Specimen:

Plasma

Collection Medium:

Minimum:

1 mL plasma from a Special Z-GI preservative collection tube obtained 
from reference laboratory.  Mailouts has these tubes, call 356-8593.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Specimen
Instructions:

Patient should not be on any medications that affect hypertension, 
gastrointestinal functions, or pain relievers, if possible, for at 
least 48 hours prior to collection of specimen.

For tumor/tissue and various fluids (i.e. CSF, peritoneal, synovial, 
etc.) contact Commerical Mailouts (356-8593) for requirements and 
special handling.

Testing Schedule:

Varies

Analytic Time:

2 weeks

Reference Range:

Up to 40 pg/ml

Comments:

Contact Commercial Mailouts at 356-8593 to obtain collection tubes for 
this testing.  No other specimen collection container is acceptable by 
the reference laboratory.

Patients should be fasting for 10-12 hours prior to specimen 
collection.  Antacid medications or medications that affect intestinal 
motility should be discontinued, if possible, for at least 48 hours 
prior to collection.

Neurokinin A is a ten amino acid putative transmitter synthesized in 
the neurons it is present in.  Neurokinin A is a member of the family 
called Tachykinins which also include Neurokinin B, Substance P, 
Physalaemin, and Eledoisin.   Neurokinin A shares 6 of 10 peptide 
homologies with Neurokinin B even though they are produced by different 
genes.   Neurokinin A is also very similar in structure to Substance P 
and produces some of the same biological actions as Substance P.  
Neurokinin A is a potent bronchoconstrictor.  In the gut, Neurokinin A 
is produced by the intrinsic enteric nervous system.

Methodology:

Direct Radioimmunoassay

CPT Code:

83519