Specimen:

Serum or Plasma

Collection Medium:

Alternate
Collection Media:

Lavender top tube (EDTA), Pink top tube (EDTA sprayed)

Minimum:

Preferred minimum: 3 mL serum from red top tube or EDTA plasma from 
lavender or pink top tube

Absolute minimum: 1 mL serum from red top tube or EDTA plasma from 
lavender or pink top tube

Rejection Criteria:

Gel separator tubes

Analytic Time:

7 working days

Reference Range:

<235.0 ng/mL

Interpretive Data:

Report Limit:  5.0 ng/mL
Therapeutic and toxic ranges have not been established. Peak 
concentrations are expected at 45 minutes post dose; steady state is 
generally attained within 2 days. Observed tiagabine concentrations in 
clinical trials (30-56 mg/day): <1 - 234 ng/mL. Measured tiagabine 
concentrations, post marketing (95% confidence interval): 0 - 440 
ng/mL. Note: The 95% confidence interval for tiagabine concentrations 
determined by reference laboratory will be updated periodically as more 
information becomes available.

Comments:

Draw specimen prior to dosing.

Methodology:

Liquid Chromatography/Tandem Mass Spectrometry

CPT Code:

82491