Biosciences Program Faculty performing Molecular & Cellular Biology research

Molecular biology research at the University of Iowa includes laboratories in the Molecular Biology PhD Program and other programs on campus.

The ability to analyze and alter gene expression has become a central focus of a great deal of biological research. Scientists within many different disciplines are increasingly using molecular biological approaches in cell and animal models to gain new understanding of fundamental processes.

To meet this need the interdisciplinary graduate program in molecular biology provides a core component of molecular and cell biology training which is complemented by course work and thesis research in various areas:

· Molecular Medicine
· Virology
· Signal Transduction
· Gene Regulation

The university-wide nature of this program permits training and research opportunities in the laboratories of faculty anatomy and cell biology, biochemistry, biological sciences, internal medicine, microbiology, pathology, pediatrics, pharmacology, physiology and biophysics, radiology, and ophthalmology.

Name

Rank

Department/
Program
Research Description
Apicella, Michael, MD Professor (Head) Microbiology
Immunology
Molecular & Cellular Biology
Understanding of the molecular basis of the human immune response to Neisseria and Haemophilus to improve vaccine technology.
Artemyev, Nikolai, PhD Professor Molecular Physiology & Biophysics
Molecular & Cellular Biology
Mechanisms of G-protein signaling
Bickenbach, Jackie, PhD Professor Anatomy & Cell Biology
Dermatology
Pathology
Genetics
Molecular & Cellular Biology
Activation of embryonic transcription factors in epidermal stem cells and the dynamics of dedifferentiation in cancer biology and wound healing
Bishop, Gail, PhD Professor Microbiology
Internal Medicine
Immunology
Molecular & Cellular Biology
Molecular mechanisms of lymphocyte activation; role in normal immunity, autoimmunity, and lymphoma.
Bonthius, Daniel, MD/PhD Professor Pediatrics
Neurology
Molecular & Cellular Biology
Neuroscience
Medical Scientist Training Program
Abnormalities of brain development, including fetal alcohol syndrome and congenital viral infections
Butler, John, PhD Professor Microbiology
Immunology
Developmental Immunology; Antibody and T cell repertoire development; role of colonization and viral infection on antibody and T cell repertoire diversification
Chen, Songhai, MD/PhD Assistant Professor Pharmacology
G protein-dependent signaling mechanisms of leukocyte migration and tumor metastasis
Cheng, Chi-Lien, PhD Associate Professor Biology
Genetics
Alternation of generations in land plants
Clegg, Steven, PhD Professor Microbiology
Molecular biology of enterobacterial adhesions
Cohen, Michael, MD Professor Pathology
Urology
Epidemiology
Molecular & Cellular Biology
Receptor-ligand-mediated cell death in prostate cancer
Colgan, John, PhD Assistant Professor Internal Medicine
Anatomy & Cell Biology
Immunology
Molecular & Cellular Biology
Signal transduction pathways that control of the development and function of lymphocytes
Davidson, Beverly, PhD Professor Internal Medicine
Neurology
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Molecular and cellular mechanisms of CNS dysfunction in metabolic diseases and gene transfer to the CNS
DeMali, Kris, PhD Assistant Professor Biochemistry
Molecular & Cellular Biology
Cellular mechanisms involved in assembly and maintenance of cell-cell adhesions by examining the function and regulation of proteins recruited to the cytoplasmic face of cadherins
Domann, Frederick, PhD Professor Radiation Oncology
Free Radical & Radiation Biology
Human Toxicology
Molecular & Cellular Biology
DNA methylation and oncogenes, Ras and Cancer, Redox regulation of AP-2
Donelson, John, PhD Professor Biochemistry
Molecular biology of parasites that cause tropical diseases
Dupuy, Adam, PhD Assistant Professor Anatomy & Cell Biology
