Vladimir Badovinac Laboratory—Department of Pathology

Deepa Rai, MS

Research Assistant
deepa-rai@uiowa.edu

Department of Pathology
1160 Medical Laboratories
500 Newton Road
University of Iowa
Iowa City, IA 52242-1109

Lab: 319-384-2929

Training

BS, Cell and Molecular Biology, Winona State University, 2006
MS, Pathology, University of Iowa, 2010

Research

My research focuses on how repeated antigenic stimulations influence the generation and longevity of memory CD8 T cell population and whether/how an individual host maintains the improved and protective immune responses to the re-infection.

Publications

1. Condotta SA, Rai D, James BR, Griffith TS, Badovinac VP. Sustained and Incomplete Recovery of Naive CD8+ T Cell Precursors after Sepsis Contributes to Impaired CD8+ T Cell Responses to Infection. J Immunol. 2013; 190(5): 1991-2000.
2. Nolz JC, Rai D, Badovinac VP, Harty JT. Division-linked generation of ‘death-intermediates’ regulates the numerical stability of memory CD8 T cells. Proc Natl Acad Sci. 2012 Apr 17;109(16):6199-204.
3. Gurung P, Rai D, Condotta SA, Babcock JC, Badovinac VP, Griffith TS. Immune Unresponsivenss to Secondary heterologous bacterial Infection after Sepsis Induction is Trail Dependent. J Immnol. 2011 Sep 1; 187(5):2148-54.
4. Wirth TC, Xue HH, Rai D, Sabel JL, Bair T, Harty JT, Badovinac VP. Repetitive Antigen Stimulations Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8 T Cell Differentiation. Immunity. 2010 Jul 23;33(1):128-40.
5. Rai D, Pham NL, Harty JT, Badovinac VP. Tracking the total CD8 T Cell Response to Infection Reveals stantial Discordance in Magnitude and Kinetics between Inbred and Outbred Hosts. J Immunol. 2009 Dec 15;183(12):7672-81.