Biosciences Program Faculty performing Biochemistry research

Biochemistry research at the University of Iowa includes laboratories in the Department of Biochemistry and other programs on campus.

The Department of Biochemistry at The University of Iowa offers research programs in a diverse array of fields. Topics of research interest include protein structure, membrane transport, signal transduction, transcriptional regulation, metabolism and cytoskeleton organization.

· Biochemistry
· Cell Biology
· Genetics
· Molecular Biology
· Molecular Biophysics

Name

Rank

Department/
Program
Research Description
Accardi, Alessio, PhD Assistant Professor Molecular Physiology & Biophysics
Structure and function of chloride channels and transporters. Their involvement in kidney and bone diseases.
Brenner, Charles, PhD Professor (Head) Biochemistry
Molecular & Cellular Biology
Tumor suppressor gene function and NAD metabolism
Chen, Songhai, MD/PhD Assistant Professor Pharmacology
G protein-dependent signaling mechanisms of leukocyte migration and tumor metastasis
Dagle, John, MD/PhD Associate Professor Pediatrics
Biochemistry
Antisense oligonucleotide and siRNA technology, early vertebrate development, and the genetics of prematurity
Davidson, Beverly, PhD Professor Internal Medicine
Neurology
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Molecular and cellular mechanisms of CNS dysfunction in metabolic diseases and gene transfer to the CNS
DeMali, Kris, PhD Assistant Professor Biochemistry
Molecular & Cellular Biology
Cellular mechanisms involved in assembly and maintenance of cell-cell adhesions by examining the function and regulation of proteins recruited to the cytoplasmic face of cadherins
Domann, Frederick, PhD Professor Radiation Oncology
Free Radical & Radiation Biology
Human Toxicology
Molecular & Cellular Biology
DNA methylation and oncogenes, Ras and Cancer, Redox regulation of AP-2
Donelson, John, PhD Professor Biochemistry
Molecular biology of parasites that cause tropical diseases
Duffel, Michael, PhD Professor (Associate Dean) Medicinal & Natural Products Chemistry
Human Toxicology
Biochemistry of enzymes involved in mammalian conversion of drugs to reactive metabolites that mediate toxic and therapeutic effects
Elcock, Adrian, PhD Associate Professor Biochemistry
Understanding macromolecular interactions through the use of computer simulations and bioinformatics techniques: structure and function of multi-enzyme complexes; protein-protein association events
Engelhardt, John, PhD Professor (Head) Anatomy & Cell Biology
Internal Medicine
Free Radical & Radiation Biology
Molecular & Cellular Biology
Molecular/cellular biology and gene therapy of inherited and environmental diseases
Fisher, Rory, PhD Professor Pharmacology
Molecular & Cellular Biology
Siganal transduction of G protein-coupled receptors and RGS proteins
Fuentes, Ernesto, PhD Assistant Professor Biochemistry
Center for Biocatalysis & Bioprocessing
Training Program in the Pharmacological Sciences
Molecular & Cellular Biology
Molecular mechanisms governing specific signal transduction pathways
Geyer, Pamela, PhD Professor Biochemistry
Genetics
Molecular & Cellular Biology
Role of chromosome structure and organization on gene expression in Drosophila
Giudice, George, PhD Professor Dermatology
Biochemistry
Immunology
Molecular and cell biology of the dermal-epidermal junction
Horswill, Alexander, PhD Assistant Professor Microbiology
Bacterial cell-to-cell communication using autoinducing peptides
Houtman, Jon, PhD Assistant Professor Microbiology
Immunology
Molecular & Cellular Biology
Role of Adaptor Proteins in T Cell Activation
Khademi, Shahram, PharmD/PhD Assistant Professor Biochemistry
Molecular Physiology & Biophysics
Structure and function of membrane proteins using X-ray crystallography techniques
Kirby, John, PhD Associate Professor Microbiology
Genetics
Signal transduction in bacteria
Kohen, Amnon, PhD Associate Professor Chemistry
Molecular & Cellular Biology
