Neurology

William Talman, MD

Portrait

Mailing Address

Office: S209 GH
Iowa City, IA 52242
Phone: +1 319 356 8750
Email: william-talman@uiowa.edu

Web: Neurobiology and Circulatory Control Laboratory

Education

BA, Virginia Military Institute, Lexington, VA,
MD, University of Virginia School of Medicine,
Internship, Internal Medicine, Case Western Reserve University,
Residency, Internal Medicine, Case Western Reserve University,
Residency, Neurology, Cornell University,
Fellowship, Neurology, Cornell University,

Appointments

Primary: Neurology

Center and Program Affiliations

  • Interdisciplinary Graduate Program in Neuroscience

Research Interests

Central control of circulation, Central neural regulation of cerebral blood flow, Central neurotransmitters, Glycine and acetylcholine interactions in the brain stem, Integration of cardiovascular and noncardiovascular reflexes, Neural modulation of cerebral blood flow, Neurogenic hypertension, Nitrosothiols as central neurotransmitters, The baroreceptor reflex in health and disease, The role of central excitatory amino acid receptors in the baroreceptor reflex

Publications

  • Lin, L, Nitschke Dragon, D, Jin, J, Tian, X, Chu, Y, Sigmund, C, Talman, W. Decreased expression of neuronal nitric oxide synthase in the nucleus tractus solitarii inhibits sympathetically mediated baroreflex responses in rat. J Physiol 590(Pt 15):3545-59, 2012. [PubMed]
  • Lin, L, Nitschke Dragon, D, Talman, W. Collateral damage and compensatory changes after injection of a toxin targeting neurons with the neurokinin-1 receptor in the nucleus tractus solitarii of rat. J Chem Neuroanat 43(2):141-8, 2012. [PubMed]
  • Lin, L, Dragon, D, Jin, J, Talman, W. Targeting neurons of rat nucleus tractus solitarii with the gene transfer vector adeno-associated virus type 2 to up-regulate neuronal nitric oxide synthase. Cell Mol Neurobiol 31(6):847-59, 2011. [PubMed]
  • Taktakishvili, O, Lin, L, Vanderheyden, A, Nashelsky, M, Talman, W. Nitroxidergic innervation of human cerebral arteries. Auton Neurosci 156(1-2):152-3, 2010. [PubMed]
  • Lin, L H, Langasek, J E, Talman, L S, Taktakishvili, O M, Talman, W T. Feline immunodeficiency virus as a gene transfer vector in the rat nucleus tractus solitarii. Cell Mol Neurobiol 30(3):339-46, 2010. [PubMed]
  • Boysen, N, Dragon, D, Talman, W. Parasympathetic tonic dilatory influences on cerebral vessels. Auton Neurosci 147(1-2):101-4, 2009. [PubMed]
  • Nayate, A, Moore, S, Weiss, R, Taktakishvili, O, Lin, L, Talman, W. Cardiac damage after lesions of the nucleus tractus solitarii. Am J Physiol Regul Integr Comp Physiol 296(2):R272-9, 2009. [PubMed]
  • Lin, L H, Taktakishvili, O M, Talman, W T. Colocalization of neurokinin-1, N-methyl-D-aspartate, and AMPA receptors on neurons of the rat nucleus tractus solitarii. Neuroscience 154(2):690-700, 2008. [PubMed]
  • Talman, W, Nitschke Dragon, D. Neuronal nitric oxide mediates cerebral vasodilatation during acute hypertension. Brain Res 1139:126-32, 2007. [PubMed]
  • Talman, W, Corr, J, Nitschke Dragon, D, Wang, D. Parasympathetic stimulation elicits cerebral vasodilatation in rat. Auton Neurosci 133(2):153-7, 2007. [PubMed]