Specimen

Whole blood

Collection Medium:

Minimum:

Adult minimum: 3 mL whole blood in lavender top (EDTA) tube

Delivery Instructions:

Room temperature for up to 24 hours, then refrigerate 
the whole blood if it is necessary to be held overnight, 
or weekends, or holidays.

Testing Schedule:

Weekly

Analytic Time:

14 days

Reference Range:

By report

Comments:

This test is available to symptomatic individuals only.  Predictive 
testing is not offered because this variant demonstrates reduced 
penetrance.  The LRRK2 G2019S variant is found in approximately 6% of 
families demonstrating autosomal dominant inheritance of PD and in 
approximately 1% of sporadic cases.

Test
Limitations:

Testing on smaller blood volumes than those requested will be 
attempted.  However, in some cases, small blood volumes may compromise 
the ability to perform testing.

Methodology:

Polymerase Chain Reaction: Amplification refractory mutation system 
(ARMS).

CPT Code:

83894, 83900, 83890, 83912