The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Hepatitis B Virus (HBV) Genotype, RFLP
Order Code: HBVGENO
Order Form: A-1a Miscellaneous Request or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Serum or Plasma
Collection Medium:
Red top tube
Alternate
Collection Media:
Lavender top tube (EDTA)
Minimum:
1 mL serum or plasma
Delivery Instructions:
Deliver to laboratory immediately after collection.
Analytic Time:
2 weeks
Reference Range:
By report
Test
Limitations:
Hepatitis B virus (HBV) is a well-kown agent of acute and chronic 
hepatitis, with approximately 300 million chronic carriers around the 
world. In the early 1970s, serotyping of HBV was introduced as a means 
of classification of varying HBV strains. Serotyping refers to the 
seroreactivity to three antigenic determinants residing in the HBV S 
antigen. The genomic basis for the seroreactivity has been elucidated 
by sequence analysis of the S gene, and it has been shown that the 
serotypes do not truly reflect phylogenetic relatedness within HBV. 
Genotyping methods based on sequence analysis of the HBV genome have 
recently been developed. This test can determine the following HBV 
genotypes: A1-A3, B1-B3, C1, C2, D1-D6, E, F1 and F2.
CPT Code:
83891, 83894, 83900, 83904(x4), 83912
 
See Additional Information:
Specimens Requiring Immediate Delivery

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Updated: 07/16/2008

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.