  F.  RAMP1 augments cerebrovascular responses to CGRP and inhibits angiotensin II-induced vascular dysfunction.  Stroke.  2010. 41:2329-2334.
[PubMed]

Russo A, Sabharwal  R, Zhang  Z, Lu  Y, Abboud  F, Chapleau  M.  Receptor activity-modifying protein-1 increases baroreflex sensitivity and attenuates angiotensin-induced hypertension.  2010. 55:627-635.
[PubMed]

Russo A, Schwedt T, Goadsby P.  Scholarship Review.  2010. 50:520-526 .
[PubMed]

Russo A, Regan  J, VanPutte  C.  Seeley’s Anatomy and Physiology.  9. 2010.

Russo A.  Scholarship Review.  2009 August. 
[Link]

Russo A, Kuburas  A, Kaiser  E, Raddant A, Recober A.  A Potential Preclinical Migraine Model: CGRP-Sensitized Mice.  2009. 1(5):264-270 .
[PubMed]

Russo A, Recober  A.  Calcitonin gene-related peptide: an update on the biology.  2009. 22:241-246 .
[PubMed]

Russo A, Recober , Kaiser E, Kuburas A, Wemmie J, Anderson M.  CGRP-induced photophobia blocked by olcegepant and rizatriptan in a transgenic migraine model.  2009. 

Russo A.  Commentary in News & Analysis, Biobusiness Briefs, Trial Watch. CGRP receptor antagonist meets Phase III migraine end points.  2009. 8(836).

Russo A, Chrissobolis S, Zhang Z, Kinzenbaw D, Faraci F.  Evidence for a Protective Role for Receptor Activity Modifying Protein-1 (RAMP1) in Angiotensin II-Induced Endothelial Dysfunction.  FASEB J.  2009. 23(1017).

Russo A, Marquez de Prado  B, Hammond  D.  Genetic enhancement of calcitonin gene-related peptide-induced central sensitization to mechanical stimuli in mice.  J Pain .  2009. 10:992-1000.
[PubMed]

Russo A, Raddant A, Recober A, Zhang Z, Kaiser E, Kuburas A.  Global hRAMP1 transgene expression leads to an unexpected loss of migraine-like behavior from the nervous system hRAMP1 mice.  2009. 458.

Russo A, Marquez de Prado  B, Hammond D.  Induction of mechanical allodynia by central calcitonin gene-related peptide in a possible migraine model.  J Pain.  2009. 10(S24).

Russo A.  Mice shed light on photophobia and migraine.  Nature Rev Neurology .  2009. 5(465).

Russo A, White S, Marquez de Prado  B, Hammond D.  Nociceptive sensitivity and actions of calcitonin gene related peptide (CGRP) in a mouse model of neurofibromatosis (NF).  2009. 339.

Russo A, Kaiser E, Recober A, Kuburas A, Zhang Z, Walsh S, Thedens D, Boles Ponto  L, Magnotta V, Sunderland J.  Parameters for light aversive behavior and initial neuroimaging studies in a murine migraine model sensitive to CGRP.  2009. 29(1).

Russo A, Park K.  Potential role of distal regulatory elements in ubiquitous induction of the calcitonin/calcitonin gene-related peptide (CALCA) gene in sepsis.  FASEB J.  2009. 23(660).

Russo A, Kaiser E, Recober A, Kuburas A, Zhang Z, Walsh S, Thedens D, Boles Ponto  L, Magnotta V, Sunderland J.  Preliminary neuroimaging and light aversive behavioral parameters using a potential migraine mouse model.  2009. 267.

Russo A.  RAMPing up CGRP in the nervous system: Implications for migraine.  2009. 20(P86).

