Neurology

Matthew Gillum, PhD

Portrait

Specialty: Cellular and Molecular Physiology
Research Assistant Professor of Neurology

Contact Information

Primary Office: 1000 ML
Iowa City, IA 52242
Primary Office Phone: 319-356-8757

Email: matthew-gillum@uiowa.edu

Education

BS, Biology, Duke University
PhD, Cellular and Molecular Physiology, Yale University

Research Summary

The physiology of lipid neurotransmitters

All Publications

KOTAS M, GORECKI M, Gillum M.  Sirtuin-1 is a nutrient-dependent modulator of inflammation.  Adipocyte.  2013. 2(2).

Erion D, Popov V, Hsiao J, Vatner D, Mitchell K, Yonemitsu S, Nagai Y, Kahn M, Gillum M, Dong J, Murray S, Manchem V, Bhanot S, Cline G, Shulman G, Samuel V.  The role of the carbohydrate response element-binding protein in male fructose-fed rats..  Endocrinology.  2013 January. 154(1):36-44.
[PubMed]

Brown W, Gillum M, Lee H, Camporez J, Zhang X, Jeong J, Alves T, Erion D, Guigni B, Kahn M, Samuel V, Cravatt B, Diano S, Shulman G.  Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism..  Proceedings of the National Academy of Sciences of the United States of America.  2012 September. 109(37):14966-71.
[PubMed]

Gillum M, Kotas M, Erion D, Kursawe R, Chatterjee P, Nead K, Muise E, Hsiao J, Frederick D, Yonemitsu S, Banks A, Qiang L, Bhanot S, Olefsky J, Sears D, Caprio S, Shulman G.  SirT1 regulates adipose tissue inflammation..  Diabetes.  2011 December. 60(12):3235-45.
[PubMed]

SRISAI D, Gillum M, PANARO B, ZHANG X, KOTCHABHAKDI N, SCHULMAN G, ELLACOTT K, CONE R.  Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse.  Endocrinology.  2011. 152(3).
[PubMed]

KOTAS M, LEE H, Gillum M, ANNICELLI C, CUIGNI B, SCHULMAN B,  M.  Impact of CD1d deficiency on metabolism.  PLoS One;  2011. 

Kotas M, Lee H, Gillum M, Annicelli C, Guigni B, Shulman G, Medzhitov R.  Impact of CD1d deficiency on metabolism..  PloS one.  2011. 6(9):e25478.
[PubMed]

Gillum M, KOTAS M, ERION D, KURSAWE R, CHATTERJEE P, NEAD K, MUISE E, HSIAO J, FREDERICK D, YONEMITSU S, BANKS A, QUIANG L, BHANOT S, OLEFSKY J, SEARS D, CAPRIO S, SCHULMAN G.  SirT1 regulates adipose tissue inflammation.  Diabetes.  2011. 60(12):3235-3245.
[PubMed]

Gillum M, ERION D, SCHULMAN G.  Sirtuin-1 regulation of mammalian metabolism.  Trends in Molecular Medicine.  2011. 17(1):8-13.

Gillum M, Erion D, Shulman G.  Sirtuin-1 regulation of mammalian metabolism..  Trends in molecular medicine.  2010 October. 
[PubMed]

Erion D, Yonemitsu S, Nie Y, Nagai Y, Gillum M, Hsiao J, Iwasaki T, Stark R, Weismann D, Yu X, Murray S, Bhanot S, Monia B, Horvath T, Gao Q, Samuel V, Shulman G.  SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats..  Proceedings of the National Academy of Sciences of the United States of America.  2009 July. 106(27):11288-93.
[PubMed]

ERION D, YONEMITSU S, NIE Y, NAGAI Y, Gillum M, HSIAO J, IWASAKI T, STARK R, WEISMANN E, YU X, MURRAY S, BHANOT S, MONIA B, HORVATH T, GAO Q, SAMUEL V, SCHULMAN G.  Knockdown of SirT1 expression in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.  PNAS.  2009. 106:11288-11293.
[PubMed]

Gillum M, Zhang D, Zhang X, Erion D, Jamison R, Choi C, Dong J, Shanabrough M, Duenas H, Frederick D, Hsiao J, Horvath T, Lo C, Tso P, Cline G, Shulman G.  N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake..  Cell.  2008 November. 135(5):813-24.
[PubMed]

Gillum M, ZHANG D, ZHANG X, ERION D, JAMISON R, CHOI C, DONG J, SHANABROUGH M, DUENAS H, FREDERICK D, HSIAO J, HORVATH T, LO C, TSO P, CLINE G, SCHULMAN G.  N-acylphosphatidylethanolamine, a gut derived circulating factor induced by fat ingestion, inhibits food intake.  Cell.  2008. 135(5):813-824.
[PubMed]

Neschen S, Morino K, Rossbacher J, Pongratz R, Cline G, Sono S, Gillum M, Shulman G.  Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice..  Diabetes.  2006 April. 55(4):924-8.
[PubMed]

NESCHEN S, MORINO J, ROSSBACHER J, PONGRATZ R, CLINE G, SONO S, Gillum M, SCHULMAN G.  Fish oil regulates adiponectin secretion by a peroxisome proliferator gamma-dependent mechanism in mice.  Diabetes.  2006. 55(4):924-928.
[PubMed]

Gillum M, ERION D, KOTAS M, CHARTERJEE P, NEAD K, HSIAO J, YONEMITSU S, SHULMAN G.  Physiologic reduction of SirT1 expression reproduces obesity-associated inflammation and adipose tissue macrophage accumulation.  Diabetes. 

Gillum M, HARRIS-BROWN W, ERION D, SHULMAN G.  Physiologic stimulation of gut incretin GLP-1 secretion by N-acylphosphatidylethanolamine activation of Gpr119. 

KOTAS M, JURCZAK M, ANNICELLI C, Gillum M, CLINE G, SHULMAN G, MEDZHITOV R.  Role of caspase-1 in regulation of triglyceride metabolism.  PNAS. 

Date Last Modified: 06/07/2014 - 21:56:23