Internal Medicine

Allyn L. Mark, MD

Portrait

Founding Co-Director, UI Obesity Research and Education Initiative
Professor of Internal Medicine  - Cardiovascular Medicine

Contact Information

Email: allyn-mark@uiowa.edu
Web: Medicine Alumni Society Profile

Education

MD, The University of Iowa

Residency, University of Pennsylvania
Residency, The University of Iowa
Fellowship, The University of Iowa

Licensure and Certifications

Iowa Medical License, Iowa Board of Medical Examiners
Certification, American Board of Internal Medicine
Certification, Subspecialty Board in Cardiovascular Disease

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Translational Biomedicine

Research Summary

Dr. Mark's research has focused on the role of the sympathetic nervous system in in physiologic and pathologic states. After a sabbatical in Uppsala, Sweden in 1983-84, Dr. Mark introduced the microneurographic method for direct intraneural recordings of sympathetic nerve activity into the US and, with his trainees, employed this method to advance understanding of human autonomic control in exercise, heart failure, hypertension, sodium intake and obesity.

His current research addresses mechanisms of obesity-induced hypertension, including the sympathetic actions of leptin and the concept of selective leptin resistance in obese states. With Dr. Robin Davisson at Weill Cornell Medical College, his recent research has focused on the role of endoplasmic reticulum stress in the subfornical organ in obesity and angiotensin induced hypertension in mouse models of obesity and hypertension.

Dr. Mark was Director of the Cardiovascular Division from 1976 to 1995. From 1995 to 2006, he was Associate Dean for Research and Graduate Programs in the Carver College of Medicine. In 2011, he founded and now co-directs the UI Obesity Research and Education Initiative with Dr. Charles Brenner. Dr. Mark held the Roy J. Carver Chair in Internal Medicine from 1993 to 2013. Dr. Mark was the recipient of the 2013 Carver College of Medicine Distinguished Mentor Award.

Center, Program and Institute Affiliations

Cardiovascular Research Center
Center for Functional Genomics of Hypertension
Fraternal Order of Eagles Diabetes Research Center
Obesity Initiative

Date Last Modified: 06/07/2014 - 21:56:23