Other Information

IgM

L04260

mRNA

Sequences differ by 19 nt (including a 6 nt insert) suggesting the presence of two different allotypes

μ?

X59994

mRNA

IgD

δ

AF515673

mRNA

Surface IgD

δ

AF411238

mRNA

Secreted IgD

IgG1

γ1

mRNA

IgG2

γ2

mRNA

IgE

ε

M84356

mRNA

IgA

α

mRNA

Description

GenBank
Accession Number

Sequence
Source

Other Information

Cκ

X54110

mRNA

Cλ1

AY734681

mRNA

Used with Jλ1 rearrangements

Cλ2

AY734682

mRNA

Used with Jλ2 rearrangements – premature STOP codon at nt 124-126

Description

H Family

GenBank
Accession Number

Other Information

VG1U

1

Z49180

Derived from PCR.

VGE7U

1

Z49181

VGE6U

1

Z49182

VG5U

1

Z49183

Derived from PCR. Likely pseudogenes (11 nt deletion in leader sequence). VG5U also lacks the ATG START codon.

VG2U

1

Z49184

VG10U

1

Z49185

V7A

1

Z49186

Obtained from genomic library.

V5A

1

Z49187

V1B

1

Z49188

Description

GenBank
Accession Number

Functional

Other Information

pseudo-JH1

Z71572

No

Defective RSS

pseudo-JH2

No

Defective RSS

pseudo-JH3

No

Defective RSS

pseudo-JH4

No

Defective RSS & non-optimal reading frame

JH1

Yes

JH1 appears to be 2 codons shorter than JH2

JH2

Yes

Description

k Family

GenBank
Accession Number

Other Information

kappa-1

I

AF038133

Comparable use to kappa-3,4 in early fetal life but reduced rearrangement in later stages of development.

kappa-2.1

II

AF038134

kappa-2.2

II

AF038135

kappa-2.3

II

AF038136

kappa-3

III

AF038137

Dominate the rearranged Vκ pool in late fetal development.

kappa-4

IV

AF038138

Description

GenBank
Accession Number

Functional

Other Information

Jκ1

AF038132

Yes

PCR amplified from genomic DNA

Jκ2

No ?

Poor match to a consensus RSS

Jκ3

Yes

PCR amplified from genomic DNA

Jλ1

M60440

Yes

Predominant J in diversified repertoire

Jλ2

Jeong et al. [10]

Yes

Frequent in early but not late fetal development

Description

λ Family

GenBank Accession Number

Functional

Other Information

Vλ 1.2

IV

AF40900

Yes

Derived from genomic library

Vλ 1.3

I

AF40901

Yes

Vλ 10

IV

AF40902

Yes

Vλ 12.1

V

AF40903

No (FS del 158)

Vλ 12.2

I

AF40904

Yes

Vλ 16.1

I

AF40905

Yes

Vλ 16.2

V

AF40906

No (FS del 370)

Vλ 17

IV

AF40907

Yes

Vλ 18

I

AF40908

Yes

Vλ 2.1

I

AF40909

Yes

Vλ 2.2

V

AF40910

No (2FS del 307)

Vλ 26.1

I

AF40911

Yes

Vλ 26.2

V

AF40912

No (FS del 370)

