Equine CH Nomenclature1 [6/20/2002]
| Original Description | Current Designation | Chain & Allotype | Gene | Serological Allele | Sequence Allele | GenBank Acc. # | Major Features and Other Information |
| IgGa | IgG1 | g1 | IGHG1 | AJ302055 | |||
| IgG2 | g2 | IGHG2 | AJ302056 | ||||
| IgG(T) | IgG3 | g3 | IGHG3 | ||||
| IgGb | IgG4a | g4a | IGHG4 | AJ302057 | |||
| IgG4b | g4b | IGHG4 | AJ302058 | ||||
| IgG5 | g5 | IGHG5 | |||||
| IgG6 | g6 | IGHG6 | |||||
| IgA | IgA | a | IGHA | ||||
| IgM | IgM | m | IGHM | L49414 | |||
| IgE | IgEa | ea | IGHE | AJ305946 AJ305047 | Trp41, Leu239 | ||
| IgEb | eb | IGHE | AJ305048 | Arg41, Met239 | |||
| IgEc | ec | IGHE | U15150 | 22 aa substitutions abd 5 aa deletions, compared to IgEa and IgEb. |
References
Montgomery P.C. 1973. Molecular aspects of equine antibodies. In: Proceedings of the 3rd International Conference on Equine Infectious Diseases (Edited by Bryans J.T. and Gerber H.), pp 343-363. Karger, Basel.
Navarro, P., D.P. Barbis, D. Antczak and J.E. Butler. 1995. The complete cDNA and deduced amino acid sequence of equine IgE. Mol. Immunol. 32: 1-8.
Rockey, J.H. 1967. Equine antihapten antibody. The subunits and fragments of anti-lactoside antibody. J. Exp. Med., 125: 249-275.
Schrenzel, M.D., D.P. King, M.L. McKnight and D.A. Ferrick. 1997. Characterization of horse (Equus caballus) immunoglobulin mu chain-encoding genes. Immunogenetics, 45: 386-393.
Suter, M. and H. Fey. 1981. Isolation and characterization of horse IgE. Zbl. Vet. Med. B 28: 414-420.
Vaerman J.P., P. Querinjean and J.F. Heremans. 1971. Studies on the IgA system of the horse. Immunology, 21: 443-454.
Wagner, B., G. Siebenkotten, W. Leibold and A. Radbruch. 1997. Organization of the equine immunoglobulin constant heavy chain genes. I. ce and ca genes. Vet. Immunol. Immunopathol., 60: 1-13.
Wagner, B., G. Overesch, A.S. Sheoran, M.A. Holmes, C. Richards, W. Leibold and A. Radbruch. 1998. Organization of the equine immunoglobulin heavy chain constant region genes. III. Alignment of cµ, cg , ce and ca genes. Immunobiol., 199: 105-119.
Overesch, G., B. Wagner, A. Radbruch and W. Leibold. 1998. Organization of the equine immunoglobulin constant heavy chain genes. II. Equine cg genes. Vet Immunol. Immunopathol., 66: 273-287.
Biological Properties: