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UI Carver College of Medicine
451 Newton Road
200 Medicine Administration Building
Iowa City, IA 52242
Local Phone: (319) 335-6707
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Carver College of Medicine
Research
Protein Crystallography Facility
Protein Crystallography Facility
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Services
Assistance with protein purification for crystallization
Protein purity analysis by dynamic and static light scattering
Set-up of crystallization screens using commercial and facility-made conditions
Preliminary screening of crystals
Data collection of quality crystals at facility x-ray source and synchrotrons
Data processing using popular packages such as d*TREK, XDS and mosflm
Structure determination using MR, MIR, MAD, SAD, techniques and software such as ccp4, Phenix, phaser, SHELX, SHARP/autoSHARP
Structure refinement and fitting using Refmac, Phenix, Coot, O
Structure visualization and analysis using PyMol, VMD, Chimera, Sybyl