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Biosciences Program Faculty performing Molecular & Cellular Biology research
Molecular biology research at the University of Iowa includes laboratories in the Molecular Biology PhD Program and other programs on campus.
The ability to analyze and alter gene expression has become a central focus of a great deal of biological research. Scientists within many different disciplines are increasingly using molecular biological approaches in cell and animal models to gain new understanding of fundamental processes.
To meet this need the interdisciplinary graduate program in molecular biology provides a core component of molecular and cell biology training which is complemented by course work and thesis research in various areas:
· Molecular Medicine
· Virology
· Signal Transduction
· Gene Regulation
The university-wide nature of this program permits training and research opportunities in the laboratories of faculty anatomy and cell biology, biochemistry, biological sciences, internal medicine, microbiology, pathology, pediatrics, pharmacology, physiology and biophysics, radiology, and ophthalmology. |
| Name |
Rank |
Department/
Program |
Research
Description |
|
Apicella, Michael, MD |
Professor (Head) |
Microbiology Immunology Molecular & Cellular Biology
|
Understanding of the molecular basis of the human immune response to Neisseria and Haemophilus to improve vaccine technology. |
|
Artemyev, Nikolai, PhD |
Professor |
Molecular Physiology & Biophysics Molecular & Cellular Biology
|
Mechanisms of G-protein signaling |
|
Bickenbach, Jackie, PhD |
Professor |
Anatomy & Cell Biology Dermatology Pathology Genetics Molecular & Cellular Biology
|
Activation of embryonic transcription factors in epidermal stem cells and the dynamics of dedifferentiation in cancer biology and wound healing |
|
Bishop, Gail, PhD |
Professor |
Microbiology Internal Medicine Immunology Molecular & Cellular Biology
|
Molecular mechanisms of lymphocyte activation; role in normal immunity, autoimmunity, and lymphoma. |
|
Bonthius, Daniel, MD/PhD |
Professor |
Pediatrics Neurology Molecular & Cellular Biology Neuroscience Medical Scientist Training Program
|
Abnormalities of brain development, including fetal alcohol syndrome and congenital viral infections |
|
Butler, John, PhD |
Professor |
Microbiology Immunology
|
Developmental Immunology; Antibody and T cell repertoire development; role of colonization and viral infection on antibody and T cell repertoire diversification |
|
Chen, Songhai, MD/PhD |
Assistant Professor |
Pharmacology
|
G protein-dependent signaling mechanisms of leukocyte migration and tumor metastasis |
|
Cheng, Chi-Lien, PhD |
Associate Professor |
Biology Genetics
|
Alternation of generations in land plants |
|
Clegg, Steven, PhD |
Professor |
Microbiology
|
Molecular biology of enterobacterial adhesions |
|
Cohen, Michael, MD |
Professor |
Pathology Urology Epidemiology Molecular & Cellular Biology
|
Receptor-ligand-mediated cell death in prostate cancer |
|
Colgan, John, PhD |
Assistant Professor |
Internal Medicine Anatomy & Cell Biology Immunology Molecular & Cellular Biology
|
Signal transduction pathways that control of the development and function of lymphocytes |
|
Davidson, Beverly, PhD |
Professor |
Internal Medicine Neurology Molecular Physiology & Biophysics Genetics Molecular & Cellular Biology Neuroscience
|
Molecular and cellular mechanisms of CNS dysfunction in metabolic diseases and gene transfer to the CNS |
|
DeMali, Kris, PhD |
Assistant Professor |
Biochemistry Molecular & Cellular Biology
|
Cellular mechanisms involved in assembly and maintenance of cell-cell adhesions by examining the function and regulation of proteins recruited to the cytoplasmic face of cadherins |
|
Domann, Frederick, PhD |
Professor |
Radiation Oncology Free Radical & Radiation Biology Human Toxicology Molecular & Cellular Biology
|
DNA methylation and oncogenes, Ras and Cancer, Redox regulation of AP-2 |
|
Donelson, John, PhD |
Professor |
Biochemistry
|
Molecular biology of parasites that cause tropical diseases |
|
Dupuy, Adam, PhD |
Assistant Professor |
Anatomy & Cell Biology Genetics Molecular & Cellular Biology