Genetics
Molecular & Cellular Biology
Developing new mouse models of human cancer using the Sleeping Beauty transposon system
Engelhardt, John, PhD Professor (Head) Anatomy & Cell Biology
Internal Medicine
Free Radical & Radiation Biology
Molecular & Cellular Biology
Molecular/cellular biology and gene therapy of inherited and environmental diseases
England, Sarah, PhD Professor Molecular Physiology & Biophysics
Molecular & Cellular Biology
Molecular mechanisms regulating potassium channel function during pregnancy and vascular dysfunction
Feiss, Michael, PhD Professor Microbiology
Genetics
Molecular & Cellular Biology
Virus DNA packaging: mechanistic studies using phage lambda
Fritzsch, Bernd, PhD Professor (Chair) Biology
Otolaryngology
The molecular basis of ear neurosensory development with the aim to improve longevity of sensory neurons and ultimately restore hearing.
Fuentes, Ernesto, PhD Assistant Professor Biochemistry
Center for Biocatalysis & Bioprocessing
Training Program in the Pharmacological Sciences
Molecular & Cellular Biology
Molecular mechanisms governing specific signal transduction pathways
Gardinier, Minnetta, PhD Professor Pharmacology
Oligodendroglial cell biology and CNS myelination
Geyer, Pamela, PhD Professor Biochemistry
Genetics
Molecular & Cellular Biology
Role of chromosome structure and organization on gene expression in Drosophila
Giangrande, Paloma, PhD Assistant Professor Internal Medicine
Molecular & Cellular Biology
Developing RNA-based therapeutics to modulate cellular pathways underlying pathological cell proliferation in the setting of cancer and cardiovascular disease.
Goswami, Prabhat, PhD Associate Professor Radiation Oncology
Free Radical & Radiation Biology
Human Toxicology
Molecular & Cellular Biology
Intracellular Redox Environment and the Mammalian Cell Cycle
Green, Steven, PhD Professor Biology
Otolaryngology
Molecular & Cellular Biology
Neuroscience
Intracellular signaling: signal transduction for neurotrophic stimuli
Habelhah, Hasem, PhD Assistant Professor Pathology
Molecular & Cellular Biology
The role of TRAF2 phosphorylation in NF-?B activation and cancer cell resistance to apoptosis
Heusel, Jonathan, MD/PhD Assistant Professor Pathology
Immunology
Molecular parameters of natural killer (NK) cell activation in the settings of viral infection, cancer, and allogeneic hematopoietic stem cell transplantation
Hohl, Raymond, MD/PhD Professor Internal Medicine
Pharmacology
Molecular & Cellular Biology
Role of Isoprene Compounds in Cell Proliferation and Differentiation
Horswill, Alexander, PhD Assistant Professor Microbiology
Bacterial cell-to-cell communication using autoinducing peptides
Houston, Douglas, PhD Assistant Professor Biology
Genetics
Neuroscience
Maternal transcription factor and signalling pathways in vertebrate development
Ianzini, Fiorenza, PhD Assistant Professor Pathology
Radiation Oncology and Biomedical Engineering
Free Radical & Radiation Biology
Molecular Regulators of Cell Cycle Progression and Radiation- and Anticancer Drug-Induced Mitotic Catastrophe in Cancer Promotion and Progression
Janz, Siegfried, MD Professor Pathology
Immunology
Mouse models of human B cell and plasma cell neoplasms
Jones, Bradley, PhD Associate Professor Microbiology
Genetics
Bacteria-host cell interactions of Salmonella pathogenesis; Francisella pathogenesis
Khademi, Shahram, PharmD/PhD Assistant Professor Biochemistry
Molecular Physiology & Biophysics
Structure and function of membrane proteins using X-ray crystallography techniques
Kitamoto, Toshihiro, PhD Assistant Professor Anesthesia
Neurology
Genetics
Neuroscience
Genetics of complex behavior
Klingelhutz, Al, PhD Associate Professor Microbiology
Free Radical & Radiation Biology
Genetics
Molecular & Cellular Biology
Mechanisms of cellular immortalization and transformation by human papillomavirus
Kohen, Amnon, PhD Associate Professor Chemistry