Vλ 26.3

I

AF40913

Yes

Vλ 3.1

III

AF40914

Yes

Vλ 3

I

AF40915

Yes

Vλ 4.1

I

AF40916

Yes

Vλ 4.2

IV

AF40917

Yes

Vλ 5.2

IV

AF40918

Yes

Vλ 5.3

I

AF40919

Yes

Vλ 5.4

I

AF40920

Yes

Vλ6.1

II

AF40921

Yes

Vλ 6.2

II

AF40922

Yes

Vλ 8.0

IV

AF40923

Yes

Vλ 9

IV

AF40924

Yes

Vλ 5.1

I

M60441

Yes

Vλ 4.1.1

I

AY158468

Yes

Derived from PCR amplification of rearranged genomic DNA

Vλ 4.1.2

I

AY158469

Yes

Vλ 4.1.3

I

AY158470

Yes

Vλ 4.1.4

I

AY158471

Yes

Vλ4.1.5

I

AY158472

Yes

Vλ 4.1.6

I

AY158473

Yes

Vλ 4.1.7

I

AY158474

Yes

Vλ 4.1.8

I

AY158475

Yes

Vλ 5.4.1

I

AY158476

Yes

Vλ 5.4.2

I

AY158477

Yes

Vλ 5.4.3

I

AY158478

Yes

Vλ5.4.4

I

AY158479

Yes

Vλ 5.4.5

I

AY158480

Yes

Vλ 5.4.6

I

AY158481

Yes

Vλ 5.4.7

I

AY158482

Yes

Vλ 5.4.8

I

AY158483

Yes

Vλ 5.4.9

I

AY158484

Yes

Vλ 5.4.10

I

AY158485

Yes

Vλ 5.4.11

I

AY158486

Yes

Vλ5.4.12

I

AY158487

Yes

Vλ5.3.1

I

AY158488

Yes

Vλ 5.3.2

I

AY158489

Yes

Vλ 5.3.3

I

AY158490

Yes

Vλ 5.3.4

I

AY158491

Yes

Vλ 5.3.5

I

AY158492

Yes

Vλ 5.3.6

I

AY158493

Yes

Vλ 5.3.7

I

AY158494

Yes

Vλ 5.3.8

I

AY158495

Yes

Vλ 5.3.9

I

AY158496

Yes

Vλ 5.1.1

I

AY158497

Yes

Vλ 5.1.2

I

AY158498

Yes

Vλ5.1.3

I

AY158499

Yes

Vλ 5.1.4

I

AY158500

Yes

Vλ 5.1.5

I

AY158501

Yes

Vλ 5.1.6

I

AY158502

Yes

Vλ 5.1.7

I

AY158503

Yes

Vλ 5.1.8

I

AY158504

Yes

Vλ5.1.9

I

AY158505

Yes

Vλ5.1.10

I

AY158506

Yes

Vλ 5.1.11

I

AY158507

Yes

Vλ 5.1.12

I

AY158508

Yes

Vλ 5.1.13

I

AY158509

Yes

Vλ 5.1.14

I

AY158510

Yes

Vλ 5.1.15

I

AY158511

Yes

Vλ 5.1.16

I

AY158512

Yes

Vλ 5.1.17

I

AY158513

Yes

Vλ 5.1.18

I

AY158514

Yes

Vλ 5.1.19

I

AY158515

Yes

Vλ 3.0.1

I

AY158516

Yes

Vλ 3.0.2

I

AY158517

Yes

Vλ 3.0.3

I

AY158518

Yes

Vλ 3.0.4

I

AY158519

Yes

Vλ3.0.5

I

AY158520

Yes

Vλ 3.0.6

I

AY158521

Yes

Vλ 3.0.7

I

AY158522

Yes

Vλ 3.0.8

I

AY158523

Yes

Vλ 3.0.9

I

AY158524

Yes

Vλ 3.0.10

I

AY158525

Yes

Vλ 3.0.11

I

AY158526

Yes

Vλ 3.0.12

I

AY158527

Yes

Vλ 3.0.13

I

AY158528

Yes

Vλ 3.0.14

I

AY158529

Yes

Vλ 3.0.15

I

AY158530

Yes

Vλ 3.0.16

I

AY158531

Yes

lambda-1a

I

AF038139

Yes

From PCR amplification of splenic or peripherial blood lymphocyte (PBL) derived cDNA

lambda-1c

I

AF038140

Yes

lambda-1d

I

AF038141

Yes

lambda-1e

I

AF038142

Yes

lambda-2b

II

AF038143

Yes

lambda-2c

II

AF038144

Yes

lambda-6a

VI

AF038145

Yes

lambda-6b

VI

AF038146

Yes

lambda-6c

VI

AF038147

Yes

lambda-6d

VI

AF038148

Yes