Pathology

  • Michael Knudson, MD, PhD Received the Donald D. Dorfman Research Award

    Michael Knudson, MD, PhD receiving Donald D. Dorfman Research Award
    Left to right: George Weiner, MD, Jonathan Dorfman, Lorraine Dorfman and Michael Knudson, MD, PhD

    The Donald D. Dorfman Research Award recognizes one investigator in basic research and one investigator in clinical/population research in leukemia and lymphoma. The award was presented by Jonathan and Lorraine Dorfman at a recognition event held on Friday, October 25, 2013.

    Michael Knudson, MD, PhD, was selected for this year’s Donald D. Dorfman Award for Basic Research for his paper entitled “2-deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines.” published in Oncogene. This paper examined novel approaches to the treatment of lymphoma using 2-deoxyglucose, a drug that targets the abnormal metabolism that is prevalent in lymphoma cells.

    This award includes support for research on Lymphoma that will be utilized by Dr. Knudson and Dr. Janz to study the role of metformin in mouse models of lymphoma.