Microbiology

Gail A. Bishop, PhD

Portrait

Holden Chair of Cancer Biology
College of Medicine Distinguished Professor of Microbiology
Co-Director, Cancer Immunology & Immunotherapy Group
Associate Director for Basic Science Research
Professor of Microbiology
Professor of Internal Medicine

Contact Information

Office: 2193B Medical Education and Research Facility
375 Newton Rd
Iowa City, IA 52242
Office Phone: 319-335-7945

Lab: 2219 Medical Education and Research Facility
375 Newton Rd
Iowa City, IA 52242
Phone: 319-335-7816

Email: gail-bishop@uiowa.edu
Web: Bishop Lab Website

Education

BA, Biology, St Olaf College
MS, Oncology, University of Wisconsin, Madison
PhD, Cellular and Molecular Biology, University of Michigan, Ann Arbor

Post Doctoral, Immunology, The University of North Carolina, Chapel Hill
Post Doctoral, Immunology, The University of North Carolina, Chapel Hill

Education/Training Program Affiliations

Biosciences Graduate Program
Department of Microbiology Graduate Program
Interdisciplinary Graduate Program in Immunology
Interdisciplinary Graduate Program in Molecular and Cellular Biology
Interdisciplinary Graduate Program in Translational Biomedicine
Medical Scientist Training Program

Research Summary

Bishop Lab - Current Projects

We are interested in the molecular mechanisms which underlie the processes of lymphocyte activation and tolerance. Our particular areas of current focus are in lymphocyte signaling and interactions between innate and adaptive immune receptors.

The following is a summary of key projects ongoing in the lab –

1) How does TRAF3 regulate survival uniquely in B lymphocytes? How can this information be used to select more effective treatments for B cell malignancies?

Members of the tumor necrosis factor receptor (TNFR) superfamily participate in a large number of events that regulate cell activation and programmed cell death. A substantial majority of signals induced by receptors of this family are delivered via cytoplasmic (CY) adapter molecules belonging to the TNFR-associated factor (TRAF) family. It is now clear from work performed by our group and others during the past several years that TRAF3 can play diverse, even sharply contrasting roles in signaling by different receptors. Although whole-mouse deficiency in TRAF3 is lethal, we produced a conditional TRAF3-deficient mouse strain that permits us to assess the functions of TRAF3 in distinct cell types. Mice lacking TRAF3 specifically in B cells show dramatically increased B cell survival, with normal cell proliferation. This results in massively enlarged secondary lymphoid organs, autoantibody production and lymphoid infiltration of major organs, and development of B cell tumors as mice age. We have to date produced mice lacking TRAF3 in B lymphocytes, T lymphocytes, and dendritic cells. In all these cell types, TRAF3 deficiency results in constitutive activation of the ‘noncanonical’ or “NF-kB2” signaling pathway. However, although current dogma suggests that this explains the remarkably prolonged survival of TRAF3-deficient B cells, we found that NF-kB2 activation correlates with enhanced survival ONLY in B cells, and does not confer changes in survival on T cells or dendritic cells. This is consistent with the association of loss-of-function mutations in TRAF3 observed with B cell malignancies in humans, but not tumors in other cell types. We are thus investigating the molecular mechanisms by which TRAF3 deficiency regulates cell survival uniquely in B lymphocytes. This information could permit greater efficacy in designing treatments for B cell malignancies, as it can inform the targeting of non-proliferating cells that could survive standard chemotherapy.

2) What is the role of TRAF3 in signaling and function of T cells?

We also produced mice that lack TRAF3 specifically in T cells. Unlike B cells, TRAF3-deficient T cells have no alterations in survival. Instead, we found that these T cells show marked decreases in CD4+ and CD8+ T cell function to infection and immunization. Additionally, invariant NK T cell development and function are severely compromised in these mice, in a manner attributable to the reduced TCR signaling and upregulation of the transcription factor T-bet. In the absence of TRAF3, signaling through the TCR is compromised from the earliest measurable event, the activation of Src kinases. We also found that TRAF3 associates with the TCR complex. We are currently using multiple investigative strategies to explore this association, and how TRAF3 normally promotes TCR signaling and function. Key to this process appears to be blocking by TRAF3 of association with the TCR of the Src kinase inhibitor Csk. We are also investigating how TRAF3 regulates signaling through the IL-2 receptor by association with Jak molecules and the T cell phosphatase TCPTP. This regulation restrains IL-2 responses of thymic T regulatory cell precursors, and in the absence of T cell TRAF3, mice have an increased number of nTreg cells with elevated IL-2 responses.

3) Approaches to the design of better vaccination strategies.

The global human population is developing an increasing need for new and better vaccines, to combat both infectious and malignant disease. A limiting factor in human vaccine development has been the narrow selection of safe adjuvants, to increase the effectiveness of vaccines, and stimulate effective responses with fewer immunizations. Scientists have made tremendous advances in understanding how the components of adjuvants, distinct pathogen-associated molecular patterns (PAMPs), trigger specific receptors of the innate immune system. Of particular interest are ligands for receptors that recognize special features of viral or bacterial nucleic acids, as these ligands can be readily produced synthetically, without the safety concerns associated with purifying substances from large quantities of infectious microbes. This project focuses on gaining a more complete understanding of how receptors for microbial nucleic acids interact with receptors of the adaptive immune system in the activation of B lymphocytes, with the long-term goal of applying this knowledge to better strategies in vaccine development. B cells are now appreciated to play important roles in cytokine production and antigen presentation, and are highly TLR-responsive. What are the effects of interactive signals between adaptive and innate receptors on the function of B cells as antigen-presenting cells (APC)? We hypothesize that interactions between these receptor types will enhance the APC ability of B lymphocytes. This information will allow design of vaccines that maximize the efficacy of B cell activation, not only to produce antibodies and cytokines, but also to activate cellular responses as APC. Our findings to date show that B cell vaccines offer a viable alternative to dendritic cell vaccines in efficacy, and are much easier to obtain from the host and to manipulate in vitro. We are currently optimizing the stimuli used in B cell vaccination, and applying this information to vaccination in a melanoma tumor model.

4) Understanding the protective role of CD40 in diet-induced obesity.

We have studied the immune cell costimulatory signaling receptor CD40 for many years. We recently noticed that our colony of CD40 knockout (CD40KO) mice tend to become quite large as they pass mouse ‘middle age’. Upon further investigation, we discovered that they also have elevated blood glucose and decreased serum insulin. We embarked upon an initial set of studies to examine the role of CD40 in high-fat diet (HFD)-induced obesity (DIO). CD40KO mice gain significantly more weight on a HFD, and develop fatty livers, with both glucose and insulin intolerance. There is marked infiltration of macrophages and CD8+ T cells into the visceral adipose, but not the subcutaneous adipose tissue. The exacerbated DIO of CD40KO mice can be transferred to recipient mice with just CD8+ T cells, and requires TNF. These T cells express CD40 and also produce several chemokines at elevated levels. Current studies seek to understand the specific mechanisms by which CD40 protects against DIO normally, and how CD40 function in the intestinal immune system regulates the microbiota of the intestinal environment.

Center, Program and Institute Affiliations

Cardiovascular Research Center
Center for Immunology and Immune-based Diseases
Center on Aging
Fraternal Order of Eagles Diabetes Research Center
Helen C. Levitt Center for Viral Pathogenesis
Holden Comprehensive Cancer Center
Institute for Clinical and Translational Science
Stephen A. Wynn Institute for Vision Research

All Publications

Yi Z, Lin W, Stunz L, Bishop G.  The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.  Nat Immunol.  2014 September. 15(9):866-74.
[Link]

Yi Z, Stunz L, Bishop G.  CD40-mediated maintenance of immune homeostasis in the adipose tissue microenvironment.  Diabetes.  2014 August. 63(8):2751-60.
[Link]

Bishop G.  Introduction to immunology at The University of Iowa.  Immunol Res.  2014 August. 59(1-3):1-2.
[Link]

Buchta C, Bishop G.  Toll-like receptors and B cells: functions and mechanisms.  Immunol Res.  2014 August. 59(1-3):12-22.
[Link]

Yi Z, Stunz L, Lin W, Bishop G.  TRAF3 regulates homeostasis of CD8+ central memory T cells.  PLoS One.  2014 July 10. 9(7):e102120.
[Link]

Yi Z, Lin W, Stunz L, Bishop G.  Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions.  Cytokine Growth Factor Rev.  2014 April. 25(2):147-56.
[Link]

Arcipowski K, Stunz L, Bishop G.  TRAF6 is a critical regulator of LMP1 functions in vivo.  Int Immunol.  2014 March. 26(3):149-58.
[Link]

Ontiveros E, Halwani A, Stunz L, Kamberos N, Olivier A, Janz S, Bishop G.  A new model of LMP1-MYC interaction in B cell lymphoma.  Leuk Lymphoma.  2014. Epub ahead of print.
[Link]

Stunz L, Bishop G.  B cell functions of LMP1.  Immunol Rev.  2014. 