Russo A, Recober  A, Kuburas  A, Zhang  Z, Wemmie  J, Anderson  M.  Role of calcitonin gene-related peptide in light aversive behavior: implications for migraine.  J Neurosci .  2009. 29:8798-804.
[PubMed]

Russo A.  Scholarship Review.  2009. 
[Link]

Russo A, Regan  J, VanPutte  C.  Seeley’s Essentials of Anatomy and Physiology.  7. McGraw-Hill Higher Education, New York, NY;  2009.

Russo A, Kaiser E, Recober A, Zhang Z, Raddant A.  Targeting CGRP actions in vivo: Neuroimaging and complimentary genetics in a murine migraine model.  2009. 

Russo A, Recober A, Kuburas A, Zhang Z.  A potential migraine model: hRAMP1 transgenic mouse.  2008. 

Russo A, vanOtterloo E, Kaiser E, Kuburas A, Zhang Z.  Can we develop a mouse model for migraine?.  2008. 42(467).

Russo A, Park  K.  Control of the calcitonin gene-related peptide enhancer by upstream stimulatory factor in trigeminal ganglion neurons.  J Biol Chem .  2008. 283:5441-5451.
[PubMed]

Russo A, Recober A, Kuburas A, Zhang Z.  Developing a potential migraine mouse model: hRAMP1 transgenic mice.  2008. 

Russo A, Faraci F, Kinzenbaw D, Lynch C, Zhang Z, Chrissobolis S.  Receptor activity modifying protein-1 (RAMP1) overexpression selectively enhances calcitonin gene-related peptide-induced vasodilation.  FASEB J.  2008. 22(1151).

Russo A.  Potential role for key protein in migraine.  2007 May. 

Russo A, Recober  A.  Advent of a new generation of anti-migraine medications.  Hoboken: John Wiley & Sons, Inc. .  2007. 

Russo A, Seeley  R, Stephens  T, Tate  P.  Anatomy and Physiology.  8. McGraw-Hill Higher Education, New York, NY;  2007.

Russo A, Recober A, Kuburas A, Zhang A.  Developing a potential migraine mouse model.  2007. 71.

Russo A, van Otterloo  E, Kaiser E, Kuburas A, Zhang Z.  Genetic enhancement of CGRP actions: a possible migraine model?.  2007. 27(624).

Russo A, Recober  A.  Olcegepant, a non-peptide CGRP1 antagonist for migraine treatment.  2007. 10:566-574 .
[PubMed]

Russo A, Faraci F, Chrissobolis S, Zhang Z, Lynch C.  Overexpression of receptor activity modifying protein 1 (RAMP1) enhances calcitonin gene-related peptide-induced vasodilation in the cerebral circulation.  FASEB J.  2007. A1384.

Russo A.  Ramping it up: RAMP1 and the implications for migraine.  2007. 8:687-690 .
[PubMed]

Russo A, Faraci F, Chrissobolis S, Zhang z.  Ramping up CGRP functions in RAMP1 transgenic mice.  2007. 523.

Russo A, Zhang  Z, Winborn  C, Marquez de Prado  B.  Sensitization of CGRP receptors by receptor activity-modifying protein-1 in the trigeminal ganglion.  J Neurosci .  2007. 27:2693-2703 .
[PubMed]

Russo A, Park K.  Transcriptional activation of the neuropeptide CGRP by upstream stimulatory factor.  2007. 462.

Russo A.  Research Briefs.  2006 March. 

Russo A, Saadi  I, Toro  R, Kuburas  A, Semina  E, Murray  J.  An unusual class of PITX2 mutations in Axenfeld-Reiger syndrome.  2006. 76:175-181 .
[PubMed]

Russo A, Zhang Z, Dickerson  I.  CGRP receptor activation by RAMP1 gene transfer to vascular smooth muscle cells.  Endocrinology.  2006. 147:1932-1940 .
[PubMed]

Russo A, Marquez de Prado  B.  CGRP receptor antagonists: A new frontier of anti-migraine medications.  2006. 3:593-597.
[PubMed]

Russo A, Dickerson  I.  CGRP: A multifunctional neuropeptide.  Springer, New York, NY.  2006. 

