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Address: 540 EMRB
Phone: (319) 335-7996
Mentor: Alexander R. Horswill, PhD
Undergraduate Institution: University of Wisconsin-Madison
Research in the Horswill Laboratory centers around the bacterial pathogen Staphylococcus aureus. My studies have focused on the roles of the secreted enzyme hyaluronate lyase, encoded by the gene hysA, in S. aureus physiology and pathogenesis. Specifically, I am interested in how HysA is regulated, its overall contribution to S. aureus virulence and whether it is involved in various staphylococcal physiologic processes.
Walker JN, Crosby HA, Spaulding AR, Salgado-Pabón W, Malone CL, Rosenthal CB, Schlievert PM, Boyd JM, Horswill AR. The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis. PLOS Pathogens. 2013 9(12), e1001381
Rosenthal, Carolyn B., Joe M. Mootz, and Alexander R. Horswill. "Staphylococcus aureus Biofilm Formation and Inhibition." Antibiofilm Agents. Springer Berlin Heidelberg, 2014. 233-255.
Ibberson CB, Jones CL, Singh S, Wise MC, Zurawski DV, Horswill AR. Staphylococcus aureus hyaluronidase is a CodY-regulated virulence factor. Infect Immun. 2014
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