Stunz L, Bishop G.  Latent membrane protein 1 and the B lymphocyte-a complex relationship.  Crit Rev Immunol.  2014. 34(3):177-98.
[Link]

Buchta C, Bishop G.  TRAF5 Negatively Regulates TLR Signaling in B Lymphocytes.  J Immunol.  2014 January 1. 192(1):145-50.
[Link]

Jenkinson S, Williams J, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop G, Hollander G, Takahama Y, Hodes R.  TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.  Proc Natl Acad Sci U S A.  2013 December 24. 110(52):21107-12.
[Link]

Lin W, Hildebrand J, Bishop G.  A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes.  Front Immunol.  2013 December 20. 4:477.
[Link]

Jellusova J, Miletic A, Cato M, Lin W, Hu Y, Bishop G, Shlomchik M, Rickert R.  Context-Specific BAFF-R Signaling by the NF-κB and PI3K Pathways.  Cell Rep.  2013 November 27. 5(4):1022-35.
[Link]

Hostager B, Bishop G.  CD40-Mediated Activation of the NF-κB2 Pathway.  Front Immunol.  2013 November 15. 4:376.
[Link]

Wallis A, Yi Z, Bishop G.  TRAF3 regulates CSK to enhance TCR signaling.  Autumn Immunology Conference, Chicago, IL.  2013 November. 

Mambetsariev N, Stunz L, Lin W, Bishop G.  TRAF3- a novel regulator of CREB transcription factor in B cells.  Autumn Immunology Conference, Chicago, IL.  2013 November. 

Buchta C, Bishop G.  TRAF5 negatively regulates TLR signaling via inhibition of TAB function in B cells.  Autumn Immunology Conference, Chicago, IL.  2013 November. 

Bishop G.  The many faces of TRAF molecules in immune regulation.  J Immunol.  2013 October 1. 191(7):3483-5.
[Link]

Han S, Tompkins V, Son D, Kamberos N, Stunz L, Halwani A, Bishop G, Janz S.  Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells.  Biochem Biophys Res Commun.  2013 July 12. 436(4):660-5.
[Link]

Yi Z, Stunz L, Bishop G.  TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells.  J Exp Med.  2013 June 3. 210(6):1079-86.
[Link]

Munroe M, Anderson J, Gross T, Stunz L, Bishop G, James J.  EBV CD40 functional mimic LMP1 drives cellular molecular mimicry in the presence of EBNA-1 in a novel murine model of lupus-like disease.  American Association of Immunologists, Honolulu, HI.  2013 May. 

Stunz L, LeBeau R, Bishop G.  LMP1 signaling in vivo downregulates DUSP1 and exacerbates inflammatory responses.  American Association of Immunologists, Honolulu, HI.  2013 May. 

Lin W, Stunz L, LeBeau R, Mambetsariev N, Bishop G.  The role of TRAF3 in B cell-specific regulation of survival and malignancy.  American Association of Immunologists, Honolulu, HI.  2013 May. 

Yi Z, Lin W, Stunz L, Bishop G.  TRAF3 restrains regulatory T cell development by modulating the IL-2 signaling pathway.  American Association of Immunologists, Honolulu, HI.  2013 May. 

Buchta C, Bishop G.  TRAF5 negatively regulates TLR signaling.  American Association of Immunologists, Honolulu, HI.  2013 May. 

Arcipowski K, Bishop G.  TRAF6 as a critical regulator of B lymphocyte functions.  Curr Top Immunol.  2013. 14:45-52.

Arcipowski K, Bishop G.  TRAF Binding Is Required for a Distinct Subset of In Vivo B Cell Functions of the Oncoprotein LMP1.  J Immunol.  2012 December 1. 189(11):5165-70.
[Link]

Lin W, Hildebrand J, Bishop G.  The complex relationship between TRAF3 and B cell functions.  Autumn Immunology Conference, Chicago, IL.  2012 November. 

Buchta C, Bishop G.  TRAF5 negatively regulates TLR signaling.  Autumn Immunology Conference, Chicago, IL.  2012 November. 

Poovassery J, Bishop G.  Type I IFN receptor and the B cell antigen receptor regulate TLR7 responses via distinct molecular mechanisms.  J Immunol.  2012 August 15. 189(4):1757-64.
[Link]

Buchta C, Bishop G.  Roles of TRAF5 in TLR signaling.  American Association of Immunologists, Boston, MA.  2012 May. 

Lin W, Hildebrand J, Bishop G.  The complex relationship between TRAF3 and B cell function.  American Association of Immunologists, Boston, MA.  2012 May. 

Bishop G.  The power of monoclonal antibodies as agents of discovery: CD40 Revealed as a B lymphocyte costimulator.  J Immunol.  2012 May 1. 188(9):4127-9.
[Link]

Arcipowski K, Bishop G.  Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1.  PLoS One.  2012. 7(7):e42478.
[Link]

Xie P, Poovassery J, Stunz L, Smith S, Schultz M, Carlin L, Bishop G.  Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes.  J Leukoc Biol.  2011 December. 90(6):1149-57.
[Link]

Lin W, Halwani A, Bishop G.  Effects of a multiple myeloma-associated TRAF3 mutation on B cell signaling pathways.  Autumn Immunology Conference, Chicago, IL.  2011 November. 

Vanden Bush T, Bishop G.  Exploiting pre-existing humoral responses to enhance immune responses to new antigens.  Autumn Immunology Conference, Chicago, IL.  2011 November. 

Yi Z, Stunz L, Bishop G.  Intrinsic effects of TRAF3 on iNKT cell development and function.  Autumn Immunology Conference, Chicago, IL.  2011 November. 

Buchta C, Bishop G.  Roles of TRAF5 in TLR signaling.  Autumn Immunology Conference, Chicago, IL.  2011 November. 

Hildebrand J, Yi Z, Buchta C, Poovassery J, Stunz L, Bishop G.  Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions.  Immunol Rev.  2011 November. 244(1):55-74.
[Link]

Decker D, Bishop G.  Characterization of the indirect role of TRAF6 in CD40 signaling.  13th International TNF Conference, Awaji, Japan.  2011 May. 

Arcipowski K, Stunz L, Poovassery J, Bishop G.  Multiple functions for TRAFs in immune regulation.  13th International TNF Conference, Awaji, Japan.  2011 May. 

Yi Z, Stunz L, Bishop G.  Roles of TRAF3 in TCR signaling.  American Association of Immunologists, San Francisco, CA.  2011 May. 

Poovassery J, Bishop G.  Type I IFN-mediated reversal of TLR tolerance in antigen presenting cells.  American Association of Immunologists, San Francisco, CA.  2011 May. 

Vanden Bush T, Bishop G.  CDK-mediated regulation of cell functions via c-Jun phosphorylation and AP-1 activation.  PLoS One.  2011 April 29. 6(4):e19468.
[Link]

Ontiveros E, Halwani A, Stunz L, Janz S, Bishop G.  A new mouse model of cooperation between MYC and LMP1 in B cell lymphoma development.  Keystone Symposium on Normal and Abnormal B Cells, Whistler, Alberta, Canada.  2011 April. 

Arcipowski K, Bishop G.  The roles of TRAF6 and TAK1 in LMP1-mediated B cell functions.  Keystone Symposium on Normal and Abnormal B Cells, Whistler, Alberta, Canada.  2011 April. 

Arcipowski K, Stunz L, Graham J, Kraus Z, Vanden Bush T, Bishop G.  Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1).  J Biol Chem.  2011 March 25. 286(12):9948-55.
[Link]

Decker D, Hostager B, Bishop G.  CD40 signaling.  Spring Press.  2011. 

Xie P, Kraus Z, Stunz L, Liu Y, Bishop G.  TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling.  J Immunol.  2011 January 1. 186(1):143-55.
[Link]

Peters A, Bishop G.  Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling.  J Immunol.  2010 December 1. 185(11):6555-62.
[Link]

Hildebrand J, Luo Z, Manske M, Price-Troska T, Ziesmer S, Lin W, Hostager B, Slager S, Witzig T, Ansell S, Cerhan J, Bishop G, Novak A.  A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.  J Exp Med.  2010 November 22. 207(12):2569-79.
[Link]

Munroe M, Cherascu B, Field E, James J, Bishop G.  Inhibition of inflammation in PBMCs from RA patients by the GABA-A ligand Honokiol.  Autumn Immunology Conference, Chicago, IL.  2010 November. 

Arcipowski K, Stunz L, Graham J, Kraus Z, Vanden Bush T, Bishop G.  Molecular mechanisms of TRAF6 utilization by the oncogenic viral mimic of CD40, LMP1.  6th Biennial All-Iowa Virology Symposium.  2010 November. 

Arcipowski K, Stunz L, Graham J, Kraus Z, Vanden Bush T, Bishop G.  Molecular mechanisms of TRAF6 utilization by the oncogenic viral mimic of CD40, LMP1.  Autumn Immunology Conference, Chicago, IL.  2010 November. 

