Biosciences Program Faculty performing Gene Regulation research

Cells respond to changes in their environment and to a host of developmental cues by regulating the expression of specific genes. The regulation of gene expression involves the combinatorial actions of multiple factors from chromatin structure to protein modification. Discovering the mechanisms that control gene regulation is one of the major goals of research at the University of Iowa.

Name

Rank

Department/
Program
Research Description
Abboud, Francois, MD Professor Internal Medicine
Molecular Physiology & Biophysics
Neuroscience
Neural regulation of the circulation in normal and pathologic states such as hypertension and heart failure
Bishop, Gail, PhD Professor Microbiology
Internal Medicine
Immunology
Molecular & Cellular Biology
Molecular mechanisms of lymphocyte activation; role in normal immunity, autoimmunity, and lymphoma.
Brenner, Charles, PhD Professor (Head) Biochemistry
Molecular & Cellular Biology
Tumor suppressor gene function and NAD metabolism
Cheng, Chi-Lien, PhD Associate Professor Biology
Genetics
Alternation of generations in land plants
Domann, Frederick, PhD Professor Radiation Oncology
Free Radical & Radiation Biology
Human Toxicology
Molecular & Cellular Biology
DNA methylation and oncogenes, Ras and Cancer, Redox regulation of AP-2
Donelson, John, PhD Professor Biochemistry
Molecular biology of parasites that cause tropical diseases
Ellermeier, Craig, PhD Assistant Professor Microbiology
Bacterial cell signaling
Engelhardt, John, PhD Professor (Head) Anatomy & Cell Biology
Internal Medicine
Free Radical & Radiation Biology
Molecular & Cellular Biology
Molecular/cellular biology and gene therapy of inherited and environmental diseases
Fassler, Jan, PhD Professor Biology
Genetics
Eukaryotic gene expression and signal transduction; characterization of two-component regulators in yeast
Fisher, Rory, PhD Professor Pharmacology
Molecular & Cellular Biology
Siganal transduction of G protein-coupled receptors and RGS proteins
Gardinier, Minnetta, PhD Professor Pharmacology
Oligodendroglial cell biology and CNS myelination
Geyer, Pamela, PhD Professor Biochemistry
Genetics
Molecular & Cellular Biology
Role of chromosome structure and organization on gene expression in Drosophila
Houston, Douglas, PhD Assistant Professor Biology
Genetics
Neuroscience
Maternal transcription factor and signalling pathways in vertebrate development
Jones, Bradley, PhD Associate Professor Microbiology
Genetics
Bacteria-host cell interactions of Salmonella pathogenesis; Francisella pathogenesis
Kirby, John, PhD Associate Professor Microbiology
Genetics
Signal transduction in bacteria
Kitamoto, Toshihiro, PhD Assistant Professor Anesthesia
Neurology
Genetics
Neuroscience
Genetics of complex behavior
Klingelhutz, Al, PhD Associate Professor Microbiology
Free Radical & Radiation Biology
Genetics
Molecular & Cellular Biology
Mechanisms of cellular immortalization and transformation by human papillomavirus
Leslie, Kimberly, MD Professor (Head) Obstetrics & Gynecology
Molecular & Cellular Biology
The molecular biology of estrogen and progesterone receptors, the effects of antiestrogens in the female reproductive tract, endometrial cancer, interactions between epidermal growth factor and hormone receptors.
Levasseur, Dana, PhD Assistant Professor Internal Medicine
Molecular & Cellular Biology
Transcriptional and epigenetic regulation of embryonic stem cell function and pluripotent stem cell biology
Lidral, Andrew, PhD/DDS Professor Orthodontics
Genetics
Molecular & Cellular Biology
Craniofacial developmental genetics
Logsdon, John, PhD Associate Professor Biology
Genetics
Molecular & Cellular Biology
Evolutionary Molecular Genetics/Genomics: Origins and Evolution of Meiosis, Lateral Gene Transfer, Phylo-informatics
McCarter, Linda, PhD Professor Microbiology
Surface sensing, signal transduction, biofilm formation, and regulation of gene expression and differentiation in bacteria
Meier, Jeffrey, MD Associate Professor Internal Medicine
Molecular & Cellular Biology
Viral pathogenesis at the molecular level
Moye-Rowley, Scott, PhD Professor Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Transcriptional control of oxidative stress tolerance; eukaryotic multidrug resistance
Nagy, Peter, MD/PhD Assistant Professor Pathology
Biochemistry
Genetics
Histone methylation
Price, David, PhD Professor Biochemistry
Molecular & Cellular Biology
Eucaryotic gene regulation elongation control of RNA polymerase II
Russo, Andrew, PhD Professor Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Control of neuronal gene expression
Rutkowski, Tom, PhD Assistant Professor Anatomy & Cell Biology
Molecular & Cellular Biology
Mechanisms of adaptation to chronic cellular stresses in physiology and disease
Shih, Ming-Che, PhD Professor Biology
Gene regulation of plant metabolism
Sigmund, Curt, PhD Professor Internal Medicine
Molecular Physiology & Biophysics
Genetics
Molecular & Cellular Biology
Neuroscience
Molecular genetics and molecular biology of the renin-angiotensin system and hypertension. Cardiovascular biology.
Soll, David, PhD Professor Biology
Molecular Pathology and Cell Motility
Stauffer, George, PhD Professor Microbiology
Mechanisms of bacterial gene transcription
Tan, Kai, PhD Assistant Professor Internal Medicine
Biomedical Engineering
Genetics
Understanding gene regulatory networks and molecular pathways in human diseases
Thomas, Christie, MD Professor Internal Medicine
Molecular & Cellular Biology
Organization and regulation of the epithelial sodium channel, sgk1 and Nedd4-2
Wallrath, Lori, PhD Professor Biochemistry
Genetics
Molecular & Cellular Biology
The role of chromatin proteins in disease
Weiss, David, PhD Associate Professor Microbiology
Genetics
Cell division and protein localization in bacteria
Wilson, Mary, MD Professor Internal Medicine
Microbiology
Epidemiology
Genetics
Immunology
Molecular & Cellular Biology
Immunobiology, genetics, and molecular biology of visceral leishmaniasis in murine and human hosts
Xing, Yi, PhD Assistant Professor Internal Medicine
Biomedical Engineering
Genetics
Bioinformatics of RNA splicing and alternative splicing, comparative genomics, and microarray data analysis.
Yahr, Timothy, PhD Associate Professor Microbiology
Role of the type III secretion system in Pseudomonas aeruginosa pathogenesis

 

 

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