Russo A, Bellamy  J, Bowen  E, Durham  P.  Nitric oxide regulation of calcitonin gene-related peptide gene expression in rat trigeminal ganglia neurons.  Eur J Neurosci .  2006. 23:2057-2066.
[PubMed]

Russo A, Bowen E, Schmidt  T, Firm  C, Durham  P.  Tumor necrosis factor-alpha stimulation of calcitonin gene-related peptide expression and secretion from rat trigeminal ganglion neurons.  J Neurochem .  2006. 96:65-77.
[PubMed]

Russo A, Seboek D, Firm C, Linscheid P, Zulewski H, Keller U, Müller B.  Lentiviral vectors efficiently transduce mature human adipocytes.  2005. 

Russo A, Gagel  R.  Vitamin D control of the calcitonin gene in thyroid C cells.  Elsevier Academic Press, San Diego, CA.  2005. 

Russo A, Trembath  D, Semina  E, Jones  D, Patil  S, Qian  Q, Amendt  B, Murray  J.  Analysis of two translocation breakpoints and identification of a negative regulatory element in patients with Rieger’s syndrome.  2004. 70:82-91.
[PubMed]

Russo A, Toro  R, Saadi  I, Kuburas  A, Nemer  M.  Cell-specific activation of the atrial natriuretic factor promoter by PITX2 and MEF2A.  J Biol Chem .  2004. 279:52087-52094.
[PubMed]

Russo A, Berryman C, Dong P, Marquez DePrado B.  Identification of GABAergic machinery in trigeminal ganglia neurons.  2004. 

Russo A, Berryman C, Dong P, Marquez de Prado B.  Identification of GABAergic Machinery in Trigeminal Ganglia Neurons.  2004. 

Russo A, Durham  P, Dong  P, Belasco  K, Kasperski  J, Gierasch  W, Edvinsson  L, Heistad  D, Faraci  F.  Neuronal expression and regulation of CGRP promoter activity following viral gene transfer into cultured trigeminal ganglia neurons.  2004. 997:103-110.
[PubMed]

Russo A, Viney  T, Schmidt  T, Gierasch  W, Sattar  A, Yaggie  R, Kuburas  A, Quinn  J, Coulson  J.  Regulation of the cell-specific calcitonin/calcitonin gene-related peptide enhancer by USF and the Foxa2 forkhead protein.  J Biol Chem .  2004. 279:49948-49955.
[PubMed]

Russo A, Viney T, Schmidt T, Dong P, Zhang Z, Firm C, Dickerson I, Durham P.  Targeted Regulation of CGRP Gene Expression.  2004. 38(110).

Russo A, Liu  K, Hsiung  S, Adlersberg  M, Franke  T, Gershon  M, Tamir  H.  Calcium receptor-induced serotonin secretion by parafollicular cells: Role of phosphatidylinositol 3-kinase-dependent signal transduction pathways.  J Neurosci.  2003. 23:2049-2057.
[PubMed]

Russo A, Dong P, Durham P.  CGRP and calcium signaling in rat trigeminal ganglia neurons.  2003. 480(7).

Russo A, Kuburas A, Saadi I, Engle J.  Cooperative DNA binding of the PITX2 homeodomain protein.  FASEB J.  2003. 17(A589).

Russo A, Saadi  I, Kuburas  A, Engle  J.  Dominant negative dimerization of a mutant homeodomain protein in Axenfeld-Rieger syndrome.  2003. 23:1968-1982.
[PubMed]

Russo A, Jongeling A, Marquez de Prado B, Kasperski J, Bui J, Dong P, Dickerson I.  Feedback regulation of CGRP release from cultured trigeminal ganglia neurons.  2003. 110(152).