Vanden Bush T, Bishop G.  Regulation of cytokine production by CDK4 in antigen presenting cells.  Autumn Immunology Conference, Chicago, IL.  2010 November. 

Buchta C, Stunz L, Vanden Bush T, Bishop G.  Role of TRAF5 in TLR signaling.  Autumn Immunology Conference, Chicago, IL.  2010 November. 

Lin W, Bishop G.  TRAF3 and TRAF6 interaction in the cytoplasm of resting or activated B cells.  Autumn Immunology Conference, Chicago, IL.  2010 November. 

Munroe M, Businga T, Kline J, Bishop G.  Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma.  J Immunol.  2010 November 1. 185(9):5586-97.
[Link]

Peters A, Stunz L, Meyerholz D, Mohan C, Bishop G.  Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice.  J Immunol.  2010 October 1. 185(7):4053-62.
[Link]

Graham J, Arcipowski K, Bishop G.  Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1.  Immunol Rev.  2010 September. 237(1):226-48.
[Link]

Decker D, Bishop G.  Characterization of the role of indirect TRAF6 association in CD40 signaling.  American Association of Immunologists, Baltimore, MD.  2010 May. 

Tseng W, Lu J, Bishop G, Watson A, Sage A, Demer L, Tintut Y.  Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids.  J Lipid Res.  2010 May. 51(5):1010-6.
[Link]

Graham J, Bishop G.  Role of receptor-mediated TRAF degradation in lymphocyte activation.  American Association of Immunologists, Baltimore, MD.  2010 May. 

Hildebrand J, Bishop G.  TRAF6, a new member of the proximal signaling complex recruited by BAFFR and TACI in B lymphocytes.  American Association of Immunologists, Baltimore, MD.  2010 May. 

Hildebrand J, Xie P, Bishop G.  Chapter 5. Signal transduction by receptors for BAFF and APRIL.  Humana Press, NJ.  2010. 

Munroe M, Bishop G.  Abrogation of established inflammatory arthritis by the GABA-A agonist Honokiol.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Decker D, Bishop G.  Characterization of the role of indirect TRAF6 association in CD40 signaling.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Arcipowski K, Stunz L, Bishop G.  Molecular mechanisms of TRAF6 utilization by the oncogenic viral mimic of CD40, LMP1.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Buchta C, Vanden Bush T, Bishop G.  Optimizing the source of APC in cellular vaccines.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Peters A, Bishop G.  Role of TRAF3 in enhanced signaling by a polymorphism of human CD40, hCD40P227A.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Graham J, Bishop G.  The role of TRAF degradation in CD40 versus LMP1 signaling.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Hildebrand J, Bishop G.  TRAF6, a new member of the proximal signaling complex recruited by BAFFR and TACI in B lymphocytes.  Autumn Immunology Conference, Chicago, IL.  2009 November. 

Vanden Bush T, Buchta C, Claudio J, Bishop G.  Cutting Edge: Importance of IL-6 and cooperation between innate and adaptive immune receptors in cellular vaccination with B lymphocytes.  J Immunol.  2009 October 15. 183(8):4833-7.
[Link]

Kraus Z, Nakano H, Bishop G.  TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40.  Proc Natl Acad Sci U S A.  2009 October 6. 106(40):17140-5.
[Link]

Peters A, Stunz L, Bishop G.  CD40 and autoimmunity: the dark side of a great activator.  Semin Immunol.  2009 October. 21(5):293-300.
[Link]

Poovassery J, Vanden Bush T, Bishop G.  Antigen receptor signals rescue B cells from TLR tolerance.  J Immunol.  2009 September 1. 183(5):2974-83.
[Link]

Graham J, Moore C, Bishop G.  Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1.  J Immunol.  2009 September 1. 183(5):2966-73.
[Link]

Munroe M, Bishop G.  Abrogation of established inflammatory arthritis by the GABA-A agonist Honokiol.  American Association of Immunologists, Seattle, WA.  2009 May. 

Stunz L, Bishop G.  Interactions between LMP1 and CD40 signals.  American Association of Immunologists, Seattle, WA.  2009 May. 

Graham J, Moore C, Bishop G.  The role of the TRAF2/3 binding site in LMP1 and CD40 signaling.  American Association of Immunologists, Seattle, WA.  2009 May. 

Poovassery J, VandenBush T, Bishop G.  TLR7 tolerance in B cells: prevention and rescue by antigen receptor signals.  American Association of Immunologists, Seattle, WA.  2009 March. 

Bishop G, Hostager B.  Assembly of signaling complexes for TNF receptor family molecules, Chapter 50.  Academic Press, Inc..  2009. 

Kraus Z, Haring J, Bishop G.  TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection.  J Immunol.  2008 December 1. 181(11):7800-9.
[Link]

Poovassery J, VandenBush T, Bishop G.  Antigen receptor signals rescue B cells from TLR tolerance.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Peters A, Bishop G.  LMP1 accelerates autoimmunity in B6.Sle1 mice.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Hildebrand J, Mayne C, Hayes C, Bishop G.  Mature B cell deficiency in the A/WySnJ mouse is associated with altered TRAF interactions with BAFFR.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Arcipowski K, Stunz L, Hostager B, Bishop G.  Molecular mechanisms of TRAF6 activation by CD40 and its oncogenic viral mimic, LMP1.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

VandenBush T, Bishop G.  Optimizing B lymphocyte stimulation for use as cellular vaccines.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Munroe M, Bishop G.  Potential anti-inflammatory role for E. Angustifolia in a mouse model of inflammatory arthritis.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Graham J, Bishop G.  The TRAF2/3 binding site in LMP1 and CD40 signaling.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Kraus Z, Bishop G.  TRAF5 is a positive regulator of LMP1 signaling in vivo.  Autumn Immunology Conference, Chicago, IL.  2008 November. 

Peters A, Plenge R, Graham R, Altshuler D, Moser K, Gaffney P, Bishop G.  A novel polymorphism of the human CD40 receptor with enhanced function.  Blood.  2008 September 1. 112(5):1863-71.
[Link]

Xie P, Kraus Z, Stunz L, Bishop G.  Roles of TRAF molecules in B lymphocyte function.  Cytokine Growth Factor Rev.  2008 July. 19(3-4):199-207.
[Link]

Xue H, Jing X, Bollenbacher-Reilley J, Zhao D, Haring J, Yang B, Liu C, Bishop G, Harty J, Leonard W.  Targeting the GA binding protein beta1L isoform does not perturb lymphocyte development and function.  Mol Cell Biol.  2008 July. 28(13):4300-9.
[Link]

Peters A, Gaffney P, Bishop G.  A novel polymorphism in human CD40 enhances B cell activation.  American Association of Immunologists, San Diego, CA.  2008 April. 

Kraus Z, Haring J, Harty J, Bishop G.  Defects in CD8+ T cell expansion, memory, and response to infection in mice lacking TRAF5.  American Association of Immunologists, San Diego, CA.  2008 April. 

Hildebrand J, Larison K, Maynes C, Hayes C, Bishop G.  Mature B cell deficiency in the A/WySnJ mouse is associated with altered BAFFR-TRAF interactions.  American Association of Immunologists, San Diego, CA.  2008 April. 

Xie P, Brown L, Stunz L, Bishop G.  TRAF3 inhibits signaling by TLRs in B lymphocytes.  American Association of Immunologists, San Diego, CA.  2008 April. 

Vanden Bush T, Bishop G.  TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation.  Eur J Immunol.  2008 February. 38(2):400-9.
[Link]

Bishop G.  Target Assessment for TRAF2.  Targeted Proteins Data Base.  2008. 

Xie P, Bishop G.  Target Assessment for TRAF3.  Targeted Proteins Data Base.  2008. 

Kraus Z, Bishop G.  Target Assessment for TRAF5.  Targeted Proteins Data Base.  2008. 

Peters A, Gaffney P, Bishop G.  A novel polymorphism in human CD40 enhances B cell activation.  Autumn Immunology Conference, Chicago, IL.  2007 November. 

Munroe M, Businga T, Kline J, Bishop G.  Effects of the anti-inflammatory, natural plant product Honokiol, in a mouse model of asthma.  Autumn Immunology Conference, Chicago, IL.  2007 November. 

VandenBush T, Bishop G.  Molecular mechanisms of synergy between CD40 and TLR7.  Autumn Immunology Conference, Chicago, IL.  2007 November. 

Graham J, Moore C, Bishop G.  Role of the nature of the TRAF binding site in signaling differences between CD40 and its oncogenic viral mimic, LMP1.  Autumn Immunology Conference, Chicago, IL.  2007 November. 

Hildebrand J, Larison K, Mayne C, Hayes C, Bishop G.  TRAF interactions with the BAFF receptor of the mutant A/WySnJ mouse.  Autumn Immunology Conference, Chicago, IL.  2007 November. 

Kraus Z, Haring J, Harty J, Bishop G.  TRAF5 requirement for CD8+ T cell responses to an intracellular pathogen.  Autumn Immunology Conference, Chicago, IL.  2007 November. 

