Dermatology

John C. Selby, MD, PhD, FAAD

Portrait

Assistant Professor of Dermatology

Contact Information

Primary Office: 40033 PFP
200 Hawkins Drive
Iowa City, IA 52242
Primary Office Phone: 319-356-2856

Email: john-selby@uiowa.edu

Education

BS, Mechanical Engineering, Bioengineering Minor, University of Illinois College of Medicine, Urbana-Champaign, Urbana, Illinois
MS, Mechanical Engineering, University of Illinois College of Medicine, Urbana-Champaign, Urbana, Illinois
PhD, Mechanical Engineering, University of Illinois College of Medicine, Urbana-Champaign, Urbana, Illinois
MD, Urbana Campus/University of Illinois College of Medicine, Urbana-Champaign, Urbana, Illinois

Internship, University of Illinois College of Medicine, Urbana-Champaign, Urbana, Illinois
Residency, Dermatology, University of Iowa College of Medicine, Iowa City, Iowa

Licensure and Certifications

State of Iowa Medical License, Iowa Board of Medicine
Board Certified, American Board of Dermatology

Research Summary

RESEARCH AND CLINICAL INTERESTS

My research interests revolve around the field of mechanobiology as it relates to human skin in states of health and disease. In recent collaborative work (Ed Sander, Department of Biomedical Engineering, University of Iowa), my lab has been exploring how the mechanical stiffness of the extracellular matrix can affect the assembly of cell-cell anchoring junctions among human epidermal keratinocytes during the process of de novo epithelial sheet formation. In the future, we plan to explore how manipulation of the mechanical properties of granulation tissue might serve as a therapeutic intervention by which we can increase the rate of re-epithelialization of chronic non-healing wounds (venous stasis ulcers and diabetic ulcers). My clinical interests are centered on the practice of complex medical dermatology, including the diagnosis and management of patients with immunobullous disease, lichen planus, psoriasis, and drug-associated exanthems.

In an age of rapidly progressing interdisciplinary research, advanced knowledge of the human integumentary system garnered both at the bench and the bedside will undoubtedly have a profound impact on the ways in which we will treat skin disease in the years to come.

Selected Publications

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Zarkoob H, Bodduluri S, Ponnaluri S, Selby J, Sander E.  Substrate stiffness affects keratinocyte colony formation.  Cell Mol Bioeng.  2014 September. 

Holahan H, Farah R, Selby J, Fairley J.  Erythema annulare-like acantholytic dermatosis: A subset of pemphigus foliaceus.  Brit J Dermatol.  2014 May 16. 
[PubMed]

Hochwalt P, Asarch A, Selby J, VanBeek M.  Surgical corner. Modified buried suture technique for the scalp.  J Drugs Dermatol.  2013 June. 1(12):692-3.
[PubMed]

Selby J, Liu V.  Cutaneous lymphoid hyperplasia: Cases in Dermatopathology.  Knowledge Books and Software.  2012. 

Selby J.  Mechanobiology of epidermal keratinocytes: Desmosomes, hemidesmosomes, keratin intermediate filaments, and blistering skin diseases.  Springer US.  2011 January 21. 14:169-210.

Selby J, Shannon M.  Inflation of a circular elastomeric membrane into a horizontally semi-infinite liquid reservoir of finite vertical depth: Estimation of material parameters from volume-pressure data.  Int J Eng Sci.  2009 May. 47(5-6):718-34.

Selby J, Shannon M.  Inflation of a circular elastomeric membrane into a horizontally semi-infinite liquid reservoir of finite vertical depth: Quasi-static deformation model.  Int J Eng Sci.  2009 May. 47(5-6):700-17.

Selby J, Shannon M.  A method to fabricate mesoscopic freestanding polydimethylsiloxane membranes used to probe the rheology of an epithelial sheet.  J Biochem Biophs Methods.  2008 April 24. 70(6):932-44.
[PubMed]

Selby J, Shannon M.  Apparatus for measuring the finite load-deformation behavior of a sheet of epithelial cells cultured on a mesoscopic freestanding elastomer membrane.  Rev Sci Instrum.  2007 September. 78(9):094301.
[Link]

Prakash S, Long T, Selby J, Moore J, Shannon M.  ‘Click’ modification of silica surfaces and glass microfluidic channels.  Anal Chem.  2007 February. 79(4):1661-1667.

Date Last Modified: 09/18/2014 - 16:40:04