Russo A, Shaw  P, Zhang  X, Amendt  B, Henderson S, Williams  V.  Homeobox protein, Hmx3, in postnatally developing rat submandibular glands.  J Histochem Cytochem.  2003. 51:385-396.
[PubMed]

Russo A, Engle J, Saadi I, Kuburas A.  Identification and characterization of PIASy interaction with the PITX2 homeodomain protein.  FASEB J.  2003. 17(A589).

Russo A, Toro R, Saadi I, Kuburas A.  PITX2 and MEF2A synergistically activate the ANF promoter.  FASEB J.  2003. 17(A591).

Russo A, Dong P, Durham P, Marquez de Prado B.  Regulation of intracellular Ca2+ in trigeminal neurons by an antimigraine drug.  FASEB J.  2003. 17(A607).

Russo A, Durham  P.  Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons.  J Neurosci .  2003. 23:807-815.
[PubMed]

Russo A, Durham P.  Targeted regulation of CGRP: Implications for migraine.  2002 July. 16P.

Russo A, Mora S , Durham  P, Smith  J, Jeromin  A, Pessin  J.  NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase dependent pathway.  J Biol Chem .  2002. 277:27494-27500.
[PubMed]

Russo A, Durham  P.  New insights into the molecular actions of serotonergic anti-migraine drugs.  2002. 94:77-92.
[PubMed]

Russo A, Saadi I, Kuburas A.  PITX2 and MEF2A synergistically activate the ANF promoter.  Am. J. Hum. Genet.  2002. 71(335).

Russo A, Quast B, Billaud M.  Potential therapeutic strategies for medullary thyroid carcinoma.  2002. 103(150).

Russo A, Dong P.  Regulation of intracellular calcium in a neuron-like cell line by 5-HT1 agonists.  2002. 259(16).

Russo A, Durham P.  Stimulation of CGRP secretion from trigeminal ganglia neurons by the TNF-a-sphingosine-ceramide pathway.  2002. 43(16).

Russo A, Tamir H, Liu K, Hsiung S, Adlersberg M, Gershon M.  Transduction pathways of serotonin secretion from parafollicular cells of the thyroid induced by a G-protein-coupled plasmalemmal calcium receptor.  2002. 831(6).

Russo A, Tamir H, Liu K, Hsuing S, Adlersberg M, Gershon M.  5-HT secretion induced by a G-protein coupled receptor (CaR) for extracellular Ca2+.  2001. 27(701.4).

Russo A, Green  P, Hjalt  T, Kirk  D, Sutherland  L, Thomas  B, Amendt  B, Sharpe  P, Snead  M, Murray  J.  Antagonistic regulation of Dlx2 expression by PITX2 and Msx2: Implications for tooth development.  2001. 9:265-281.
[PubMed]

Russo A, Wood  J.  Autoregulation of cell-specific MAP kinase control of the tryptophan hydroxylase promoter.  J Biol Chem .  2001. 276:21262-21271.
[PubMed]

Russo A, Toro R, Saadi I, Jin Y, Condie B.  Characterization of PITX2 Rieger syndrome mutations in C. elegans.  Am. J. Hum. Genet.  2001. 69(1038).

Russo A, Saadi  I, Semina  E, Amendt  B, Harris  D, Murphy  K, Murray  J.  Identification of a dominant negative homeodomain mutation in Rieger syndrome.  J Biol Chem.  2001. 276:23034-23041.
[PubMed]

Russo A, Saadi I, Kuburas A.  Molecular characterization of a Rieger syndrome nonsense mutation in PITX2.  Am. J. Hum. Genet.  2001. 69(1099).

Russo A, Kuburas A, Saadi I.  PITX2 homeodomain protein forms a dimer: Insights from natural and synthetic mutations.  Am. J. Hum. Genet.  2001. 69(1090).

Russo A, Durham P.  Regulation of CGRP gene expression in primary trigeminal ganglia neurons by nitric oxide.  2001. 27(477.17).

Russo A, Durham B.  Targeted regulation of CGRP gene expression.  Scientific World Journal .  2001. 1(5).