Rahhal R, Vanden Bush T, McLendon M, Apicella M, Bishop G.  Differential effects of Francisella tularensis lipopolysaccharide on B lymphocytes.  J Leukoc Biol.  2007 October. 82(4):813-20.
[Link]

Rowland S, Tremblay M, Ellison J, Stunz L, Bishop G, Hostager B.  A novel mechanism for TNFR-associated factor 6-dependent CD40 signaling.  J Immunol.  2007 October 1. 179(7):4645-53.
[Link]

Xie P, Stunz L, Larison K, Yang B, Bishop G.  Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs.  Immunity.  2007 August. 27(2):253-67.
[Link]

Munroe M, Arbiser J, Bishop G.  Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis.  J Immunol.  2007 July 15. 179(2):753-63.
[Link]

Xie P, Stunz L, Larison K, Yang B, Bishop G.  A role for TRAF3 in B cell homeostasis.  American Association of Immunologists, Miami, FL.  2007 May. 

Peters A, Gaffney P, Bishop G.  A polymorphism in human CD40 correlates with autoimmunity and enhances B cell activation.  American Academy of Allergy, Asthma, & Immunology Annual Meeting, San Diego, CA.  2007 February. 

Munroe M, Bishop G.  A costimulatory function for T cell CD40.  J Immunol.  2007 January 15. 178(2):671-82.
[Link]

Bishop G.  Immunology at the University of Iowa.  Immunol Res.  2007. 39(1-3):1-3.
[Link]

Bishop G, Xie P.  Multiple roles of TRAF3 signaling in lymphocyte function.  Immunol Res.  2007. 39(1-3):22-32.
[Link]

Bishop G, Moore C, Xie P, Stunz L, Kraus Z.  TRAF proteins in CD40 signaling.  Adv Exp Med Biol.  2007. 597:131-51.
[Link]

Bishop G, Moore C, Xie P, Stunz L, Kraus Z.  TRAF proteins in CD40 signaling.  Landes Bioscience, TX.  2007. 

Peters A, Gaffney P, Bishop G.  A polymorphism in human CD40 correlates with autoimmunity and enhances B cell activation.  Autumn Immunology Conference, Chicago, IL.  2006 November. 

Kraus Z, Haring J, Harty J, Bishop G.  A role for TRAF5 in CD8+ T cell responses.  Autumn Immunology Conference, Chicago, IL.  2006 November. 

Munroe M, Bishop G.  Abrogation of inflammation by honokiol: GABA(A)-mediated alteration of CD40 and LMP1 signaling in B cells.  Autumn Immunology Conference, Chicago, IL.  2006 November. 

VandenBush A, Bishop G.  Cooperation between TLRs and CD40: Synergy in human and mouse B cell IL-6 production via regulation of c-Jun N-terminal kinase (JNK) and the phosphatase PP2A.  Autumn Immunology Conference, Chicago, IL.  2006 November. 

Rahhal R, VandenBush A, McLendon M, Apicella M, Bishop G.  Differential effects of virulent F. tularensis LPS on human peripheral B lymphocytes.  Society for Leukocyte Biology, San Antonio, TX.  2006 November. 

Benson R, Hostager B, Bishop G.  Rapid CD40-mediated rescue from CD95-induced apoptosis requires TNFR-associated factor-6 and PI3K.  Eur J Immunol.  2006 September. 36(9):2535-43.
[Link]

Xie P, Stunz L, Larison K, Yang B, Bishop G.  B cell-specific TRAF3-deficient mice exhibit expanded B cell compartments in secondary lymphoid organs.  American Association of Immunologists, Boston, MA.  2006 May. 

Stunz L, Bishop G.  Mechanisms of B cell autoimmunity in LMP1 transgenic mice.  American Association of Immunologists, Boston, MA.  2006 May. 

Xie P, Hostager B, Munroe M, Moore C, Bishop G.  Cooperation between TNF receptor-associated factors 1 and 2 in CD40 signaling.  J Immunol.  2006 May 1. 176(9):5388-400.
[Link]

Moore C, Bishop G.  Molecular mechanisms regulating TRAF degradation mediated by members of the TNFR superfamily.  Keystone Meeting on B Lymphocytes, Keystone, CO.  2006 February. 

Kraus Z, Bishop G.  Roles played by members of the TRAF family of adapter proteins in signaling by CD40 and CD27.  Keystone Meeting on B Lymphocytes, Keystone, CO.  2006 February. 

Bishop G, Hostager B.  CD40 Molecule Page, AfCS Signaling Gateway.  Nature Onlin.  2006. 

Munroe M, Bishop G.  Anti-inflammatory effects of honokiol on CD40 and LMP1-mediated signaling.  Autumn Immunology Conference, Chicago, IL.  2005 November. 

VandenBush A, Bishop G.  Cooperation between CD40 and TLR signaling in B cells.  Autumn Immunology Conference, Chicago, IL.  2005 November. 

Kraus Z, Bishop G.  Function of TRAF molecules in the signal transduction of CD27 in B lymphocytes.  Autumn Immunology Conference, Chicago, IL.  2005 November. 

Benson R, Hostager B, Bishop G.  Rapid CD40 and TLR9 rescue from CD95 apoptosis.  Autumn Immunology Conference, Chicago, IL.  2005 November. 

Moore C, Bishop G.  Role of TRAFs in CD40-mediated isotype switching.  Autumn Immunology Conference, Chicago, IL.  2005 November. 

Andrade R, Wessendarp M, Portillo J, Yang J, Gomez F, Durbin J, Bishop G, Subauste C.  TNF receptor-associated factor 6-dependent CD40 signaling primes macrophages to acquire antimicrobial activity in response to TNF-alpha.  J Immunol.  2005 November 1. 175(9):6014-21.
[Link]

Wu S, Xie P, Welsh K, Li C, Ni C, Zhu X, Reed J, Satterthwait A, Bishop G, Ely K.  LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3.  J Biol Chem.  2005 September 30. 280(39):33620-6.
[Link]

Moore C, Bishop G.  Differential regulation of CD40-mediated TNF receptor-associated factor degradation in B lymphocytes.  J Immunol.  2005 September 15. 175(6):3780-9.
[Link]

Xie P, Bishop G.  Exploration of signaling by TNFR superfamily members in B cells deficient in multiple TRAFs.  American Association of Immunologists, San Diego, CA.  2005 April. 

Stunz L, Bishop G.  In vivo interactions between CD40 and LMP1.  American Association of Immunologists, San Diego, CA.  2005 April. 

Mukundan L, Bishop G, Head K, Zhang L, Wahl L, Suttles J.  TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages.  J Immunol.  2005 January 15. 174(2):1081-90.
[Link]

Bishop G.  CD40 and its viral mimic LMP1.  Modern Aspects of Immunobiology.  2005. 16:6.

Munroe M, Bishop G.  Role of tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) in distinct and overlapping CD40 and TNF receptor 2/CD120b-mediated B lymphocyte activation.  J Biol Chem.  2004 December 17. 279(51):53222-31.
[Link]

Kraus Z, Bishop G.  A mutant TRAF2 lacking the C-terminal domain forms spontaneous aggregates in TRAF2-deficient B cells.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

Benson R, Hostager B, Bishop G.  CD40 rescue from CD95 apoptosis requires TRAF6 and PI3-kinase.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

Stunz L, Bishop G.  Effects of co-expression of CD40 and LMP1 in vivo.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

VandenBush A, Bishop G.  Interactions between innate and adaptive immune receptors in B cells.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

Moore C, Bishop G.  Receptor-induced TRAF degradation in B lymphocytes.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

Xie P, Bishop G.  Roles of TRAF3 in signaling to B lymphocytes by CTAR1 and 2 of the EBV-encoded oncoprotein LMP1.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

Munroe M, Bishop G.  Signaling to T lymphocytes by CD40.  Autumn Immunology Conference, Chicago, IL.  2004 November. 

Xie P, Bishop G.  Roles of TNF receptor-associated factor 3 in signaling to B lymphocytes by carboxyl-terminal activating regions 1 and 2 of the EBV-encoded oncoprotein latent membrane protein 1.  J Immunol.  2004 November 1. 173(9):5546-55.
[Link]

Bishop G.  The multifaceted roles of TRAFs in the regulation of B-cell function.  Nat Rev Immunol.  2004 October. 4(10):775-86.
[Link]

Stunz L, Busch L, Munroe M, Sigmund C, Tygrett L, Waldschmidt T, Bishop G.  Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture.  Immunity.  2004 August. 21(2):255-66.
[Link]

Munroe M, Bishop G.  CD40 and TNFR2 activate NF-kB in distinct, TRAF2-dependent ways.  International Congress of Immunology, Montreal, Canada.  2004 July. 

Oxley K, Bishop G.  Membrane recruitment of TNFR family members in normal and malignant prostate cells.  Conference on Genitourinary Malignancies, Iowa City, IA.  2004 June. 