The role of protein dynamics and quantum mechanical effects in enzyme catalyzed hydrogen transfer and the mechanism of dinitrogen reduction by nitrogenases
Koland, John, PhD Associate Professor Pharmacology
Molecular & Cellular Biology
Signal Transduction by Growth Factor Receptor / Protein Tyrosine Kinases
Kuwana, Tomomi, PhD Assistant Professor Pathology
Molecular & Cellular Biology
Mitochondrial regulation of apoptosis
Lee, Gloria, PhD Associate Professor Internal Medicine
Molecular & Cellular Biology
Neuroscience
Neuronal cytoskeleton, signal transduction, and neurodegenerative diseases
Levasseur, Dana, PhD Assistant Professor Internal Medicine
Molecular & Cellular Biology
Transcriptional and epigenetic regulation of embryonic stem cell function and pluripotent stem cell biology
Menninger, John, PhD Professor Biology
Genetics
Molecular & Cellular Biology
Accuracy of Translation; Cellular Aging; mRNA/Ribosome co-evolution
Nagy, Peter, MD/PhD Assistant Professor Pathology
Biochemistry
Genetics
Histone methylation
Nauseef, William, MD Professor Internal Medicine
Microbiology
Immunology
Molecular & Cellular Biology
Human polymorphonuclear neutrophil metabolism and function
Plapp, Bryce, PhD Professor Biochemistry
Mechanisms of alcohol dehydrogenases; protein chemistry, structure, and function; enzyme engineering by directed mutagenesis; regulation of alcohol metabolism
Price, David, PhD Professor Biochemistry
Molecular & Cellular Biology
Eucaryotic gene regulation elongation control of RNA polymerase II
Rubenstein, Peter, PhD Professor Biochemistry
Internal Medicine
Molecular & Cellular Biology
Biochemical and biophysical basis of actin function; role of actin in maintenance of yeast mitochondrial function
Shea, Madeline, PhD Professor Biochemistry
Regulatory protein interactions in signal transduction, allosteric mechanism of cooperative calcium binding to calmodulin
Sheff, David, MD/PhD Assistant Professor Pharmacology
Molecular & Cellular Biology
Intracellular Membrane Traffic and Receptor Sorting in the Endosomal System
Spitz, Douglas, PhD Professor Radiation Oncology
Free Radical & Radiation Biology
Human Toxicology
Redox regulation of signal transduction and gene expression, oxidative stress responses, mitochondrial free radical production, and aging.
Stamnes, Mark, PhD Associate Professor Molecular Physiology & Biophysics
Molecular & Cellular Biology
Molecular mechanisms of intracellular protein transport and sorting in the mammalian Golgi apparatus
Strack, Stefan, PhD Associate Professor Pharmacology
Molecular & Cellular Biology
Neuroscience
Protein phosphatases in neuronal signal transduction and disease
Tan, Kai, PhD Assistant Professor Internal Medicine
Biomedical Engineering
Genetics
Understanding gene regulatory networks and molecular pathways in human diseases
Tootle, Tina, PhD Assistant Professor Anatomy & Cell Biology
The Tootle lab studies the molecular mechanisms by which prostaglandins mediate actin dynamics and cell migration during Drosophila oogenesis.
Wallrath, Lori, PhD Professor Biochemistry
Genetics
Molecular & Cellular Biology
The role of chromatin proteins in disease
Washington, M. Todd, PhD Associate Professor Biochemistry
Molecular & Cellular Biology
Understanding the mechanisms of DNA polymerases involved in both mutagenic and error-free replication of DNA damage at the thermodynamic, kinetic, and structural level
Weeks, Daniel, PhD Professor Biochemistry
Molecular & Cellular Biology
Molecular mechanisms of early embryogenesis, cardiogenesis, and the development of novel oligonucleotide based stratagies to investigate control of development
Weiss, Jerrold, PhD Professor Internal Medicine
Microbiology
Human Toxicology
Immunology
Innate mammalian antibacterial defense mechanisms
Wold, Marc, PhD Professor Biochemistry
Molecular & Cellular Biology
Molecular mechanisms of eukaryotic chromosomal DNA replication
Yeaman, Charles, PhD Associate Professor Anatomy & Cell Biology
Molecular & Cellular Biology
Cell mechanisms involved in development and maintenance of epithelial cell polarity

 
 

 

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