Biosciences Program Faculty performing Cardiovascular Biology research

A uniquely attractive feature of cardiovascular research at The University of Iowa is the close working relationship and cooperation between members of the basic science departments and the members of the clinical departments, particularly the Departments of Anatomy & Cell Biology, Internal Medicine, Pharmacology, Physiology & Biophysics and Pediatrics.

The UI Cardiovascular Center was established in 1975 by the Dean of the College of Medicine under the direction of Dr. Francois Abboud. The purpose of the Center was to coordinate the cardiovascular programs of the College into a more cohesive unit to permit the University to 1) utilize its cardiovascular resources optimally, 2) intensify, expand and integrate basic and clinical research programs in areas related to cardiovascular research, and 3) evaluate the role of new measures for prevention, diagnosis and treatment of cardiovascular disease.

Another important element in the success of this Cardiovascular Center has been the availability of a critical mass of basic scientists and clinical investigators who have full-time faculty appointments with tenure at the UI. This represents a major commitment of UI and state resources to cardiovascular programs which have been a significant element in its stability and success.

Name

Rank

Department/
Program
Research Description
Abboud, Francois, MD Professor Internal Medicine
Molecular Physiology & Biophysics
Neuroscience
Neural regulation of the circulation in normal and pathologic states such as hypertension and heart failure
Anderson, Mark, MD/PhD Professor Internal Medicine
Molecular Physiology & Biophysics
Cellular signaling and ionic mechanisms that cause heart failure and sudden cardiac death
Benson, Christopher, MD Associate Professor Internal Medicine
Neuroscience
Study of molecular mechanisms of sensory transduction
Bhalla, Ramesh, DVM/PhD Professor Anatomy & Cell Biology
Molecular mechanisms of cardiovascular function in health and disease
Campbell, Kevin, PhD Professor (Head) Molecular Physiology & Biophysics
Neurology
Cell biological studies of muscular dystrophy
Chapleau, Mark, PhD Professor Internal Medicine
Molecular Physiology & Biophysics
Neuroscience
Neural mechanisms of cardiovascular regulation. Baroreflex function in health and disease
Choudhury, Amit, PhD Assistant Professor Anatomy & Cell Biology
Molecular mechanisms of sorting and trafficking of lipids and proteins associated with “membrane rafts” in normal and pathophysiological angiogenesis
England, Sarah, PhD Professor Molecular Physiology & Biophysics
Molecular & Cellular Biology
Molecular mechanisms regulating potassium channel function during pregnancy and vascular dysfunction
Faraci, Frank, PhD Professor Internal Medicine
Pharmacology
Neuroscience
Vascular biology and mechanisms of vascular dysfunction in disease states
Giangrande, Paloma, PhD Assistant Professor Internal Medicine
Molecular & Cellular Biology
Developing RNA-based therapeutics to modulate cellular pathways underlying pathological cell proliferation in the setting of cancer and cardiovascular disease.
Heistad, Donald, MD Professor Internal Medicine
Pharmacology
Cerebral circulation and atherosclerosis; gene transfer and therapy
Johnson, Alan Kim, PhD Professor Psychology
Pharmacology
Integrative Physiology
Neuroscience
Neural Control of Body Fluid Balance and Cardiovascular Homeostasis
Kawai, Masataka, PhD Professor Anatomy & Cell Biology
Molecular mechanism of contraction in thin filament-reconstituted myocardium
Kwitek, Anne, PhD Associate Professor Internal Medicine
Molecular Physiology and Biophysics
Genetics
Genetics of complex disease (hypertension, diabetes and obesity)
Lamping, Kathryn, PhD Associate Professor Internal Medicine
Pharmacology
Effects of diabetes and sex differences in vascular reactivity
Lentz, Steven, MD/PhD Professor Internal Medicine
Molecular & Cellular Biology
Vascular Cell Biology and Regulation of Hemostasis
Lin, Jim (Chung-Jung), PhD Professor Biology
Genetics
Molecular & Cellular Biology
Structure and function of protein components of the cytoskeleton; molecular mechanisms of cardiac morphogenesis
Meier, Jeffrey, MD Associate Professor Internal Medicine
Molecular & Cellular Biology
Viral pathogenesis at the molecular level
Mohler, Peter, PhD Associate Professor Internal Medicine
Molecular Physiology and Biophysics
Ankyrin-based pathways for targeting and restriction of ion channels/transporters to specialized membrane domains.
Moser, David, PhD Associate Professor Psychiatry
Neuroscience
Current ongoing studies involve cognitive functioning, psychiatric symptoms, and neuroimaging in elderly patients with vascular disease
Nagy, Peter, MD/PhD Assistant Professor Pathology
Biochemistry
Genetics
Histone methylation
Russo, Andrew, PhD Professor Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Control of neuronal gene expression
Shibata, Erwin, PhD Associate Professor Molecular Physiology & Biophysics
Mechanism of direct Gsalpha modulation of cardiac ion channels
Sigmund, Curt, PhD Professor Internal Medicine
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Molecular genetics and molecular biology of the renin-angiotensin system and hypertension. Cardiovascular biology.
Slusarski, Diane, PhD Associate Professor Biology
Genetics
Signal transduction mechanisms in development and disease
Song, Long-Sheng, MD Assistant Professor Internal Medicine
Neuroscience
We focus on local Ca2+ signaling in health and diseases with state of the art confocal Ca2+ imaging techniques and genetic mouse models.
Talman, William, MD Professor Neurology
Neuroscience
Cardiovascular regulation by the CNS
Tomanek, Robert, PhD Professor Anatomy & Cell Biology
Understanding growth (vasculogenesis and angiogenesis) and adaptations of coronary vessels in health and disease
Weeks, Daniel, PhD Professor Biochemistry
Molecular & Cellular Biology
Molecular mechanisms of early embryogenesis, cardiogenesis, and the development of novel oligonucleotide based stratagies to investigate control of development
Zavazava, Nicholas, MD/PhD Professor Internal Medicine
Immunology
Mechanisms and molecular basis of embryonic stem cell differentiation

 
 

 

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