Munroe M, Bishop G.  A comparison of signaling mechanisms of CD40 and TNFR2 in B lymphocytes: Distinct and overlapping pathways.  American Association of Immunologists, Washington, DC.  2004 April. 

Benson R, Bishop G.  PI3-kinase is required for CD40-mediated protection of B cells from CD95-mediated apoptosis.  American Association of Immunologists, Washington, DC.  2004 April. 

Moore C, Bishop G.  Receptor-induced TRAF degradation in B lymphocytes.  American Association of Immunologists, Washington, DC.  2004 April. 

Xie P, Hostager B, Bishop G.  Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes.  J Exp Med.  2004 March 1. 199(5):661-71.
[Link]

Barabanova Y, Kang H, Myoung J, Kang B, Bishop G, Kim B.  Role of the major histocompatibility complex class II transmembrane region in antigen presentation and intracellular trafficking.  Immunology.  2004 February. 111(2):165-72.
[Link]

Haxhinasto S, Bishop G.  Synergistic B cell activation by CD40 and the B cell antigen receptor: role of B lymphocyte antigen receptor-mediated kinase activation and tumor necrosis factor receptor-associated factor regulation.  J Biol Chem.  2004 January 23. 279(4):2575-82.
[Link]

Hostager B, Haxhinasto S, Rowland S, Bishop G.  Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling.  J Biol Chem.  2003 November 14. 278(46):45382-90.
[Link]

Oxley K, Bishop G.  A comparison of signaling by TNFR superfamily molecules in B lymphocytes versus normal and malignant prostate cells.  Autumn Immunology Conference, Chicago, IL.  2003 November. 

Moore C, Bishop G.  CD40-induced TRAF degradation depends upon both binding affinity and binding position.  Autumn Immunology Conference, Chicago, IL.  2003 November. 

Benson R, Bishop G.  Characterization of CD40-mediated rescue of B lymphocytes from CD95-mediated apoptosis.  Autumn Immunology Conference, Chicago, IL.  2003 November. 

Stunz L, Busch L, Waldschmidt T, Tygrett L, Bishop G.  Elevated IL-6 and autoantibody production in mice transgenically expressing the LMP1 cytoplasmic domain.  Autumn Immunology Conference, Chicago, IL.  2003 November. 

Larison K, Simmons J, Moore C, Bishop G.  Role of TRAF3 in signaling to B lymphocytes via receptors for BAFF.  Autumn Immunology Conference, Chicago, IL.  2003 November. 

Munroe M, Bishop G.  Signaling to B lymphocytes by CD40 and TNFR2.  Autumn Immunology Conference, Chicago, IL.  2003 November. 

Haxhinasto S, Bishop G.  A novel interaction between protein kinase D and TNF receptor-associated factor molecules regulates B cell receptor-CD40 synergy.  J Immunol.  2003 November 1. 171(9):4655-62.
[Link]

Stunz L, Busch L, Waldschmidt T, Tygrett L, Bishop G.  B cell signaling by CD-40 and its viral mimic LMP1: the LMP1 cytoplasmic tail causes an altered phenotype in transgenic mice.  American Association of Immunologists, Denver, CO.  2003 May. 

Xie P, Hostager B, Bishop G.  Contrasting negative and positive roles for TRAF3 in signaling by CD40 vs. its oncogenic mimic LMP1.  American Association of Immunologists, Denver, CO.  2003 May. 

Moore C, Bishop G.  Receptor-induced TRAF degradation in B lymphocyte signal regulation.  American Association of Immunologists, Denver, CO.  2003 May. 

Baccam M, Woo S, Vinson C, Bishop G.  CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kappa B, AP-1, and C/EBP.  J Immunol.  2003 March 15. 170(6):3099-108.
[Link]

Bishop G, Haxhinasto S, Stunz L, Hostager B.  Antigen-specific B-lymphocyte activation.  Crit Rev Immunol.  2003. 23(3):149-97.
[Link]

Bishop G, Hostager B.  The CD40-CD154 interaction in B cell-T cell liaisons.  Cytokine Growth Factor Rev.  2003. 14(3-4):297-309.
[Link]

Bishop G, Hostager B.  TNF-R Family Signaling Complexes, Chapter 56.  Elsevier Science.  2003. 

Stunz L, Busch L, Waldschmidt T, Tygrett L, Bishop G.  B cell signaling by CD40 and its viral mimic LMP1: The LMP1 cytoplasmic tail causes an altered phenotype in transgenic mice.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Moore C, Bishop G.  Examining the regulation of TRAF degradation in B lymphocytes.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Benson R, Catlett I, Hostager B, Bishop G.  Inhibition of CD95-mediated apoptosis by B cell activation signals.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Haxhinasto S, Hostager B, Xie P, Bishop G.  Molecular mechanisms of synergy between CD40 and the BCR: Role for TRAFs 2 and 3 in receptor interaction.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Munroe M, Hostager B, Bishop G.  Role and molecular mechanisms of signaling to B lymphocytes by TNFR2.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Rowland S, Hostager B, Haxhinasto S, Bishop G.  Roles of TRAF2 in B cell signaling: Development and use of TRAF-deficient B cell lines.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Xie P, Hostager B, Bishop G.  The immune receptor CD40 and its viral mimic, the EBV-encoded oncoprotein LMP1, exhibit differential dependence on TRAF3 for signaling.  Autumn Immunology Conference, Chicago, IL.  2002 November. 

Bishop G.  Molecular characterization of signaling differences between CD40 and LMP1.  TNF Superfamily Conference, San Diego, CA.  2002 October. 

Haxhinasto S, Hostager B, Xie P, Bishop G.  Molecular mechanisms of synergy between CD40 and the BCR: Role for TRAFs 2 and 3 in receptor interaction.  TNF Superfamily Conference, San Diego, CA.  2002 October. 

Hostager B, Rowland S, Bishop G.  Roles of TRAF2 in B cell signaling: Development and use of TRAF-deficient B cell lines.  TNF Superfamily Conference, San Diego, CA.  2002 October. 

Haxhinasto S, Hostager B, Bishop G.  Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction.  J Immunol.  2002 August 1. 169(3):1145-9.
[Link]

Bishop G, Hostager B, Brown K.  Mechanisms of TNF receptor-associated factor (TRAF) regulation in B lymphocytes.  J Leukoc Biol.  2002 July. 72(1):19-23.
[Link]

Bishop G, Busch L.  Molecular mechanisms of B-lymphocyte transformation by Epstein-Barr virus.  Microbes Infect.  2002 July. 4(8):853-7.
[Link]

Brown K, Hostager B, Bishop G.  Regulation of TRAF2 signaling by self-induced degradation.  J Biol Chem.  2002 May 31. 277(22):19433-8.
[Link]

Hostager B, Bishop G.  Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b.  J Immunol.  2002 April 1. 168(7):3318-22.
[Link]

Zhu N, Ramirez L, Lee R, Magnuson N, Bishop G, Gold M.  CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway.  J Immunol.  2002 January 15. 168(2):744-54.
[Link]

Busch L, Bishop G.  Multiple carboxyl-terminal regions of the EBV oncoprotein, latent membrane protein 1, cooperatively regulate signaling to B lymphocytes via TNF receptor-associated factor (TRAF)-dependent and TRAF-independent mechanisms.  J Immunol.  2001 November 15. 167(10):5805-13.
[Link]

Bishop G.  Mechanisms of TRAF regulation in B lymphocyte signaling by CD40 and LMP1.  Cytokine Odyssey, Maui, HI.  2001 November. 

Moore C, Brown K, Bishop G.  Regulation of CD40-mediated TRAF degradation in B cells.  Autumn Immunology Conference, Chicago, IL.  2001 November. 

Haxhinasto S, Bishop G.  Roles of threonine 234 and PKCμ in cooperation between BCR and CD40-mediated signaling.  Autumn Immunology Conference, Chicago, IL.  2001 November. 

Xie P, Hostager B, Bishop G.  Use of TraF3-/- B cell lines to study the roles of TRAF3 in signaling by CD40 and LMP1.  Autumn Immunology Conference, Chicago, IL.  2001 November. 

Bishop G, Hostager B.  B lymphocyte activation by contact-mediated interactions with T lymphocytes.  Curr Opin Immunol.  2001 June. 13(3):278-85.
[Link]

Catlett I, Xie P, Hostager B, Bishop G.  Signaling through MHC class II molecules blocks CD95-induced apoptosis.  J Immunol.  2001 May 15. 166(10):6019-24.
[Link]

Brown K, Hostager B, Bishop G.  Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).  J Exp Med.  2001 April 16. 193(8):943-54.
[Link]

Zhu M, Ramirez L, Lee R, Pelech S, Bishop G, Gold M.  CD40 signaling in B cells regulates the expression of pim-1 via the NF-κB pathway.  American Association of Immunologists, Orlando, FL.  2001 April. 

