Pathology

Carol Holman, PhD, MD

Portrait

Mailing Address

Office: 6229 RCP
Iowa City, IA 52242
Phone: +1 319 356 3981
Email: carol-holman@uiowa.edu

Education

BS, Chemistry and Biology, Valparaiso University, 1990
PhD, Biochemistry, University of Illinois, Urbana, 1997
MD, University of Illinois, Urbana, 1999
Residency, Anatomic and Clinical Pathology, University of Minnesota, 2003
Fellowship, Hematopathology, University of Minnesota, 2005

Appointments

Primary: Pathology

Research Summary

Dr. Holman has broad interests in many areas of hematopathology, including clinical diagnosis of patients with leukemia and lymphoma, as well as optimal laboratory testing for detection of minimal residual disease following therapy. She has research interests in the pathogenesis of Epstein-Barr virus infection and its role in a variety of diseases including post-transplant lymphoproliferative disorder, lymphomatoid granulomatosis, and infectious mononucleosis.

Publications

  • Mettler TN, Holman CJ. McKenna RW, Pambuccian SE.  Plasmablastic myeloma in ascitic fluid. Diagn Cytopathol 2011 Jun 22. doi: 10. 1002/dc.21759 [Epub ahead of print]
  • Wudhikarn, K, Holman, C J, Linan, M, Blaes, A H, Dunitz, J M, Hertz, M E, Peterson, B A. Post-transplant lymphoproliferative disorders in lung transplant recipients: 20-yr experience at the University of Minnesota. Clin Transplant 25(5):705-13, 0. [PubMed]
  • Romain CA, Balfour HH, Jr., Vezina, HE, Holman CJ. A method for evaluating antiviral drug susceptibility of Epstein-Barr virus. Virus Adaptation and Treatment 2:1-7, 2010.
  • Dunning, K, Wudhikarn, K, Safo, A, Holman, C, McKenna, R, Pambuccian, S. Adrenal extranodal NK/T-cell lymphoma diagnosed by fine-needle aspiration and cerebrospinal fluid cytology and immunophenotyping: a case report. Diagn Cytopathol 37(9):686-95, 2009. [PubMed]
  • Balfour, H, Hokanson, K, Schacherer, R, Fietzer, C, Schmeling, D, Holman, C, Vezina, H, Brundage, R. A virologic pilot study of valacyclovir in infectious mononucleosis. J Clin Virol 39(1):16-21, 2007. [PubMed]
  • Balfour, H, Holman, C, Hokanson, K, Lelonek, M, Giesbrecht, J, White, D, Schmeling, D, Webb, C, Cavert, W, Wang, D, Brundage, R. A prospective clinical study of Epstein-Barr virus and host interactions during acute infectious mononucleosis. J Infect Dis 192(9):1505-12, 2005. [PubMed]
  • Holman CJ, van Burik JH, Hinrichs SH, Balfour HH, Jr. Specific detection of the human polyomavirus BK in the urine of immunocompromised patients. Clin Diagn Lab Immunol 10 (1): 66-9, 2003
  • Julin, J E, van Burik, J H, Krivit, W, Webb, C, Holman, C J, Clark, H B, Balfour, H H. Ganciclovir-resistant cytomegalovirus encephalitis in a bone marrow transplant recipient. Transpl Infect Dis 4(4):201-6, 2002. [PubMed]
  • Manning, T C, Schlueter, C J, Brodnicki, T C, Parke, E A, Speir, J A, Garcia, K C, Teyton, L, Wilson, I A, Kranz, D M. Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition. Immunity 8(4):413-25, 1998. [PubMed]
  • Schlueter, C J, Manning, T C, Schodin, B A, Kranz, D M. A residue in the center of peptide QL9 affects binding to both Ld and the T cell receptor. J Immunol 157(10):4478-85, 1996. [PubMed]