Specimen:

Whole Blood

Minimum:

7-15 mL amniotic fluid or cultured amniotic cells (2x10^6 cells 
minimum)

Analytic Time:

2 weeks

Reference Range:

By report

Comments:

Please print, complete, and submit the Molecular Diagnostics Test 
Requisition from the Blood Center of Wisconsin with the specimen and 
A-1a Miscellaneous Request.

Prenatal genotyping for Red Blood Cell (RBC) antigens used in studies 
for hemolytic disease of the newborn (HDN).  Prenatal testing can be 
performed on amniotic fluid.

Methodology:

Allel-specific Polymerase Chain Reaction (PCR)

CPT Code:

Possible CPT codes, based on antigen tested:
Duffy Antigen Genotyping (Fya and Fyb):83891, 83894, 83898(x4), 83912
Kidd Antigen Genotyping (Jka and Jkb):83891, 83894, 83898(x2), 83912
Kell and Cellano Antigen Genotyping (K1 and K2):83891, 83894, 
83898(x2), 83912
Rh C and Rh c Antigen Genotyping:83891, 83894, 83898(x2), 83912
Rh D Antigen Genotyping:83891, 83894, 83898(x2), 83912
Rh E and Rh e Antigen Genotyping:83891, 83894, 83898(x2), 83912
M Antigen Genotyping:83891, 83894, 83898, 83912

See also:
Genotyping, Red Cell Antigen, Parental, Whole Blood
RBC Antigen Testing Per Antigen, Blood