Ophthalmology and Visual Sciences

UI glaucoma group wins award at APAO in India

Associate Professor of Ophthalmology & Visual Science, John Fingert, MD, PhD, presented the paper entitled,  "Transgenic TBK1 mice and normal tension glaucoma" at the 2013 Asia Pacific Academy of Ophthalmology(APAO) in Hyderabad, India on January 17, 2013.

The presentation described the production of a mouse colony that carries the same TBK1 gene mutation that causes glaucoma in humans.

Research data shows these mice with a TBK1 mutation develop the same type of low pressure glaucoma as humans that carry a TBK1 gene mutation. This transgenic TBK1 mouse will be a powerful tool for investigating the process by which a TBK1 mutation leads to optic nerve damage and glaucoma. Additionally, studies of the transgenic mice will allow development and testing of new glaucoma treatments specifically designed to target the defect in TBK1 that causes disease.

Dr. Fingert and his colleagues from the University of Iowa (Drs. Robert Mullins and Michael Anderson) received the Best Paper Award for this presentation.