|
Developing new mouse models of human cancer using the Sleeping Beauty transposon system |
|
Engelhardt, John, PhD |
Professor (Head) |
Anatomy & Cell Biology Internal Medicine Free Radical & Radiation Biology Molecular & Cellular Biology
|
Molecular/cellular biology and gene therapy of inherited and environmental diseases |
|
England, Sarah, PhD |
Professor |
Molecular Physiology & Biophysics Molecular & Cellular Biology
|
Molecular mechanisms regulating potassium channel function during pregnancy and vascular dysfunction |
|
Feiss, Michael, PhD |
Professor |
Microbiology Genetics Molecular & Cellular Biology
|
Virus DNA packaging: mechanistic studies using phage lambda |
|
Fritzsch, Bernd, PhD |
Professor (Chair) |
Biology Otolaryngology
|
The molecular basis of ear neurosensory development with the aim to improve longevity of sensory neurons and ultimately restore hearing. |
|
Fuentes, Ernesto, PhD |
Assistant Professor |
Biochemistry Center for Biocatalysis & Bioprocessing Training Program in the Pharmacological Sciences Molecular & Cellular Biology
|
Molecular mechanisms governing specific signal transduction pathways |
|
Gardinier, Minnetta, PhD |
Professor |
Pharmacology
|
Oligodendroglial cell biology and CNS myelination |
|
Geyer, Pamela, PhD |
Professor |
Biochemistry Genetics Molecular & Cellular Biology
|
Role of chromosome structure and organization on gene expression in Drosophila |
|
Giangrande, Paloma, PhD |
Assistant Professor |
Internal Medicine Molecular & Cellular Biology
|
Developing RNA-based therapeutics to modulate cellular pathways underlying pathological cell proliferation in the setting of cancer and cardiovascular disease. |
|
Goswami, Prabhat, PhD |
Associate Professor |
Radiation Oncology Free Radical & Radiation Biology Human Toxicology Molecular & Cellular Biology
|
Intracellular Redox Environment and the Mammalian Cell Cycle |
|
Green, Steven, PhD |
Professor |
Biology Otolaryngology Molecular & Cellular Biology Neuroscience
|
Intracellular signaling: signal transduction for neurotrophic stimuli |
|
Habelhah, Hasem, PhD |
Assistant Professor |
Pathology Molecular & Cellular Biology
|
The role of TRAF2 phosphorylation in NF-?B activation and cancer cell resistance to apoptosis |
|
Heusel, Jonathan, MD/PhD |
Assistant Professor |
Pathology Immunology
|
Molecular parameters of natural killer (NK) cell activation in the settings of viral infection, cancer, and allogeneic hematopoietic stem cell transplantation |
|
Hohl, Raymond, MD/PhD |
Professor |
Internal Medicine Pharmacology Molecular & Cellular Biology
|
Role of Isoprene Compounds in Cell Proliferation and Differentiation |
|
Horswill, Alexander, PhD |
Assistant Professor |
Microbiology
|
Bacterial cell-to-cell communication using autoinducing peptides |
|
Houston, Douglas, PhD |
Assistant Professor |
Biology Genetics Neuroscience
|
Maternal transcription factor and signalling pathways in vertebrate development |
|
Ianzini, Fiorenza, PhD |
Assistant Professor |
Pathology Radiation Oncology and Biomedical Engineering Free Radical & Radiation Biology
|
Molecular Regulators of Cell Cycle Progression and Radiation- and Anticancer Drug-Induced Mitotic Catastrophe in Cancer Promotion and Progression |
|
Janz, Siegfried, MD |
Professor |
Pathology Immunology
|
Mouse models of human B cell and plasma cell neoplasms |
|
Jones, Bradley, PhD |
Associate Professor |
Microbiology Genetics
|
Bacteria-host cell interactions of Salmonella pathogenesis; Francisella pathogenesis |
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Khademi, Shahram, PharmD/PhD |
Assistant Professor |
Biochemistry Molecular Physiology & Biophysics
|
Structure and function of membrane proteins using X-ray crystallography techniques |
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Kitamoto, Toshihiro, PhD |
Assistant Professor |
Anesthesia Neurology Genetics Neuroscience
|
Genetics of complex behavior |
|
Klingelhutz, Al, PhD |
Associate Professor |
Microbiology Free Radical & Radiation Biology Genetics Molecular & Cellular Biology
|
Mechanisms of cellular immortalization and transformation by human papillomavirus |
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Kohen, Amnon, PhD |
