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Nomenclature:

Equine CH Nomenclature1            [6/20/2002]

Original Description Current Designation Chain & Allotype Gene Serological  Allele Sequence  Allele GenBank Acc. #  Major Features and Other Information
IgGa IgG1 g1 IGHG1 AJ302055
  IgG2 g2 IGHG2     AJ302056  
IgG(T) IgG3  g3  IGHG3         
IgGb IgG4a  g4a  IGHG4      AJ302057  
  IgG4b  g4b  IGHG4     AJ302058   
  IgG5  g5 IGHG5        
  IgG6  g6 IGHG6        
IgA IgA a IGHA        
IgM IgM m IGHM     L49414  
IgE IgEa ea IGHE     AJ305946 AJ305047 Trp41, Leu239
  IgEb eb IGHE     AJ305048 Arg41, Met239
  IgEc ec IGHE     U15150 22 aa substitutions abd 5 aa deletions, compared to IgEa and IgEb.

 

References

Montgomery P.C. 1973. Molecular aspects of equine antibodies. In: Proceedings of the 3rd International Conference on Equine Infectious Diseases (Edited by Bryans J.T. and Gerber H.), pp 343-363. Karger, Basel.

Navarro, P., D.P. Barbis, D. Antczak and J.E. Butler. 1995. The complete cDNA and deduced amino acid sequence of equine IgE. Mol. Immunol. 32: 1-8.

Rockey, J.H. 1967. Equine antihapten antibody. The subunits and fragments of anti-lactoside antibody. J. Exp. Med., 125: 249-275.

Schrenzel, M.D., D.P. King, M.L. McKnight and D.A. Ferrick. 1997. Characterization of horse (Equus caballus) immunoglobulin mu chain-encoding genes. Immunogenetics, 45: 386-393.

Suter, M. and H. Fey. 1981. Isolation and characterization of horse IgE. Zbl. Vet. Med. B 28: 414-420.

Vaerman J.P., P. Querinjean and J.F. Heremans. 1971. Studies on the IgA system of the horse. Immunology, 21: 443-454.

Wagner, B., G. Siebenkotten, W. Leibold and A. Radbruch. 1997. Organization of the equine immunoglobulin constant heavy chain genes. I. ce and ca genes. Vet. Immunol. Immunopathol., 60: 1-13.

Wagner, B., G. Overesch, A.S. Sheoran, M.A. Holmes, C. Richards, W. Leibold and A. Radbruch. 1998. Organization of the equine immunoglobulin heavy chain constant region genes. III. Alignment of cµ, cg , ce and ca genes. Immunobiol., 199: 105-119.

Overesch, G., B. Wagner, A. Radbruch and W. Leibold. 1998. Organization of the equine immunoglobulin constant heavy chain genes. II. Equine cg genes. Vet Immunol. Immunopathol., 66: 273-287.

 

 

 

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