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Biosciences Program Faculty performing Molecular Medicine research
Students interested in Molecular Medicine at the University of Iowa benefit from integrated training in human functional anatomy and cell biology as a foundation for careers in research concerning the molecular mechanisms of human diseases.
Training reflects a global approach toward understanding the human body, organ function, and disease pathophysiology, while providing the molecular training essential for the development of successful careers in research. Through broad-based training, students develop a comprehensive view of human disease pathophysiology and molecular medicine.
Nearly all-common diseases are complex in etiology. At the University of Iowa researchers in the Biosciences are using interdisciplinary approaches to discover the causes of several complex disorders and to develop treatments for them.
Some of the complex diseases being studied at the University of Iowa include:
Alzheimer's Disease
Autism
Battens Disease
Cancer
Cleft Lip and Palate
Cystic Fibrosis
Heart Disease
Huntington's Disease
Inherited Hearing Impairments
Macular Degeneration
Muscular Dystrophy
Obesity
Parkinson's Disease |
| Name |
Rank |
Department/
Program |
Research
Description |
|
Anderson, Mark, MD/PhD |
Professor |
Internal Medicine
Molecular Physiology & Biophysics
|
Cellular signaling and ionic mechanisms that cause heart failure and sudden cardiac death |
|
Anderson, Michael G., PhD |
Assistant Professor |
Molecular Physiology & Biophysics
Ophthalmology & Visual Sciences
Genetics
Neuroscience
|
Understanding fundamental physiological properties of the eye and the pathophysiological mechanisms underlying a variety of complex eye diseases |
|
Apicella, Michael, MD |
Professor (Head) |
Microbiology
Immunology
Molecular & Cellular Biology
|
Understanding of the molecular basis of the human immune response to Neisseria and Haemophilus to improve vaccine technology. |
|
Arnold, Mark, PhD |
Professor |
Chemistry
|
Development of chemical sensors for neuroactive compounds |
|
Bickenbach, Jackie, PhD |
Professor |
Anatomy & Cell Biology
Dermatology
Pathology
Genetics
Molecular & Cellular Biology
|
Activation of embryonic transcription factors in epidermal stem cells and the dynamics of dedifferentiation in cancer biology and wound healing |
|
Bishop, Gail, PhD |
Professor |
Microbiology
Internal Medicine
Immunology
Molecular & Cellular Biology
|
Molecular mechanisms of lymphocyte activation; role in normal immunity, autoimmunity, and lymphoma. |
|
Brenner, Charles, PhD |
Professor (Head) |
Biochemistry
Molecular & Cellular Biology
|
Tumor suppressor gene function and NAD metabolism |
|
Campbell, Kevin, PhD |
Professor (Head) |
Molecular Physiology & Biophysics
Neurology
|
Cell biological studies of
muscular dystrophy |
|
Choudhury, Amit, PhD |
Assistant Professor |
Anatomy & Cell Biology
|
Molecular mechanisms of sorting and trafficking of lipids and proteins associated with “membrane rafts” in normal and pathophysiological angiogenesis |
|
Cohen, Michael, MD |
Professor |
Pathology
Urology
Epidemiology
Molecular & Cellular Biology
|
Receptor-ligand-mediated cell death in prostate cancer |
|
Dagle, John, MD/PhD |
Associate Professor |
Pediatrics
Biochemistry
|
Antisense oligonucleotide and siRNA technology, early vertebrate development, and the genetics of prematurity |
|
Davidson, Beverly, PhD |
Professor |
Internal Medicine
Neurology
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
|
Molecular and cellular mechanisms of CNS dysfunction in metabolic diseases and gene transfer to the CNS |
|
Domann, Frederick, PhD |
Professor |
Radiation Oncology
Free Radical & Radiation Biology
Human Toxicology
Molecular & Cellular Biology
|
DNA methylation and oncogenes, Ras and Cancer, Redox regulation of AP-2 |
|
Dupuy, Adam, PhD |
Assistant Professor |
Anatomy & Cell Biology
Genetics
Molecular & Cellular Biology
|
Developing new mouse models of human cancer using the Sleeping Beauty transposon system |
|
Engelhardt, John, PhD |
Professor (Head) |
Anatomy & Cell Biology
Internal Medicine
Free Radical & Radiation Biology
Molecular & Cellular Biology
|
Molecular/cellular biology and gene therapy of inherited and environmental diseases |
|
Faraci, Frank, PhD |
Professor |
Internal Medicine
Pharmacology
Neuroscience
|
Vascular biology and mechanisms of vascular dysfunction in disease states |
|
Geyer, Pamela, PhD |
Professor |
Biochemistry
Genetics
Molecular & Cellular Biology
|
Role of chromosome structure and organization on gene expression in Drosophila |
|
Giangrande, Paloma, PhD |
Assistant Professor |
Internal Medicine
Molecular & Cellular Biology
|
Developing RNA-based therapeutics to modulate cellular pathways underlying pathological cell proliferation in the setting of cancer and cardiovascular disease. |
|
Goel, Apollina, PhD |
Assistant Professor |
Radiation Oncology
Free Radical & Radiation Biology
|
Chemo-radiotherapy for hematological malignancies.