Associate Professor |
Chemistry Molecular & Cellular Biology
|
The role of protein dynamics and quantum mechanical effects in enzyme catalyzed hydrogen transfer and the mechanism of dinitrogen reduction by nitrogenases |
|
Kuwana, Tomomi, PhD |
Assistant Professor |
Pathology Molecular & Cellular Biology
|
Mitochondrial regulation of apoptosis |
|
Legge, Kevin, PhD |
Assistant Professor |
Pathology Immunology
|
Dendritic Cell Immunobiology and Pulmonary Immunity |
|
Lentz, Steven, MD/PhD |
Professor |
Internal Medicine Molecular & Cellular Biology
|
Vascular Cell Biology and Regulation of Hemostasis |
|
Levasseur, Dana, PhD |
Assistant Professor |
Internal Medicine Molecular & Cellular Biology
|
Transcriptional and epigenetic regulation of embryonic stem cell function and pluripotent stem cell biology |
|
Lidral, Andrew, PhD/DDS |
Professor |
Orthodontics Genetics Molecular & Cellular Biology
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Craniofacial developmental genetics |
|
Lin, Jim (Chung-Jung), PhD |
Professor |
Biology Genetics Molecular & Cellular Biology
|
Structure and function of protein components of the cytoskeleton; molecular mechanisms of cardiac morphogenesis |
|
Logsdon, John, PhD |
Associate Professor |
Biology Genetics Molecular & Cellular Biology
|
Evolutionary Molecular Genetics/Genomics: Origins and Evolution of
Meiosis, Lateral Gene Transfer, Phylo-informatics |
|
Maury, Wendy, PhD |
Associate Professor |
Microbiology Molecular & Cellular Biology
|
Regulation of lentiviral cell tropism |
|
McCaffrey, Anton, PhD |
Assistant Professor |
Internal Medicine Genetics Molecular & Cellular Biology
|
Role of RNA in human disease and the development of nucleic acid based therapeutics |
|
McCarter, Linda, PhD |
Professor |
Microbiology
|
Surface sensing, signal transduction, biofilm formation, and regulation of gene expression and differentiation in bacteria |
|
McGowan, Stephen, MD |
Professor |
Internal Medicine Molecular & Cellular Biology
|
Connective tissue biochemistry in the lung |
|
Meier, Jeffrey, MD |
Associate Professor |
Internal Medicine Molecular & Cellular Biology
|
Viral pathogenesis at the molecular level |
|
Menninger, John, PhD |
Professor |
Biology Genetics Molecular & Cellular Biology
|
Accuracy of Translation; Cellular Aging; mRNA/Ribosome co-evolution |
|
Moye-Rowley, Scott, PhD |
Professor |
Molecular Physiology & Biophysics Genetics Molecular & Cellular Biology
|
Transcriptional control of oxidative stress tolerance; eukaryotic multidrug resistance |
|
Murray, Jeffrey, MD |
Professor |
Pediatrics Biology Epidemiology Genetics Molecular & Cellular Biology
|
Studies of human gene-environment interactions |
|
Nagy, Peter, MD/PhD |
Assistant Professor |
Pathology Biochemistry Genetics
|
Histone methylation |
|
Price, David, PhD |
Professor |
Biochemistry Molecular & Cellular Biology
|
Eucaryotic gene regulation elongation control of RNA polymerase II |
|
Quelle, Dawn, PhD |
Associate Professor |
Pharmacology Molecular & Cellular Biology
|
Signaling pathways activated by the ARF & p53 tumor suppressors; molecular control of growth |
|
Quelle, Frederick, PhD |
Associate Professor |
Pharmacology Immunology
|
Cytokine receptor signal transduction mechanisms regulating cell growth and survival |
|
Roller, Richard, PhD |
Professor |
Microbiology Molecular & Cellular Biology
|
Function of herpes simplex virus membrane proteins in virus entry, exit from the cell and apoptosis regulation |
|
Rothman, Paul, MD |
Professor (Head) |
Internal Medicine Microbiology Molecular Physiology & Biophysics Immunology
|
Regulation of Cytokine Signaling |
|
Rubenstein, Peter, PhD |
Professor |
Biochemistry Internal Medicine Molecular & Cellular Biology
|
Biochemical and biophysical basis of actin function; role of actin in maintenance of yeast mitochondrial function |
|
Russo, Andrew, PhD |
Professor |
Molecular Physiology & Biophysics Genetics Molecular & Cellular Biology Neuroscience
|
Control of neuronal gene expression |
|
Rutkowski, Tom, PhD |
Assistant Professor |
Anatomy & Cell Biology Molecular & Cellular Biology
|
Mechanisms of adaptation to chronic cellular stresses in physiology and disease |