Russo A, Faraci F, Heistad D, Durham P.  Targeted regulation of CGRP neuropeptide levels: Potential for neurovascular gene therapy.  2001. 97(65).

Russo A, Rind  H, Whittemore  S.  Developmental regulation of the tryptophan hydroxylase gene.  2000. 101:181-193.
[PubMed]

Russo A, Durham  P.  Differential regulation of mitogen-activated protein kinase-responsive genes by the duration of a calcium signal.  2000. 14:1570-1582.
[PubMed]

Russo A, Toyoda  K, Faraci  F, Davidson  B, Heistad  D.  Gene transfer of calcitonin gene-related peptide to cerebral arteries.  Am J Physiol (Heart Circ Physiol).  2000. 278:H586-594.
[PubMed]

Russo A, Saadi I, Semina E, Harris D, Murphy K, Murray J.  Identification of a dominant negative Rieger syndrome mutation in PITX2.  Am. J. Human Genetic.  2000. 67(188).

Russo A, Saadi I, Toro R, Condie B.  Molecular characterization of PITX2 mutations in non-neuronal and neuronal cells.  2000. 26(608.4).

Russo A, 30. Durham P.  Regulation of calcium levels by 5-HT1 receptor activation: Implications for migraine therapy.  2000. 26(145.13).

Russo A, Durham P.  Regulation of CGRP gene expression: Or how to get a headache.  2000. 86(20).

Russo A, Rind H, Whittemore S.  Developmental regulation of TPH mRNA expression and enzyme activity in the raphe and its target fields: evidence for postnatal raphe neuronal death?.  1999. 25(516).

Russo A, Toyoda K, Faraci F, Davidson B, Heistad D.  Gene transfer of calcitonin gene-related peptide alters reactivity of cerebral arteries.  1999. 30(239).

Russo A, Durham P.  Inhibition of neuropeptide gene expression by sustained elevation of intracellular calcium.  1999. 25(1810).

Russo A, Saadi I, Murphy K.  Molecular characterization of a Rieger syndrome mutation in PITX2.  Am. J. Human Genetic .  1999. 65(A379).

Russo A, Amendt  B, Sutherland  L.  Multifunctional role of the Pitx2 homeodomain protein C-terminal tail.  1999. 19:7001-7010.
[PubMed]

Russo A, Durham  P.  Regulation of calcitonin gene-related peptide secretion by a serotonergic antimigraine drug.  J Neurosci .  1999. 19:3423-3429.
[PubMed]

Russo A, Amendt  B, Sutherland  L.  Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site.  J Biol Chem.  1999. 274:11635-11642.
[PubMed]

Russo A, Siuciak  J, Clark  M, Rind  H, Whittemore  S.  BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain.  J Neurosci Res .  1998. 52:149-158.
[PubMed]

Russo A, Belasco K, Toyoda K, Faraci F, Davidson B, Durham P, Heistad D.  Expression of calcitonin gene-related peptide following adenovirus-mediated gene transfer to COS cells.  FASEB J. .  1998. 12(A674).

Russo A, Lanigan T, Qian X.  Identification of a protein kinase that interacts with nuclear receptors.  1998. 80:477-478 .

Russo A, Durham P.  Inhibition of CGRP secretion by 5-HT1 antimigraine drugs.  1998. 24(772).

Russo A, Clark  M.  Measurement of tryptophan hydroxylase mRNA levels by competitive RT-PCR.  1998. 2:273-285.
[PubMed]

Russo A.  Neuronal differentiation of cranial-crest derived thyroid C-cells.  CRC Press, Boca Raton, FL .  1998. 

Russo A, Lanigan  T, DeRaad  S.  Requirement of the MASH-1 transcription factor for neuroendocrine differentiation of thyroid C cells.  J Neurobiol .  1998. 34:126-134.
[PubMed]

Russo A, Durham P.  Serotonergic repression of MAP kinase control of the CGRP enhancer.  1998. 80(343).