Hostager B, Bishop G.  Modulation of CD40-mediated B cell activation by TNFR2 through TRAF2.  American Association of Immunologists, Orlando, FL.  2001 April. 

Busch L, Bishop G.  Structure-function analysis of signaling to B cells by the oncogenic protein, LMP1.  Keystone Conference on B Lymphocytes.  2001 April. 

Bishop G, Ramirez L, Baccam M, Busch L, Pederson L, Tomai M.  The immune response modifier resiquimod mimics CD40-induced B cell activation.  Cell Immunol.  2001 February 25. 208(1):9-17.
[Link]

Bishop G, Hostager B.  Molecular mechanisms of CD40 signaling.  Arch Immunol Ther Exp (Warsz).  2001. 49(2):129-37.
[Link]

Bishop G, Hostager B.  Signaling by CD40 and its mimics in B cell activation.  Immunol Res.  2001. 24(2):97-109.
[Link]

Bishop G, Hsing Y, Hostager B, Jalukar S, Ramirez L, Tomai M.  Molecular mechanisms of B lymphocyte activation by the immune response modifier R-848.  J Immunol.  2000 November 15. 165(10):5552-7.
[Link]

Edelheit R, Hostager B, Ramirez L, Bishop G.  Characterization of CD40 signals required for induction of IgE.  Autumn Immunology Conference, Chicago, IL.  2000 November. 

Brown K, Hostager B, Bishop G.  Differential signaling and TRAF degradation mediated by CD40 and the EBV oncoprotein LMP1.  Autumn Immunology Conference, Chicago, IL.  2000 November. 

Haxhinasto S, Bishop G.  Molecular mechanisms of interaction between the BCR and CD40.  Autumn Immunology Conference, Chicago, IL.  2000 November. 

Busch L, Bishop G.  Structure-function analysis of the LMP1 carboxyl terminus.  Autumn Immunology Conference, Chicago, IL.  2000 November. 

Hostager B, Catlett I, Bishop G.  Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling.  J Biol Chem.  2000 May 19. 275(20):15392-8.
[Link]

Brown K, Hostager B, Bishop G.  Differential signaling and TRAF degradation mediated by CD40 and the EBV oncoprotein LMP1.  American Association of Immunologists, Seattle, WA.  2000 May. 

Bishop G, Hostager B, Brown K.  TRAFs and rafts in signaling by CD40 and LMP1.  8th International Congress on TNF and Related Molecules, Trondheim, Norway.  2000 May. 

Hostager B, Bishop G.  TRAF rafting in CD40 signaling.  8th International Congress on TNF and Related Molecules, Trondheim, Norway.  2000 March. 

Jalukar S, Hostager B, Bishop G.  Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functions.  J Immunol.  2000 January 15. 164(2):623-30.
[Link]

Baccam M, Bishop G.  Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells.  Eur J Immunol.  1999 December. 29(12):3855-66.
[Link]

Catlett I, Bishop G.  B cell receptor-mediated rescue of B cells from Fas-induced apoptosis.  Autumn Immunology Conference, Chicago, IL.  1999 November. 

Brown K, Bishop G.  Contrasting signaling by the EBV oncogenic protein LMP1 and CD40: Implications for B cell activation.  Autumn Immunology Conference, Chicago, IL.  1999 November. 

Baccam M, Bishop G.  Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells.  Autumn Immunology Conference, Chicago, IL.  1999 November. 

Hostager B, Catlett I, Bishop G.  Recruitment of CD40, TRAF2, and TRAF3 to membrane microdomains during CD40 signaling.  Autumn Immunology Conference, Chicago, IL.  1999 November. 

Busch L, Bishop G.  Structure-function analysis of the LMP1 carboxyl terminus.  Autumn Immunology Conference, Chicago, IL.  1999 November. 

Catlett I, Bishop G.  Cutting edge: a novel mechanism for rescue of B cells from CD95/Fas-mediated apoptosis.  J Immunol.  1999 September 1. 163(5):2378-81.
[Link]

Hostager B, Bishop G.  Cutting edge: contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation.  J Immunol.  1999 June 1. 162(11):6307-11.
[Link]

Hostager B, Bishop G.  Contrasting roles of TRAFs 2 and 3 in CD40-stimulated antibody secretion.  AAI Annual Meeting, Washington, DC.  1999 April. 

Hsing Y, Bishop G.  Distinct subsets of CD40-mediated B cell effector functions require NF-κB activation.  AAI Annual Meeting, Washington, DC.  1999 April. 

Catlett I, Bishop G.  Early rescue of B cells from Fas-induced apoptosis.  AAI Annual Meeting, Washington, DC.  1999 April. 

Baccam M, Bishop G.  NF-κB activation is not sufficient, and binding of TRAFs 2 and 3 is not required for CD40-mediated IL-6 production in B cells.  AAI Annual Meeting, Washington, DC.  1999 April. 

Jalukar S, Hostager B, Bishop G.  Role of TRAF6 in CD40-mediated B cell activation.  AAI Annual Meeting, Washington, DC.  1999 April. 

Hsing Y, Bishop G.  Requirement for nuclear factor-kappaB activation by a distinct subset of CD40-mediated effector functions in B lymphocytes.  J Immunol.  1999 March 1. 162(5):2804-11.
[Link]

Busch L, Bishop G.  The EBV transforming protein, latent membrane protein 1, mimics and cooperates with CD40 signaling in B lymphocytes.  J Immunol.  1999 March 1. 162(5):2555-61.
[Link]

Brown K, Bishop G.  Comparison of the cytoplasmic domains of CD40 and the EBV transforming protein LMP1 in B cell signaling.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Hostager B, Bishop G.  How CD40-mediated antibody secretion is regulated by TRAF's 2 and 3.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Busch L, Bishop G.  LMP1 mimics and enhances CD40 signaling.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Hsing Y, Bishop G.  NF-κB activation is required for a distinct subset of CD40-mediated B cell functions.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Baccam M, Bishop G.  Regulation of IL-6 production in B cells by CD40-mediated signaling.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Jalukar S, Hostager B, Bishop G.  Role of TRAF6 in CD40 signaling to B lymphocytes.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Catlett I, Bishop G.  The B cell antigen receptor blocks Fas-mediated apoptosis by preventing caspase activation.  Autumn Immunology Conference, Chicago, IL.  1998 November. 

Hsing Y, Bishop G.  Characterization of NF-κB-dependent and independent signaling functions of CD40 in B lymphocytes.  American Association of Immunologists, San Francisco, CA.  1998 April. 

Bishop G.  MHC Class II.  Academic Press, London.  1998. 

Catlett I, Bishop G.  Crosstalk between Fas, CD40, Class II MHC, and the BCR.  Midwinter Conference of Immunologists, Pacific Grove, CA.  1998 January. 

Hostager B, Bishop G.  Role of TRAF3 in CD40 signaling.  Midwinter Conference of Immunologists, Pacific Grove, CA.  1998 January. 

Hsing Y, Hostager B, Bishop G.  Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes.  J Immunol.  1997 November 15. 159(10):4898-906.
[Link]

Hsing Y, Hostager B, Bishop G.  Characterization of CD40 signaling events regulating NF-κB in B cells.  Autumn Immunology Conference, Chicago, IL.  1997 November. 

Hostager B, Bishop G.  Examining the role of TRAF3 in CD40 signaling.  Autumn Immunology Conference, Chicago, IL.  1997 November. 

Catlett I, Bishop G.  Interactions between Fas, MHC class II and CD40 signaling pathways.  Autumn Immunology Conference, Chicago, IL.  1997 November. 

Baccam M, Hostager B, Bishop G.  Mechanisms involved in the interactions between the CD40 and BCR-mediated signaling pathways.  Autumn Immunology Conference, Chicago, IL.  1997 November. 

Busch L, Bishop G.  The EBV transforming protein, LMP1 mimics CD40 signalingn.  Autumn Immunology Conference, Chicago, IL.  1997 November. 

Rokhlin O, Hostager B, Bishop G, Sidorenko S, Glover R, Gudkov A, Cohen M.  Dominant nature of the resistance to Fas- and tumor necrosis factor-alpha-mediated apoptosis in human prostatic carcinoma cell lines.  Cancer Res.  1997 September 15. 57(18):3941-3.
[Link]

Rokhlin O, Bishop G, Hostager B, Waldschmidt T, Sidorenko S, Pavloff N, Kiefer M, Umansky S, Glover R, Cohen M.  Fas-mediated apoptosis in human prostatic carcinoma cell lines.  Cancer Res.  1997 May 1. 57(9):1758-68.
[Link]

Hsing Y, Hostager B, Bishop G.  Molecular characterization of CD40 cytoplasmic signaling determinants regulating NF-κB activation in B cells.  American Association of Immunologists, San Francisco, CA.  1997 February. 

Hostager B, Baccam M, Bishop G.  Structural features of CD40 involved in delivery of proximal and distal signals.  Midwinter Conference of Immunologists, Pacific Grove, CA.  1997 January. 