|
Sheff, David, MD/PhD |
Assistant Professor |
Pharmacology Molecular & Cellular Biology
|
Intracellular Membrane Traffic and Receptor Sorting in the Endosomal System |
|
Shih, Ming-Che, PhD |
Professor |
Biology
|
Gene regulation of plant metabolism |
|
Sigmund, Curt, PhD |
Professor |
Internal Medicine Molecular Physiology & Biophysics Genetics Molecular & Cellular Biology Neuroscience
|
Molecular genetics and molecular biology of the renin-angiotensin system and hypertension. Cardiovascular biology. |
|
Soll, David, PhD |
Professor |
Biology
|
Molecular Pathology and Cell Motility |
|
Stamnes, Mark, PhD |
Associate Professor |
Molecular Physiology & Biophysics Molecular & Cellular Biology
|
Molecular mechanisms of intracellular protein transport and sorting in the mammalian Golgi apparatus |
|
Stauffer, George, PhD |
Professor |
Microbiology
|
Mechanisms of bacterial gene transcription |
|
Stoltzfus, C. Martin, PhD |
Professor |
Microbiology Molecular & Cellular Biology
|
HIV RNA splicing regulation |
|
Stone, Edwin, MD/PhD |
Professor |
Ophthalmology & Visual Sciences Genetics
|
Molecular genetics of inherited eye diseases |
|
Strack, Stefan, PhD |
Associate Professor |
Pharmacology Molecular & Cellular Biology Neuroscience
|
Protein phosphatases in neuronal signal transduction and disease |
|
Sutterwala, Fayyaz, MD/PhD |
Assistant Professor |
Internal Medicine Immunology Molecular & Cellular Biology
|
Biology of the NOD-like receptor family in infection and inflammation. |
|
Tan, Kai, PhD |
Assistant Professor |
Internal Medicine Biomedical Engineering Genetics
|
Understanding gene regulatory networks and molecular pathways in human diseases |
|
Thomas, Christie, MD |
Professor |
Internal Medicine Molecular & Cellular Biology
|
Organization and regulation of the epithelial sodium channel, sgk1 and Nedd4-2 |
|
Tootle, Tina, PhD |
Assistant Professor |
Anatomy & Cell Biology
|
The Tootle lab studies the molecular mechanisms by which prostaglandins mediate actin dynamics and cell migration during Drosophila oogenesis. |
|
Turek, Lubomir, MD |
Professor |
Pathology Molecular & Cellular Biology
|
Molecular biology and epidemiology of human papillomavirus in infection and cancer |
|
Wallrath, Lori, PhD |
Professor |
Biochemistry Genetics Molecular & Cellular Biology
|
The role of chromatin proteins in disease |
|
Washington, M. Todd, PhD |
Associate Professor |
Biochemistry Molecular & Cellular Biology
|
Understanding the mechanisms of DNA polymerases involved in both mutagenic and error-free replication of DNA damage at the thermodynamic, kinetic, and structural level |
|
Weeks, Daniel, PhD |
Professor |
Biochemistry Molecular & Cellular Biology
|
Molecular mechanisms of early embryogenesis, cardiogenesis, and the development of novel oligonucleotide based stratagies to investigate control of development |
|
Weiss, David, PhD |
Associate Professor |
Microbiology Genetics
|
Cell division and protein localization in bacteria |
|
Welsh, Michael, MD |
Professor |
Internal Medicine Molecular Physiology & Biophysics Genetics Molecular & Cellular Biology Neuroscience
|
Biology of cystic fibrosis; structure and fuction of ion channels; pathogenesis of lung disease |
|
Wilson, Mary, MD |
Professor |
Internal Medicine Microbiology Epidemiology Genetics Immunology Molecular & Cellular Biology
|
Immunobiology, genetics, and molecular biology of visceral leishmaniasis in murine and human hosts |
|
Wold, Marc, PhD |
Professor |
Biochemistry Molecular & Cellular Biology
|
Molecular mechanisms of eukaryotic chromosomal DNA replication |
|
Xing, Yi, PhD |
Assistant Professor |
Internal Medicine Biomedical Engineering Genetics
|
Bioinformatics of RNA splicing and alternative splicing, comparative genomics, and microarray data analysis. |
|
Yeaman, Charles, PhD |
Associate Professor |
Anatomy & Cell Biology Molecular & Cellular Biology
|
Cell mechanisms involved in development and maintenance of epithelial cell polarity |
|
Zabner, Joseph, MD |
Professor |
Internal Medicine Molecular & Cellular Biology
|
Gene transfer to human airway epithelia in particular developing gene therapy for cystic fibrosis |
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