Understanding and circumventing therapy-resistance in multiple myeloma. |
|
Heistad, Donald, MD |
Professor |
Internal Medicine
Pharmacology
|
Cerebral circulation and atherosclerosis; gene transfer and therapy |
|
Heusel, Jonathan, MD/PhD |
Assistant Professor |
Pathology
Immunology
|
Molecular parameters of natural killer (NK) cell activation in the settings of viral infection, cancer, and allogeneic hematopoietic stem cell transplantation |
|
Hohl, Raymond, MD/PhD |
Professor |
Internal Medicine
Pharmacology
Molecular & Cellular Biology
|
Role of Isoprene Compounds in Cell Proliferation and Differentiation |
|
Lee, Gloria, PhD |
Associate Professor |
Internal Medicine
Molecular & Cellular Biology
Neuroscience
|
Neuronal cytoskeleton, signal transduction, and neurodegenerative diseases |
|
Lentz, Steven, MD/PhD |
Professor |
Internal Medicine
Molecular & Cellular Biology
|
Vascular Cell Biology and Regulation of Hemostasis |
|
Leslie, Kimberly, MD |
Professor (Head) |
Obstetrics & Gynecology
Molecular & Cellular Biology
|
The molecular biology of estrogen and progesterone receptors, the effects of antiestrogens in the female reproductive tract, endometrial cancer, interactions between epidermal growth factor and hormone receptors. |
|
Levasseur, Dana, PhD |
Assistant Professor |
Internal Medicine
Molecular & Cellular Biology
|
Transcriptional and epigenetic regulation of embryonic stem cell function and pluripotent stem cell biology |
|
McCaffrey, Anton, PhD |
Assistant Professor |
Internal Medicine
Genetics
Molecular & Cellular Biology
|
Role of RNA in human disease and the development of nucleic acid based therapeutics |
|
McCray, Paul, MD |
Professor |
Pediatrics
Microbiology
Genetics
Human Toxicology
|
Gene Therapy for Genetic Diseases; Pathogenesis and Treatment of Cystic Fibrosis; Identification and Characterization of Host Defense Peptides and Proteins |
|
Morita, Craig T., MD/PhD |
Associate Professor |
Internal Medicine
Immunology
Molecular & Cellular Biology
|
Nonpeptide antigen recognition by gamma-delta T cells |
|
Murray, Jeffrey, MD |
Professor |
Pediatrics
Biology
Epidemiology
Genetics
Molecular & Cellular Biology
|
Studies of human gene-environment interactions |
|
Nagy, Peter, MD/PhD |
Assistant Professor |
Pathology
Biochemistry
Genetics
|
Histone methylation |
|
O'Dorisio, Sue, MD/PhD |
Professor |
Pediatrics
Neuroscience
|
Molecularly targeted cancer imaging and therapy. Neuropeptides that modulate neurotransmission and provide neuroprotection. |
|
Rothman, Paul, MD |
Professor (Head) |
Internal Medicine
Microbiology
Molecular Physiology & Biophysics
Immunology
|
Regulation of Cytokine Signaling |
|
Russo, Andrew, PhD |
Professor |
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
|
Control of neuronal gene expression |
|
Sheff, David, MD/PhD |
Assistant Professor |
Pharmacology
Molecular & Cellular Biology
|
Intracellular Membrane Traffic and Receptor Sorting in the Endosomal System |
|
Sigmund, Curt, PhD |
Professor |
Internal Medicine
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
|
Molecular genetics and molecular biology of the renin-angiotensin system and hypertension. Cardiovascular biology. |
|
Soll, David, PhD |
Professor |
Biology
|
Molecular Pathology and Cell Motility |
|
Song, Long-Sheng, MD |
Assistant Professor |
Internal Medicine
Neuroscience
|
We focus on local Ca2+ signaling in health and diseases with state of the art confocal Ca2+ imaging techniques and genetic mouse models. |
|
Strack, Stefan, PhD |
Associate Professor |
Pharmacology
Molecular & Cellular Biology
Neuroscience
|
Protein phosphatases in neuronal signal transduction and disease |
|
Thomas, Christie, MD |
Professor |
Internal Medicine
Molecular & Cellular Biology
|
Organization and regulation of the epithelial sodium channel, sgk1 and Nedd4-2 |
|
Washington, M. Todd, PhD |
Associate Professor |
Biochemistry
Molecular & Cellular Biology
|
Understanding the mechanisms of DNA polymerases involved in both mutagenic and error-free replication of DNA damage at the thermodynamic, kinetic, and structural level |
|
Welsh, Michael, MD |
Professor |
Internal Medicine
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
|
Biology of cystic fibrosis; structure and fuction of ion channels; pathogenesis of lung disease |
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