Russo A, Durham  P.  Serotonergic repression of mitogen-activated protein kinase control of the calcitonin gene-related peptide enhancer.  1998. 12:1002-1009.
[PubMed]

Russo A, Amendt B, Sutherland L, Murray J.  The molecular basis of Rieger syndrome: Analysis of Pitx2 homeobox activities.  1998. 80(111).

Russo A, Amendt  B, Sutherland  L, Semina  E.  The molecular basis of Rieger syndrome: Analysis of Pitx2 homeodomain protein activities.  J Biol Chem .  1998. 273:20066-20072.
[PubMed]

Russo A, Lanigan  T.  Binding of upstream stimulatory factor and a cell-specific activator to the calcitonin/calcitonin gene-related peptide enhancer.  J Biol Chem .  1997. 272:18316-18324.
[PubMed]

Russo A, Amendt B, Sutherland L, Semina E, Murray J.  Characterization of Solurshin, a novel bicoid homeobox transcription factor involved in Reiger syndrome.  1997. 79(565).

Russo A, Lanigan T.  Combinatorial control of the calcitonin/CGRP enhancer by the USF helix-loop-helix protein and a cell-specific coactivator.  1997. 79(565).

Russo A, Durham  P, Sharma  R.  Repression of the calcitonin gene-related peptide promoter by 5-HT1 receptor activation.  J Neurosci .  1997. 17:9545-9553.
[PubMed]

Russo A, Durham P.  Serotonergic repression of calcitonin gene-related peptide gene expression.  1997. 79(568).

Russo A, Durham P.  Serotonergic repression of calcitonin gene-related peptide gene expression: Elucidation of molecular mechanism.  1997. 23(1670).

Russo A, Clark  M.  Tissue-specific glucocorticoid regulation of tryptophan hydroxylase mRNA levels.  1997. 48:346-354.
[PubMed]

Russo A, Clark M.  Cell-specific glucocorticoid regulation of tryptophan hydroxylase mRNA levels in the brain.  1996. 22(1442).

Russo A, Tamir  H, Hsiung  S, Liu  K, Blakely  R, Clark  M, Nunez  E, Gershon  M.  Expression and development of a functional plasmalemmal 5-hydroxytryptamine transporter by thyroid follicular cells.  1996. 137:4475-4486.
[PubMed]

Russo A, Tamir H, Liu K, Hsuing S, Blakely R, Clark M, Gershon M.  Expression, function, and development of a 5-HT transporter (SERT) in the plasma membrane of thyroid follicular cells.  1996. 22(615).

Russo A, Lanigan  T.  Neuronal properties of thyroid C-cell tumor lines.  Landes Co., Austin, TX .  1996. 

Russo A, Lanigan T.  Role of MASH-1 in thyroid C cell differentiation and gene expression.  1996. 22(28).

Russo A, Durham P, Pantazis N.  Serotonergic repression of calcitonin gene-related peptide gene expression.  1996. 22(1592).

Russo A, Durham  P, Clark  M.  Thyroid parafollicular cells: An accessible model for the study of serotonergic neurons.  1996. 13:257-276.
[PubMed]

Russo A, Green  S.  Editorial: Neuronal cell lines.  1995. 7:219-221.

Russo A, Clark  M, Lanigan  T, Page  N.  Induction of a serotonergic and neuronal phenotype in thyroid C-cells.  J Neurosci .  1995. 15:6167-6178.
[PubMed]

Russo A.  Retinoids: From basic science to clinical applications. Molecular and cell biology updates.  1995. 70(542).

Russo A, Clark  M, Lanigan  T.  Serotonergic neuronal properties in C-cell lines.  1995. 7:253-261.

Russo A.  Calcitonin gene-related peptide. The first decade of a novel pleiotropic neuropeptide.  1994. 84(127).

