The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

Neisseria Meningitidis IgG Vaccine Response
Order Code: NMENIG
Order Form: A-1a Miscellaneous Request or IPR Req 		  Commercial "Mail-out" Laboratory
6240 RCP
356-3527 
Specimen
 
Serum
Collection Medium:
Red top tube 


Minimum:


0.5 mL serum


Delivery Instructions:


Submit specimen to laboratory as soon as possible after collection.


Analytic Time:


1 week


Reference Range:


Serogroup A: < 4.0 ug/mL
Serogroup C: < 5.0 ug/mL
Serogroup Y: < 4.0 ug/mL
Serogroup W-135: < 3.0 ug/mL


Comments:


This assay measures serum IgG antibodies recognizing polysaccharide 
antigens from the four Neisseria meningitidis serogroups included in 
the licensed meningococcal vaccine. The meningococcal vaccine response 
is best evaluated by testing pre-vaccination and post-vaccination 
samples in parallel. A two-fold or greater increase for at least two 
serogroups is expected when comparing post-vaccination to 
pre-vaccination results. N. meningitidis IgG levels peak approximately 
one month post-vaccination, but decline markedly by two years.


CPT Code:


86741 (x4)




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Updated: 04/25/2007

Note: The information contained in this handbook is  
            for use by personnel of University of Iowa Health Care. 
            No other use is implied or intended.