Specimen

Plasma or Serum

Collection Medium:

Alternate
Collection Media:

Lavender top tube (EDTA), Green top tube (Na Heparin), Pink top tube 
(EDTA sprayed)

Minimum:

Adult preferred minimum:  1.0 mL plasma or serum
Adult absolute minimum:  0.3 mL plasma or serum
Pediatric minimum:  0.1 mL plasma or serum

Rejection Criteria:

Severely lipemic, contaminated, heat-inactivated, or hemolyzed 
specimens.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Analytic Time:

1 week

Reference Range:

1.7 EV or less: Negative - No significant level of IgA antibody to H. 
pylori detected.

1.8-2.2 EV: Equivocal - Repeat testing in 10-14 days may be helpful.

2.3 EV or greater: Positive - IgA antibody to H. pylori detected, 
suggestive of active infection.

Test
Limitations:

Helicobacter pylori IgG and IgA antibody seroconversion occur together 
after 60 days. Samples which have a high titer of both IgG and IgA 
antibodies to H. pylori in symptomatic individuals may be considered to 
represent an active infection. However, a positive H. pylori IgA result 
can only suggest active infection and should be confirmed by bacterial 
isolation or other diagnostic testing.

Methodology:

Enzyme Immunoassay

CPT Code:

86677