Russo A, Michalchik M.  Characterization of the extracellular calcium receptor in rat thyroid C-cells.  1994. 20(67).

Russo A, Tompach P, Daniels K.  Construction of a cranial neural crest cDNA library.  J. Oral Maxillofac. Surg. .  1994. 52(158).

Russo A, Johnson W, Clark M.  Dexamethasone repression of tryptophan hydroxylase mRNA levels in the CA77 C-cell line.  1994. 20(289).

Russo A.  Neurotrophic factors .  1994. 93:480-481.

Russo A, Crawford  J, Mutchler  K, Sullivan  B, Lanigan  T, Clark  M.  Neural expression of a novel alternatively spliced and polyadenylated Gsa transcript.  J Biol Chem .  1993. 268:9879-9885.
[PubMed]

Russo A, Tverberg L.  Neuroendocrine-specific transcription of the calcitonin/CGRP gene involves synergy between an HLH factor and an associated factor.  J. Cellul. Biochem.  1993. 17D(267).

Russo A, Tverberg  L.  Regulation of the calcitonin/calcitonin gene-related peptide gene by cell-specific synergy between helix-loop-helix and octamer-binding transcription factors.  J Biol Chem .  1993. 268:15965-15973.
[PubMed]

Russo A, Lanigan  T, Tverberg  L.  Retinoic acid repression of cell-specific helix-loop-helix-octamer activation of the calcitonin/calcitonin gene-related peptide enhancer.  1993. 13:6079-6088.
[PubMed]

Russo A, Mutchler  K, Klemish  S.  A rapid PCR protocol for identification of differentially expressed genes from a cDNA library.  1992. 1:195-198.
[PubMed]

Russo A, Tverberg  L.  Cell-specific glucocorticoid repression of calcitonin/calcitonin gene-related peptide transcription: Localization to an 18-base pair basal enhancer element.  J Biol Chem .  1992. 267:17567-17573.
[PubMed]

Russo A, Chen  Y, Huang L, Solursh M.  Hensen’s node is a source of retinoic acid in the early chick embryo.  Anatomical Rec.  1992. 232(19a).

Russo A, Lanigan  T, Sullivan  B.  Neuronal properties of a thyroid C-cell line: Partial repression by dexamethasone and retinoic acid.  1992. 6:207-218.
[PubMed]

Russo A, Chen Y, Huang  L, Solursh  M.  Retinoic acid is enriched in Hensen's node and is developmentally regulated in the early chick embryo.  1992. 89:10056-10059.
[PubMed]

Russo A, Crenshaw  E, Swanson  L, Rosenfeld  M.  Transgenic Mouse Technology: Application to the Study of the Nervous System.  Elsevier.  1992. 

Russo A, Chamany  K, Klemish  S, Hall  T, Murray  J.  Characterization of the calcitonin/CGRP gene in Williams Syndrome.  Am J Med Genet .  1991. 39:28-33.
[PubMed]

Russo A, Tverberg L.  Glucocorticoid regulation of the calcitonin/CGRP gene in transfected cell lines.  1991. 

Russo A, Soulati A, Tverberg L.  Cell-specific glucocorticoid regulation of calcitonin/CGRP gene expression.  1990. 

Russo A, Li  S, Klein  E, Simmons  D, Rosenfeld  M.  Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities.  1989. 86:9778-9782.
[PubMed]

Russo A, Nelson  C, Roos  B, Rosenfeld  M.  Differential regulation of the coexpressed calcitonin/a-CGRP and b-CGRP neuroendocrine genes.  J Biol Chem .  1988. 263:5-8.
[PubMed]

Russo A, Crenshaw III E, Lira  S, Simmons  D, Swanson  L, Rosenfeld  M.  Neuronal expression of chimeric genes in transgenic mice.  1988. 1:311-320.
[PubMed]

Russo A, Rosenfeld  M, Crenshaw 3rd E, Emeson  R, Leff  S, Guise  J, Lira  , Nelson C.  Transcriptional and post-transcriptional strategies in neuroendocrine gene expression.  1988. 5:317-334.
[PubMed]

Russo A, Leff  S, Evans  R, Rosenfeld  M.  Alternative RNA processing events in calcitonin/CGRP gene expression: A strategy for developmental regulation of neuroendocrine gene expression.  Japan Scientific Societies Press.  1987. 