Olson J, Bishop G, Grose C.  Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms.  J Virol.  1997 January. 71(1):110-9.
[Link]

Hsing Y, Hostager B, Bishop G.  CD40 structural and molecular requirements for activation of NF-κB.  Autumn Immunology Conference, Chicago, IL.  1996 November. 

Baccam M, Hostager B, Bishop G.  Enhancement of CD40 signaling by the B cell antigen receptor.  Autumn Immunology Conference, Chicago, IL.  1996 November. 

Hostager B, Baccam M, Bishop G.  Structural features of CD40 involved in delivery of proximal and distal signals.  Autumn Immunology Conference, Chicago, IL.  1996 November. 

Olson J, Bishop G, Grose C.  VZV FcR contains a YXXL motif important for tyrosine phosphorylation and endocytosis.  Autumn Immunology Conference, Chicago, IL.  1996 November. 

Li Y, Baccam M, Waters S, Pessin J, Bishop G, Koretzky G.  CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.  J Immunol.  1996 August 15. 157(4):1440-7.
[Link]

Hostager B, Hsing Y, Harms D, Bishop G.  Different CD40-mediated signaling events require distinct CD40 structural features.  J Immunol.  1996 August 1. 157(3):1047-53.
[Link]

Bishop G, Hostager B, Hsing Y, Harms D.  Distinct CD40 structural requirements regulate CD40-mediated signals.  American Association of Immunologists, New Orleans, LA.  1996 June. 

Rokhlin O, Bishop G, Hostager B, Sidorenko S, Cohen M.  Expression of Fas and CD40 in human prostatic carcinoma cell lines.  American Association of Immunologists, New Orleans, LA.  1996 June. 

Harton J, Huff K, Embers M, Catlett I, Baccam M, Bishop G.  Analysis of the roles of protein tyrosine kinases and cAMP-dependent kinase in class II-mediated B cell signaling.  Autumn Immunology Conference, Chicago, IL.  1995 November. 

Baccam M, Hostager B, Harton J, Bishop G.  Role of the cytoplasmic domain of CD40 in membrane Ig-mediated enhancement of CD40 signaling.  Autumn Immunology Conference, Chicago, IL.  1995 November. 

Hostager B, Baccam M, Harton J, Bishop G.  Structure-function analysis of the cytoplasmic domain of CD40.  Autumn Immunology Conference, Chicago, IL.  1995 November. 

Lambert L, Berling J, Thompson S, Harton J, Bishop G, Choi E.  Polymorphism in the beta chain of IAq versus IAp influences presentation of protein but not peptide antigens.  Cell Immunol.  1995 October 15. 165(2):202-10.
[Link]

Louie S, Ramirez L, Harton J, Bishop G.  Positive and negative regulation of Thy-1 expression on B lymphocytes by IL-4.  Int Immunol.  1995 September. 7(9):1497-503.
[Link]

Harton J, Van Hagen A, Bishop G.  The cytoplasmic and transmembrane domains of MHC class II beta chains deliver distinct signals required for MHC class II-mediated B cell activation.  Immunity.  1995 September. 3(3):349-58.
[Link]

Baccam M, Harms D, Hostager B, Harton J, Bishop G.  Characterization of CD40 signaling in B and T cell lines.  9th International Congress of Immunology, San Francisco, CA.  1995 July. 

Harton J, Van Hagen A, Bishop G.  The cytoplasmic and transmembrane domains of MHC class II β chains deliver distinct signals required for class II-mediated B cell activation.  9th International Congress of Immunology, San Francisco, CA.  1995 July. 

Bishop G, Warren W, Berton M.  Signaling via major histocompatibility complex class II molecules and antigen receptors enhances the B cell response to gp39/CD40 ligand.  Eur J Immunol.  1995 May. 25(5):1230-8.
[Link]

Krieg A, Yi A, Matson S, Waldschmidt T, Bishop G, Teasdale R, Koretzky G, Klinman D.  CpG motifs in bacterial DNA trigger direct B-cell activation.  Nature.  1995 April 6. 374(6522):546-9.
[Link]

Krieg A, Yi A, Waldschmidt T, Bishop G.  Immune stimulation by a CpG motif: mechanisms and potential applications.  2nd International Conference on Antisense Nucleic Acids, Garmisch-Partenkirchen, Germany.  1995 February. 

Weiner G, Belani R, Woolridge J, Bishop G, Koretzky G.  Anti-idiotype antibody induces activation signals and upregulates B7-2 expression on a murine B-cell lymphoma.  American Society for Hematology, Nashville, TN.  1994 December. 

Van Hagen A, Harton J, Bishop G.  A PCR-based technique used to generate a saturation library of point mutants in a defined region of an MHC gene.  Autumn Immunology Conference, Chicago, IL.  1994 October. 

Harton J, Bishop G.  Evidence for the role of glycine (227) and proline (228) in the cytoplasmic tail of Ab in class II-mediated B cell signaling.  Autumn Immunology Conference, Chicago, IL.  1994 October. 

Harms D, Harton J, Ramirez L, Krieg A, Bishop G.  Regulation of expression of B7-1 and B7-2 in murine B lymphocytes.  Autumn Immunology Conference, Chicago, IL.  1994 October. 

Bishop G, Ramirez L, Waldschmidt T.  Differential responses to Ig and class II-mediated signals in splenic B cell subsets from normal and autoimmune mice.  Int Immunol.  1994 July. 6(7):1049-59.
[Link]

Harton J, Bishop G.  Length and sequence requirements of the cytoplasmic domain of the A beta molecule for class II-mediated B cell signaling.  9th International H-2/HLA Workshop, Garda, Italy.  1994 May. 

Harton J, Bishop G.  Regulation of class II-mediated B cell signaling.  5th International Conference on Lymphocyte Activation, Newport Beach, CA.  1994 February. 

Harton J, Bishop G.  Length and sequence requirements of the cytoplasmic domain of the A beta molecule for class II-mediated B cell signaling.  J Immunol.  1993 November 15. 151(10):5282-9.
[Link]

Harton J, Bishop G.  An analysis of specific residues in the cytoplasmic tail of Aβ required for class II-mediated signaling.  Autumn Immunology Conference, Chicago, IL.  1993 November. 

Louie S, Bishop G.  IL-4 mediated transcriptional control of B cell Thy-1 expression.  Autumn Immunology Conference, Chicago, IL.  1993 November. 

Baccam M, Ramirez L, Koretzky G, Bishop G.  Molecular characterization of negative IgM-mediated signaling in the B cell clone, CHB3.  Autumn Immunology Conference, Chicago, IL.  1993 November. 

Bishop G, Ramirez L, Koretzky G.  Growth inhibition of a B cell clone mediated by ligation of IL-4 receptors or membrane IgM.  J Immunol.  1993 April 1. 150(7):2565-74.
[Link]

Bishop G, Waldschmidt T, Koretzky G.  The interaction of Ig and class II-mediated signaling in B cell lines and subsets of B cells from normal and autoimmune mice.  Keystone Symposium on Molecular Basis of B Cell Differentiation, Taos, NM.  1993 February. 

Louie S, Ramirez L, Krieg A, Maliszewski C, Bishop G.  Endogenous secretion of IL-4 maintains growth and Thy-1 expression of a transformed B cell clone.  J Immunol.  1993 January 15. 150(2):399-406.
[Link]

Harton J, Bishop G.  Effects of truncation of class II β chains on signal transduction to B cells.  American Association of Immunologists, Anaheim, CA.  1993. Fed Proc 52:4942.

Bishop G, Waldschmidt T, Koretzky G.  The interaction of Ig and class II MHC mediated signaling in B cell lines and subsets of B cells from normal and autoimmune mice.  J Cell Biochem.  1993. 17:252.

Harton J, Bishop G.  Effects of truncation of the MHC class II αβ molecule on class II-mediated signaling.  Autumn Immunology Conference, Chicago, IL.  1992 November. 

Parikh V, Bishop G, Liu K, Do B, Ghosh M, Kim B, Tucker P.  Differential structure-function requirements of the transmembranal domain of the B cell antigen receptor.  J Exp Med.  1992 October 1. 176(4):1025-31.
[Link]

Bishop G, Waldschmidt T.  Class II-mediated B cell subset activation.  Fogarty International Center Conference, NIH, "Antibodies in Natural Immunity and Autoimmune Diseases".  1992 September. 

Bishop G.  Signaling to a CD5+ B-cell clone through surface Ig and MHC class II molecules.  Ann N Y Acad Sci.  1992 May 4. 651:228-40.
[Link]

Bishop G, Harton J.  Effects of structural alterations of the MHC class II beta chain on class II-mediated B cell activation.  8th International H-2/HLA Workshop, Jekyl Island, GA.  1992 April. 

Bishop G, Hwang J.  Use of a cellular ELISA for the detection of cell surface antigens.  Biotechniques.  1992 March. 12(3):326-30.
[Link]

Louie S, Ramirez L, Bishop G.  IL-4 is an autocrine growth factor for a B cell clone.  Midwinter Conference of Immunologists, Asilomar, CA.  1992 January. 