Molecular & Cellular Biology
The role of protein dynamics and quantum mechanical effects in enzyme catalyzed hydrogen transfer and the mechanism of dinitrogen reduction by nitrogenases
Kuwana, Tomomi, PhD Assistant Professor Pathology
Molecular & Cellular Biology
Mitochondrial regulation of apoptosis
Legge, Kevin, PhD Assistant Professor Pathology
Immunology
Dendritic Cell Immunobiology and Pulmonary Immunity
Lentz, Steven, MD/PhD Professor Internal Medicine
Molecular & Cellular Biology
Vascular Cell Biology and Regulation of Hemostasis
Levasseur, Dana, PhD Assistant Professor Internal Medicine
Molecular & Cellular Biology
Transcriptional and epigenetic regulation of embryonic stem cell function and pluripotent stem cell biology
Lidral, Andrew, PhD/DDS Professor Orthodontics
Genetics
Molecular & Cellular Biology
Craniofacial developmental genetics
Lin, Jim (Chung-Jung), PhD Professor Biology
Genetics
Molecular & Cellular Biology
Structure and function of protein components of the cytoskeleton; molecular mechanisms of cardiac morphogenesis
Logsdon, John, PhD Associate Professor Biology
Genetics
Molecular & Cellular Biology
Evolutionary Molecular Genetics/Genomics: Origins and Evolution of Meiosis, Lateral Gene Transfer, Phylo-informatics
Maury, Wendy, PhD Associate Professor Microbiology
Molecular & Cellular Biology
Regulation of lentiviral cell tropism
McCaffrey, Anton, PhD Assistant Professor Internal Medicine
Genetics
Molecular & Cellular Biology
Role of RNA in human disease and the development of nucleic acid based therapeutics
McCarter, Linda, PhD Professor Microbiology
Surface sensing, signal transduction, biofilm formation, and regulation of gene expression and differentiation in bacteria
McGowan, Stephen, MD Professor Internal Medicine
Molecular & Cellular Biology
Connective tissue biochemistry in the lung
Meier, Jeffrey, MD Associate Professor Internal Medicine
Molecular & Cellular Biology
Viral pathogenesis at the molecular level
Menninger, John, PhD Professor Biology
Genetics
Molecular & Cellular Biology
Accuracy of Translation; Cellular Aging; mRNA/Ribosome co-evolution
Moye-Rowley, Scott, PhD Professor Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Transcriptional control of oxidative stress tolerance; eukaryotic multidrug resistance
Murray, Jeffrey, MD Professor Pediatrics
Biology
Epidemiology
Genetics
Molecular & Cellular Biology
Studies of human gene-environment interactions
Nagy, Peter, MD/PhD Assistant Professor Pathology
Biochemistry
Genetics
Histone methylation
Price, David, PhD Professor Biochemistry
Molecular & Cellular Biology
Eucaryotic gene regulation elongation control of RNA polymerase II
Quelle, Dawn, PhD Associate Professor Pharmacology
Molecular & Cellular Biology
Signaling pathways activated by the ARF & p53 tumor suppressors; molecular control of growth
Quelle, Frederick, PhD Associate Professor Pharmacology
Immunology
Cytokine receptor signal transduction mechanisms regulating cell growth and survival
Roller, Richard, PhD Professor Microbiology
Molecular & Cellular Biology
Function of herpes simplex virus membrane proteins in virus entry, exit from the cell and apoptosis regulation
Rothman, Paul, MD Professor (Head) Internal Medicine
Microbiology
Molecular Physiology & Biophysics
Immunology
Regulation of Cytokine Signaling
Rubenstein, Peter, PhD Professor Biochemistry
Internal Medicine
Molecular & Cellular Biology
Biochemical and biophysical basis of actin function; role of actin in maintenance of yeast mitochondrial function
Russo, Andrew, PhD Professor Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Control of neuronal gene expression
Rutkowski, Tom, PhD Assistant Professor Anatomy & Cell Biology
Molecular & Cellular Biology
Mechanisms of adaptation to chronic cellular stresses in physiology and disease
Sheff, David, MD/PhD Assistant Professor Pharmacology
Molecular & Cellular Biology