Russo A, Rosenfeld  M, Leff  S, Crenshaw  E, Ahearn  K.  Developmental control of a calcium-regulating neuroendocrine gene.  Academic Press, San Diego, CA.  1987. 

Russo A, Lin  C, Kapiloff  M, Durgerian  S, Tatemoto  K, Hanson  P, Schulman  H, Rosenfeld  M.  Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase.  1987. 84:5962-5966.
[PubMed]

Russo A, Rosenfeld  M, Leff  S, Evans  R.  Neuron-specific alternative RNA processing in neuroendocrine gene expression.  1987. 15:128-131.
[PubMed]

Russo A, Crenshaw E, Rosenfeld  M.  Neuron-specific alternative RNA processing in transgenic mice.  J. Cellular Biochem.  1987. 11D(181).

Russo A, Crenshaw III E, Swanson  L, Rosenfeld  M.  Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene.  1987. 49:389-398.
[PubMed]

Russo A, Rosenfeld  M, Leff  S, Crenshaw  E, Nelson  C, Franco  R, Lira  S, Evans  R.  Regulation of neuroendocrine gene expression.  1987. 52:369-378.

Russo A, Koshland Jr. D.  Identification of the tip-encoded receptor in bacterial sensing.  J Bacteriol .  1986. 165:276-282.
[PubMed]

Russo A, Leff  S, Nelson  C, Crenshaw  E, Elsholtz  H, Mangalam  H, Evans  R, Rosenfeld  M.  Transcriptional and post-transcriptional regulation of neuroendocrine gene expression.  ICSU Short Reports.  1986. 4:6-9.

Russo A, Rosenfeld  M, Leff  S, Evans  R.  Transcriptional control of neuroendocrine genes.  1986. 

Russo A, Koshland Jr  D.  Receptor modification and absolute adaptation in bacterial sensing.  Elsevier Science Publishers, New York.  1985. 

Russo A, Aline Jr. R, Reeves C, Volcani B.  Role of silicon in diatom metabolism: Cyclic nucleotide levels, nucleotide cyclase, and phosphodiesterase activities during synchronized growth of Cylindrotheca fusiformis.  1984. 76:674-679.
[PubMed]

Russo A, Gutterson  N, Koshland Jr D.  Information processing in a sensory system.  1983. 48:805-810.
[PubMed]

Russo A, Koshland Jr. D.  Separation of signal transduction and adaptation functions of the aspartate receptor in bacterial sensing.  1983. 220:1016-1020.
[PubMed]

Russo A, Koshland Jr.  D.  Structure-function relationships of the chemotaxis aspartate receptor.  1983. 42(2136).

Russo A, Koshland Jr.  D, Wang E, Clegg  D.  Evolution of receptors in bacterial chemotaxis. (UCLA Symposia).  J. Cellular Biochemistry .  1982. 6(174).

Russo A, Recober  A, Zhang  Z, Marquez de Prado  B, Kaiser  E, Kuburas  A.  Biological relevance of CGRP in the context of migraine.  Oxford University Press; 

Russo A, Kuburas  A, Saadi  I, Russo  E, Pelletier  L, Manie  S, Billaud  M.  Identification of a novel Ret mutation in a neuronal-like medullary thyroid carcinoma. 

Russo A, Wang  J, Saadi  I, Wang  J, Engle  J, Kuburas  A, Amendt  B.  PIAS1 and PIASy differentially regulate PITX2 transcriptional activity independent of sumoylation. 

Date Last Modified: 06/07/2014 - 21:56:23