Anatomy and Cell Biology

  • Cell Biology

    Amit Choudhury, MSc, PhD

    • Mechanisms of sorting and trafficking of membrane rafts

    John F. Engelhardt, PhD 

    • Redox-mediated signal transduction pathways in disease
    • Receptor signaling and endosomal control of NADPH oxidases
    • Cell Biology of adeno-associated virus (AAV) transduction

    C. Andrew Frank, PhD

    • Synaptic transmission and muscle-to-nerve retrograde signaling in Drosophila

    Masataka Kawai, PhD

    • Molecular mechanisms of force generation in striated muscles
    • Reconstitution of the thin filament in cardiac muscles
    • Positive allosteric effect of tropomyosin on the actomysin interaction
    • Mechanisms of underlying hypertrophic cardiomyopathy (HCM)

    Fang Lin, MD, PhD

    • Involvement of G protein signaling in the migration of primordial germ cells (PGC)
    • Identification of G proteins and G protein-coupled receptors that regulate gastrulation

    Hank Qi, MD, PhD

    • Histone demethylases in transcriptional regulation towards cell differentiation and proliferation

    Tom Rutkowski, PhD

    • Mechanisms by which cells adapt or succumb to chronic protein misfolding stresses
    • Systems biology of the endoplasmic reticulum stress response—how integration of signals from distinct stress-sensing pathways brings about discrete changes in cellular physiology

    Tina Tootle, PhD

    • Mechanisms of prostaglandin-mediated cytoskeleton remodeling during Drosophila oogenesis
    • Border-cell migration as a model for understanding prostaglandin-mediated invasive cell migration

    Charles Yeaman, PhD

    • Cellular mechanisms involved in development and maintenance of epithelial-cell polarity
    • Roles of Ras-like GTPases and Exocyst in epithelial membrane trafficking
    • Functions of primary cilia in regulating epithelial-cell growth and differentiation