Intracellular Membrane Traffic and Receptor Sorting in the Endosomal System
Shih, Ming-Che, PhD Professor Biology
Gene regulation of plant metabolism
Sigmund, Curt, PhD Professor Internal Medicine
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Molecular genetics and molecular biology of the renin-angiotensin system and hypertension. Cardiovascular biology.
Soll, David, PhD Professor Biology
Molecular Pathology and Cell Motility
Stamnes, Mark, PhD Associate Professor Molecular Physiology & Biophysics
Molecular & Cellular Biology
Molecular mechanisms of intracellular protein transport and sorting in the mammalian Golgi apparatus
Stauffer, George, PhD Professor Microbiology
Mechanisms of bacterial gene transcription
Stoltzfus, C. Martin, PhD Professor Microbiology
Molecular & Cellular Biology
HIV RNA splicing regulation
Stone, Edwin, MD/PhD Professor Ophthalmology & Visual Sciences
Genetics
Molecular genetics of inherited eye diseases
Strack, Stefan, PhD Associate Professor Pharmacology
Molecular & Cellular Biology
Neuroscience
Protein phosphatases in neuronal signal transduction and disease
Sutterwala, Fayyaz, MD/PhD Assistant Professor Internal Medicine
Immunology
Molecular & Cellular Biology
Biology of the NOD-like receptor family in infection and inflammation.
Tan, Kai, PhD Assistant Professor Internal Medicine
Biomedical Engineering
Genetics
Understanding gene regulatory networks and molecular pathways in human diseases
Thomas, Christie, MD Professor Internal Medicine
Molecular & Cellular Biology
Organization and regulation of the epithelial sodium channel, sgk1 and Nedd4-2
Tootle, Tina, PhD Assistant Professor Anatomy & Cell Biology
The Tootle lab studies the molecular mechanisms by which prostaglandins mediate actin dynamics and cell migration during Drosophila oogenesis.
Turek, Lubomir, MD Professor Pathology
Molecular & Cellular Biology
Molecular biology and epidemiology of human papillomavirus in infection and cancer
Wallrath, Lori, PhD Professor Biochemistry
Genetics
Molecular & Cellular Biology
The role of chromatin proteins in disease
Washington, M. Todd, PhD Associate Professor Biochemistry
Molecular & Cellular Biology
Understanding the mechanisms of DNA polymerases involved in both mutagenic and error-free replication of DNA damage at the thermodynamic, kinetic, and structural level
Weeks, Daniel, PhD Professor Biochemistry
Molecular & Cellular Biology
Molecular mechanisms of early embryogenesis, cardiogenesis, and the development of novel oligonucleotide based stratagies to investigate control of development
Weiss, David, PhD Associate Professor Microbiology
Genetics
Cell division and protein localization in bacteria
Welsh, Michael, MD Professor Internal Medicine
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Biology of cystic fibrosis; structure and fuction of ion channels; pathogenesis of lung disease
Wilson, Mary, MD Professor Internal Medicine
Microbiology
Epidemiology
Genetics
Immunology
Molecular & Cellular Biology
Immunobiology, genetics, and molecular biology of visceral leishmaniasis in murine and human hosts
Wold, Marc, PhD Professor Biochemistry
Molecular & Cellular Biology
Molecular mechanisms of eukaryotic chromosomal DNA replication
Xing, Yi, PhD Assistant Professor Internal Medicine
Biomedical Engineering
Genetics
Bioinformatics of RNA splicing and alternative splicing, comparative genomics, and microarray data analysis.
Yeaman, Charles, PhD Associate Professor Anatomy & Cell Biology
Molecular & Cellular Biology
Cell mechanisms involved in development and maintenance of epithelial cell polarity
Zabner, Joseph, MD Professor Internal Medicine
Molecular & Cellular Biology
Gene transfer to human airway epithelia in particular developing gene therapy for cystic fibrosis

 
 

 

Biosciences Program
The University of Iowa
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Iowa City, IA 52242-1181

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