Anatomy and Cell Biology

  • POSTDOCTORAL FELLOW
    Requisition #2634

    The Yeaman laboratory in the Department of Anatomy and Cell Biology at the University of Iowa is seeking a motivated, focused and skilled Postdoctoral Fellow. The Yeaman group is interested in identifying molecular mechanisms responsible for biogenesis of epithelial cell polarity (publications in Cell, Molecular Cell, Nature Cell Biology, J. Cell Biol., etc).  We study details of fundamental cellular processes, such as intercellular adhesion, cytoskeletal remodeling and membrane trafficking, that are at the foundation of tissue development and organogenesis.  Our focus is on the Exocyst, a multi-functional, allosterically regulated scaffold, and Ral GTPases, which regulate Exocyst functions by facilitating association or disassociation with additional proteins.  We utilize CRISPR/Cas9 gene editing, along with mouse models, 2D and 3D cell culture models, cutting edge cell imaging technologies and biochemical assays to understand how Exocyst protein assemblies function during cell growth and differentiation, motility and cell division.  We are performing focused structure-function studies in efforts to understand how specific mutations in genes encoding Exocyst and Ral proteins contribute to human diseases including cancers, diabetes and ciliopathies. The University of Iowa Carver College of Medicine is a highly ranked biomedical research institute. The Yeaman laboratory is located in a state-of-the-art facility that features a collaborative atmosphere to foster innovation.

    Qualifications: Interested candidates should have obtained a Ph.D. or M.D. degree with a strong background in molecular biology, cell biology and biochemistry. The ideal candidate will have proven talent to work independently with excellent interpersonal and communication skills.

    Desired: 

    • Solid knowledge in Cell and Molecular Biology and Biochemistry;
    • Extensive experience working with mammalian cell lines and primary cells (ideally polarized epithelial cultures grown on Transwells or in Matrigel);
    • Extensive experience with PCR, RT-PCR, molecular cloning, CRISPR/Cas9;
    • Experience with TIRF, super-resolution microscopy, confocal microscopy and electron microscopy;
    • Experience in mouse handling, genotyping, mouse surgeries, tissue dissection.

    To apply for this position visit our website at http://jobs.uiowa.edu; requisition #2634.  The University of Iowa is an Equal Opportunity/Affirmative Action Employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.  Applicants’ credentials are subject to verification.

     

    POSTDOCTORAL FELLOW
    Requisition #2617

    The Yang laboratory at the Fraternal Order of Eagles Diabetes Research Center at the University of Iowa is seeking a motivated, focused and skilled Postdoctoral Fellow. The Yang group is interested in identifying the molecular components of integration between organelle stress responses that are in play in obesity and diabetes at the cellular and organismic levels (publications in Science, Cell Metabolism and Diabetes). Genetic mouse models, cellular and in vivo metabolic analysis, cell culture, cell imaging and biochemistry assays will be used in the project. The University of Iowa Carver College of Medicine is a highly ranked biomedical research institute. The Yang laboratory is located in a state-of-the-art facility that features a collaborative atmosphere to foster innovation. 

    Qualifications: Interested candidates should have obtained a Ph.D. or M.D. degree with a strong background in mouse models, metabolism, molecular biology, cell biology and biochemistry. The ideal candidate will have proven talent to work independently with excellent interpersonal and communication skills.

    Desired: 

    • Solid knowledge in Cell biology, Biochemistry and metabolic diseases;
    • Extensive experience working with mammalian cell lines and primary cells (ideally primary hepatocyte culture);
    • Extensive experience with sub-clone, viral construction, as well as overexpression/suppression of target gene expression in mouse model;
    • Experience with flow cytometry, confocal microscopy and EM;
    • Profound experience in mouse metabolic profiling, animal handling, mouse surgeries, tissue dissection.

    To apply for this position visit our website at http://jobs.uiowa.edu; requisition #2617.  The University of Iowa is an Equal Opportunity/Affirmative Action Employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.  Applicants’ credentials are subject to verification.

     

    ASSOCIATE PROFESSOR
    Requisition  # 69573

     The Department of Anatomy and Cell Biology, University of Iowa, http://www.anatomy.uiowa.edu/, seeks an established independent investigator for a tenure-track faculty position at the Associate Professor level.  This is a 12-month appointment with a highly competitive start-up package, laboratory space, salary and benefits. Responsibilities will include maintaining a vibrant research program with significant extramural funding and participating actively in graduate teaching. 

    Current areas of research in the department include cell and developmental biology, vascular and lung biology, neurobiology, cancer, and stem cell biology. This is a joint recruitment with the Iowa Center for Molecular Auditory Neuroscience.  We seek candidates whose work will synergize with our current strengths in these areas.  The Department of Anatomy and Cell Biology is also the administrative home of the Center for Gene Therapy. http://genetherapy.genetics.uiowa.edu/ 

    Candidates must hold a Ph.D., M.D., or M.D./Ph.D.  Applicants should have extensive experience (>10 years) in the field of cellular auditory neuroscience and at least six years in faculty rank.  In particular, the applicant should have a strong track record of research and publishing utilizing electrophysiology of neurons in brain slices, synaptic recordings, imaging and microscopy, and the use of advanced viral vector technology for exogenous protein expression in neurons in vivo. The applicant should be recognized for outstanding scholarship with at least one senior-authored publication in a journal of impact factor >15, and should be PI on an NIH R01 grant.  Desired qualifications include the following:  The applicant’s research interests should closely align with the Dept. of Anatomy and Cell Biology, Iowa Center for Molecular Auditory Neuroscience, and the Neuroscience Institute. The applicant should have a strong record of mentoring graduate students, post-docs, and undergraduates. Viral experience with generating recombinant helper-dependent adenoviral vector systems is desirable. All applicants will have demonstrated experience working effectively in a diverse research environment. 

    To apply for this position, please visit http://jobs.uiowa.edu, requisition 69573.  Review of applicants will begin immediately.  Please direct questions to the search committee at mary-beckler@uiowa.edu. 

     

     The University of Iowa is an Equal Opportunity/Affirmative Action Employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran. Applicants’ credentials are subject to verification.