Specimen:

Serum or Plasma

Collection Medium:

Alternate
Collection Media:

Lavender top tube (EDTA), Pink top tube (EDTA sprayed), Green top tube 
(Na Heparin)

Minimum:

Preferred Minimum:  2 mL serum or plasma
Absolute Minimum: 0.8 mL serum or plasma
Pediatric Minimum:  0.8 mL serum or plasma

Rejection Criteria:

Separator tubes

Delivery Instructions:

Wrap specimen in aluminum foil to protect from light.

Analytic Time:

4 working days

Reference Range:

Therapeutic Range
Amiodarone: 1.0-3.0 ug/mL
Desethylamiodarone: Not established

Potential toxic level: > 3.0 ug/mL

Interpretive Data:

The therapeutic range of amiodarone is not presently well established. 
Toxic effects may begin above 3.0 ug/mL. The concentration of 
desethylamiodarone, a major metabolite, is also reported, but no 
therapeutic range is available.  At steady-state, the metabolite 
concentration is similar to the amiodarone concentration. This 
metabolite may be pharmacologically active, but the extent of activity 
is not known with certainty.

Comments:

Includes Desethylamiodarone.

Methodology:

High Performance Liquid Chromatography (HPLC)

CPT Code:

80299 (x2)

See Additional Information:
Commercial (Mailout) Critical Lab Values