Specimen

Serum

Collection Medium:

Minimum:

Adult minimum: 1 mL serum from red top tube
Pediatric minimum: 0.1 mL serum from red top tube

Rejection Criteria:

Hemolyzed specimens

Delivery Instructions:

Deliver to laboratory immediately after collection.

Analytic Time:

1 week

Reference Range:

                    Term               Pre-Term*
Newborns and   Range     Mean      Range      Mean
    Infants:  (ng/ml)   (ng/ml)   (ng/ml)    (ng/ml)
Birth:        15 - 109    59      21 -  93     51
2 Months:     15 - 109    55      23 - 163     81
4 Months:      7 - 124    50      23 - 171     74
6 Months:      7 -  93    41      15 - 132     61
12 Months:    15 - 101    56      15 - 179     77
*Values from preterm infants were determined at these ages
from expected term gestation.

Children and        Male                Female
Young adults:  Range     Mean      Range      Mean
              (ng/ml)   (ng/ml)   (ng/ml)    (ng/ml)
1 - 2 Years:  30 - 122    76      56 - 144     100
3 - 4 Years:  54 - 178   116      74 - 202     138
5 - 6 Years:  60 - 228   144      82 - 262     172
7 - 8 Years: 113 - 261   187     112 - 276     194
9 -10 Years: 123 - 275   199     140 - 308     224
11-12 Years: 139 - 395   267     132 - 376     254
13-14 Years: 152 - 540   346     192 - 640     416
15-16 Years: 257 - 601   429     217 - 589     403
17-18 Years: 236 - 524   380     176 - 452     314
19-20 Years: 281 - 510   371     217 - 475     323
Adults:
21-30 Years: 155 - 432   289      87 - 368     237

Contact the laboratory for age-related IGF-1 values in older adults.

Comments:

Patient's age and sex required on requisition.  Must be processed in 
laboratory within one hour of collection.

Methodology:

Blocking RadioImmunoassay (RIA) after acid:alcohol extraction

CPT Code:

84305

See also:
Insulin Like Growth Factor Binding Protein I (IGFBP-1), Serum
Insulin Like Growth Factor Binding Protein III (IGFBP-3), Serum
Insulin Like Growth Factor II (IGF-II), Serum

See Additional Information:
Specimens Requiring Immediate Delivery