Nick Borcherding, BS
Graduate Student in the Department of Pathology Master Program
nicholas-borcherding@uiowa.edu
Contact information
1135 Medical Laboratories
500 Newton Rd
University of Iowa
Iowa City, IA 52242
Phone: 319-335-6832
Training
BS, Nutritional Science, Iowa State University, Ames, IA, 2009-2013
Research Interests
HER2+ breast cancer account for 25-30% of total invasive ductal breast carcinomas and is associated with a poor clinical prognosis. Elucidation and characterization of tumor-initiating cell populations in the Her2+ breast cancer represent a gateway into improving targeted-therapies. My current focus is cellular and genetic response to tyrosine kinase inhibitors and the interrelation of the NIK/IKKα module in drug resistance.
Publications
- Smazal A.*, Borcherding N.*, Anderegg A., Schalinske K., Rowling M. Dietary resistant starch prevents urinary excretion of 25-hydroxycholecalciferol and vitamin D-binding protein in type 1 diabetic rats. J Nutirition. 2013; In Press, *co-first author.
- Zhang W., Tan W., Wu X., Poustovoitov M., Strasner A., Li W., Borcherding N., Ghassemian M., and Michael Karin. A NIK-IKKα module expands ErbB2-induced tumor- initiating cells by stimulating nuclear export of p27/Kip1. 2013. Cancer Cell. In press.