Bishop G.  Requirements of class II-mediated B cell differentiation for class II cross-linking and cyclic AMP.  J Immunol.  1991 August 15. 147(4):1107-14.
[Link]

Bishop G.  Ig and class II-mediated signaling in CD5 B cells.  New York Academy of Sciences Conference, "CD5 B Cells in Development and Disease," Miami, FL.  1991 June. 

Harton J, Litaker W, Frelinger J, Bishop G.  Structure function analysis of the H-2 Abp gene.  Immunogenetics.  1991. 34(6):358-65.
[Link]

Harton J, Litaker R, Bishop G.  Structure-function analysis of H-2 I-AP molecules.  19th Annual Autumn Immunology Conference, Chicago.  1990 November. 

Bishop G, Pennell C, Travis W, Haughton G, Frelinger J.  Antibodies specific for Ig idiotype, but not isotype, can substitute for antigen to induce IgM secretion by a B cell clone.  Int Immunol.  1990. 2(4):285-90.
[Link]

Bishop G, Frelinger J.  Relationship between class II structure and B cell signaling.  Springer-Verlag, NY.  1990. 

Bishop G, Pennell C, Travis W, Haughton G, Frelinger J.  Antigen, anti-isotype, and anti-idiotype antibodies in B cell signaling.  Midwinter Conference of Immunologists, Asilomar, CA.  1990 January. 

Bishop G, Frelinger J.  Haplotype-specific differences in signaling by transfected class II molecules to a B cell clone.  18th Annual Autumn Immunology Conference.  1989 November. 

Bishop G, Frelinger J.  Differences between MHC haplotypes in B cell signaling by class II molecules.  7th International Congress of Immunologists, Berlin.  1989 August. 

Bishop G, Frelinger J.  Haplotype-specific differences in signaling by transfected class II molecules to a Ly-1+ B-cell clone.  Proc Natl Acad Sci U S A.  1989 August. 86(15):5933-7.
[Link]

Bishop G, Frelinger J.  Sequence-specific differences in signaling efficiency by class II molecules.  International Conference on Transgenic Mice and Mutants in MHC Research, Bar Harbor, ME.  1989 June. 

Bishop G, Frelinger J.  Haplotype-specific differences in signaling by class II molecules.  Midwinter Conference of Immunologists, Asilomar, CA.  1989 January. 

Jambou R, Snouwaert J, Bishop G, Stebbins J, Frelinger J, Fowlkes D.  High-level expression of a bioengineered, cysteine-free hepatocyte-stimulating factor (interleukin 6)-like protein.  Proc Natl Acad Sci U S A.  1988 December. 85(24):9426-30.
[Link]

Badley J, Bishop G, St John T, Frelinger J.  A simple, rapid method for the purification of poly A+ RNA.  Biotechniques.  1988 February. 6(2):114-6.
[Link]

Bishop G, McMillan M, Haughton G, Frelinger J.  Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of Ak genes.  Immunogenetics.  1988. 28(3):184-92.
[Link]

Bishop G, Frelinger J.  The class II molecule as a signal transmitter to the B cell.  Plenum Press, New York.  1988. 

Gorelick M, Bishop G, Haughton G, Pisetsky D.  Cyclosporine inhibition of CH series murine B-cell lymphomas.  Cell Immunol.  1987 June. 107(1):219-26.
[Link]

Bishop G, Frelinger J.  The class II molecule as a signal transmitter to the B cell.  International Symposium on H-2 Antigens: Genes, Molecules, Function, Bar Harbor, ME.  1987 June. 

Bishop G, Haughton G.  Role of the interleukin 2 receptor in differentiation of a clone of Ly-1+ B cells.  J Immunol.  1987 May 15. 138(10):3308-13.
[Link]

Bishop G, McCurry L, Schwartz S, Glorioso J.  Activation of human natural killer cells by herpes simplex virus type 1-infected cells.  Intervirology.  1987. 28(2):78-88.
[Link]

Bishop G, Frelinger J.  B cell signaling through class II MHC molecules is not chain-specific.  Midwinter Conference of Immunologists, Asilomar, CA.  1987 January. 

Bishop G, Haughton G.  Induced differentiation of a transformed clone of Ly-1+ B cells by clonal T cells and antigen.  Proc Natl Acad Sci U S A.  1986 October. 83(19):7410-4.
[Link]

Haughton G, Arnold L, Bishop G, Mercolino T.  The CH series of murine B cell lymphomas: neoplastic analogues of Ly-1+ normal B cells.  Immunol Rev.  1986 October. 93:35-51.
[Link]

Bishop G, Haughton G.  Requirements for antigen-specific, MHC-restricted differentiation of an Ly-1+ B cell clone.  6th International Congress of Immunology, Toronto, Canada.  1986 July. 

Bishop G, Arnold L, Haughton G.  Antigen-specific B cell tumors of mice.  Crit Rev Immunol.  1986. 6(2):105-21.
[Link]

Arnold L, Lutz P, Pennell C, Bishop G, Corley R, Haughton G, LoCascio N.  B cell tumors as models of B lymphocyte differentiation.  CRC Reviews.  1986. 

Bishop G, Haughton G.  Induced differentiation of a B cell clone: role of surface immunoglobulin, class II antigen and IL-2 receptor.  American Association of Immunologists, St Louis, MO.  1986. Fed Proc 45:714.

Bishop G, Haughton G.  Role of the LFA-1 molecule in B cell differentiation.  Curr Top Microbiol Immunol.  1986. 132:142-7.
[Link]

Bishop G, Haughton G.  Use of the CH lymphomas as models of murine B cell differentiation.  Immunol Res.  1986. 5(4):263-70.
[Link]

Bishop G, Haughton G.  Induced differentiation of a B cell clone by T cells and antigen.  Midwinter Conference of Immunologists, Asilomar, CA.  1986 January. 

Bishop G, Kümel G, Schwartz S, Glorioso J.  Specificity of human natural killer cells in limiting dilution culture for determinants of herpes simplex virus type 1 glycoproteins.  J Virol.  1986 January. 57(1):294-300.
[Link]

Bishop G, Kumel G, Schwartz S, Glorioso J.  Clonal specificity of human natural killer cells for determinants of HSV-1 glycoproteins.  10th International Herpesvirus Symposium, Ann Arbor, MI.  1985 August. 

Bishop G, Haughton G.  H-2 control of expression of an idiotype shared by normal B cells and a B-cell lymphoma.  Immunogenetics.  1985. 21(4):355-66.
[Link]

Bishop G, Marlin S, Schwartz S, Glorioso J.  Human natural killer cell recognition of herpes simplex virus type 1 glycoproteins: specificity analysis with the use of monoclonal antibodies and antigenic variants.  J Immunol.  1984 October. 133(4):2206-14.
[Link]

Bishop G, Marlin S, Schwartz S, Glorioso J.  Analysis of the specificity of natural killer cells for HSV-1 infected targets.  American Association of Immunologists, St Louis, MO.  1984. Fed Proc 43:1906.

Bishop G, Glorioso J, Schwartz S.  Role of interferon in human natural killer activity against target cells infected with HSV-1.  J Immunol.  1983 October. 131(4):1849-53.
[Link]

Bishop G, Glorioso J, Schwartz S.  Recognition by natural killer cells of viral glycoproteins on target cells infected with HSV-1.  Annual Meeting of the American Society for Virology.  1983 July. 

Bishop G, Glorioso J, Schwartz S.  Relationship between expression of herpes simplex virus glycoproteins and susceptibility of target cells to human natural killer activity.  J Exp Med.  1983 May 1. 157(5):1544-61.
[Link]

Bishop G, Glorioso J, Schwartz S.  Association of Herpes-specific glycoproteins with susceptibility to natural killer cells.  American Association of Immunologists.  1983. Fed Proc 42:437.

Bishop G, Schwartz S.  Enhancement of human natural killer cells by interferon requires RNA and protein synthesis.  Clin Immunol Immunopathol.  1982 December. 25(3):374-85.
[Link]

Bishop G, Schwartz S, Glorioso J.  Characteristics of human natural killer activity against target cells infected with Herpes simplex virus type 1.  6th Annual Herpesvirus Symposium, Cold Spring Harbor Laboratory, Cold Spring, NY.  1982 August. 

Bishop G, Schwartz S.  Metabolic requirements for interferon-enhanced human natural cytotoxicity.  American Association of Immunologists, New Orleans, LA.  1982. Fed Proc 41:3120.

Bishop G, Schwartz S.  Effects of 2'-deoxycoformycin and 2'-deoxyadenosine on human lymphocyte activation.  American Association of Immunologists, Atlanta, GA.  1981. Fed Proc 40:4826.

Bishop G, Dove W.  Semisyngeneic hybrid resistance to murine teratocarcinoma cells.  Immunogenetics.  1980. 10(4):383-93.
[Link]

Date Last Modified: 06/07/2014 - 21:56:23